| 1 |
31827016 | Structure and function of the insulin receptor-a personal perspective. | 2019 |
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| 2 |
25623440 | Network analysis of gene expression in peripheral blood identifies mTOR and NF-κB pathways involved in antipsychotic-induced extrapyramidal symptoms. | 2015 Oct |
2 |
| 3 |
25687571 | The last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) plays a central role in insulin signaling and the Golgi/endosomes protein network. | 2015 Apr |
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| 4 |
26276395 | Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells. | 2015 Oct 15 |
2 |
| 5 |
26438154 | BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose Homeostasis. | 2015 Dec |
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| 6 |
24867955 | Insulin receptor activation with transmembrane domain ligands. | 2014 Jul 11 |
2 |
| 7 |
23314177 | Ahsg-fetuin blocks the metabolic arm of insulin action through its interaction with the 95-kD β-subunit of the insulin receptor. | 2013 Apr |
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| 8 |
23935097 | A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor. | 2013 Sep 27 |
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| 9 |
22298784 | Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin receptor-dependent insulin signaling in early phase of differentiation. | 2012 Mar 30 |
2 |
| 10 |
22393939 | Small-molecule ATP-competitive dual IGF-1R and insulin receptor inhibitors: structural insights, chemical diversity and molecular evolution. | 2012 Mar |
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| 11 |
22992069 | Assessing the range of kinase autoinhibition mechanisms in the insulin receptor family. | 2012 Dec 1 |
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| 12 |
19206072 | Synthetic pentapeptides inhibiting autophosphorylation of insulin receptor in a non-ATP-competitive mechanism. | 2009 May |
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| 13 |
16567414 | Tannic acid, a potent inhibitor of epidermal growth factor receptor tyrosine kinase. | 2006 Mar |
1 |
| 14 |
11390649 | Intrasteric inhibition of ATP binding is not required to prevent unregulated autophosphorylation or signaling by the insulin receptor. | 2001 Jul |
2 |
| 15 |
10891367 | Development and comparison of two 3T3-L1 adipocyte models of insulin resistance: increased glucose flux vs glucosamine treatment. | 2000 Jul 14 |
2 |
| 16 |
10049496 | A basic residue, Lys 782, composes part of the ATP-binding site on the epidermal growth factor receptor tyrosine kinase. | 1999 Mar 1 |
1 |
| 17 |
9685425 | Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP. | 1998 Aug 7 |
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| 18 |
9054578 | Conformational changes of the insulin receptor upon insulin binding and activation as monitored by fluorescence spectroscopy. | 1997 Mar 4 |
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| 19 |
9312016 | Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog. | 1997 Sep 15 |
2 |
| 20 |
8666152 | The inhibition of the insulin receptor by the receptor protein PC-1 is not specific and results from the hydrolysis of ATP. | 1996 Jul |
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| 21 |
9082618 | [The homology of the primary structure of the third cytoplasmic domains in rhodopsin-type receptors and of the cytoplasmic tail in the beta-subunit of the insulin receptor]. | 1996 |
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| 22 |
7702578 | Mutagenic structure/function analysis of the cytoplasmic cysteines of the insulin receptor. | 1995 Mar 15 |
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| 23 |
8093061 | Annexin I as a potential inhibitor of insulin receptor protein tyrosine kinase. | 1994 Sep 15 |
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| 24 |
8243830 | Ala1048-->Asp mutation in the kinase domain of insulin receptor causes defective kinase activity and insulin resistance. | 1993 Dec |
2 |
| 25 |
8401310 | Demonstration of putative subunit(s) of a novel insulin receptor-associated 66 kDa GTP-binding protein, Gir. | 1993 Jul |
1 |
| 26 |
8504095 | Insulin receptor autophosphorylation. I. Autophosphorylation kinetics of the native receptor and its cytoplasmic kinase domain. | 1993 Jun 8 |
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| 27 |
1385393 | The reversible and irreversible autophosphorylations of insulin receptor kinase. | 1992 Nov 5 |
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| 28 |
2200525 | The ligand binding characteristics of a kinase-defective A/K1018 human insulin receptor expressed in Rat 1 fibroblasts. | 1990 Jul 12 |
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| 29 |
2849108 | ATP sensitizes the insulin receptor to insulin. | 1988 Dec |
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| 30 |
2957374 | The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulation. | 1987 Aug 25 |
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| 31 |
3038872 | Identification of insulin receptor tyrosine residues autophosphorylated in vitro. | 1987 Jul 25 |
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| 32 |
3101064 | Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity. | 1987 Feb |
3 |
| 33 |
3017297 | Protein kinase activity of the insulin receptor. | 1986 Apr 1 |
1 |
| 34 |
3518702 | Tyrosine kinase activity of insulin receptors from human placenta. Effects of autophosphorylation and cyclic AMP-dependent protein kinase. | 1986 Feb 1 |
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| 35 |
3891757 | Subunit structure of the purified human placental insulin receptor. Intramolecular subunit dissociation by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. | 1985 Jul 15 |
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| 36 |
6374370 | ATP and other nucleoside triphosphates inhibit the binding of insulin to its receptor. | 1984 Jun |
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| 37 |
6340724 | The beta subunit of the insulin receptor is an insulin-activated protein kinase. | 1983 Feb 15 |
1 |
| 38 |
6353801 | [Linking of the insulin-receptor complex with the membrane transport system through ATP generation by plasma membranes]. | 1983 |
1 |
| 39 |
6849137 | Insulin receptor: evidence that it is a protein kinase. | 1983 Jan 21 |
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