Metformin

insulin receptor ; Homo sapiens







29 Article(s)
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Title
Pub. Year
#Total Relationships
1 35000900 Monogenic diabetes due to an INSR mutation in a child with severe insulin resistance. 2022 Jan 1 1
2 35182540 Proliferative cells in racemose neurocysticercosis have an active MAPK signalling pathway and respond to metformin treatment. 2022 May 1
3 33609563 Metformin turns 62 in pharmacotherapy: Emergence of non-glycaemic effects and potential novel therapeutic applications. 2021 May 5 1
4 34484117 Effects of Metformin on Reproductive, Endocrine, and Metabolic Characteristics of Female Offspring in a Rat Model of Letrozole-Induced Polycystic Ovarian Syndrome With Insulin Resistance. 2021 1
5 27633039 Relationships Between Metformin, Paraoxonase-1 and the Chemokine (C-C Motif) Ligand 2. 2016 1
6 27695899 Sequential cleavage of insulin receptor by calpain 2 and γ-secretase impairs insulin signalling. 2016 Dec 1
7 25849721 Changes in insulin receptor signaling underlie neoadjuvant metformin administration in breast cancer: a prospective window of opportunity neoadjuvant study. 2015 Mar 3 1
8 26045896 Reversing the reduced level of endometrial GLUT4 expression in polycystic ovary syndrome: a mechanistic study of metformin action. 2015 1
9 26372847 Different Effects of Metformin on the Hypothalamic-Pituitary-Thyroid Axis in Bromocriptine- and Cabergoline-treated Patients with Hashimoto's Thyroiditis and Glucose Metabolism Abnormalities. 2015 Oct 1
10 24603137 Human granulosa cells: insulin and insulin-like growth factor-1 receptors and aromatase expression modulation by metformin. 2014 4
11 24627035 Are growth factor receptors modulated by metformin in human endometrial stromal cells after stimulation with androgen and insulin? 2014 Aug 6
12 23141431 Metformin enhances the action of insulin on porcine granulosa-lutein cells in vitro. 2012 Dec 2
13 21597332 The insulin receptor substrate (IRS) proteins: at the intersection of metabolism and cancer. 2011 Jun 1 1
14 18972094 Combined thiazolidinedione-metformin treatment synergistically improves insulin signalling to insulin receptor substrate-1-dependent phosphatidylinositol 3-kinase, atypical protein kinase C and protein kinase B/Akt in human diabetic muscle. 2009 Jan 2
15 19679549 Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. 2009 Aug 15 2
16 15135305 Metformin (Glucophage) inhibits tyrosine phosphatase activity to stimulate the insulin receptor tyrosine kinase. 2004 Jun 1 9
17 12629126 Metformin rapidly increases insulin receptor activation in human liver and signals preferentially through insulin-receptor substrate-2. 2003 Mar 5
18 11601679 Monotherapy with metformin: does it improve hypoxia in type 2 diabetic patients? 2001 Sep 1
19 10456437 Metformin modulates insulin receptor signaling in normal and cholesterol-treated human hepatoma cells (HepG2). 1999 Jul 21 2
20 9514089 Stimulation of the intracellular portion of the human insulin receptor by the antidiabetic drug metformin. 1998 Feb 15 2
21 9137903 Effect of metformin on insulin-stimulated tyrosine kinase activity of erythrocytes from obese women with normal glucose tolerance. 1997 Apr 1
22 1543016 Metformin ameliorates extreme insulin resistance in a patient with anti-insulin receptor antibodies: description of insulin receptor and postreceptor effects in vivo and in vitro. 1992 Feb 3
23 3075902 Treatment--metformin. 1988 May 1
24 3126223 Effects of metformin and glibenclamide on insulin receptors in fibroblasts and tumor cells in vitro. 1987 Dec 1
25 3552772 Metformin enhances insulin binding to "in vitro" down regulated human fat cells. 1987 Feb 1
26 6350337 Metformin normalizes insulin binding to monocytes from obese nondiabetic subjects and obese type II diabetic patients. 1983 Oct 1
27 6360756 Insulin receptor binding to monocytes, insulin secretion, and glucose tolerance following metformin treatment. Results of a double-blind cross-over study in type II diabetics. 1983 Dec 1
28 6403102 Effect of metformin on insulin receptor binding and glycaemic control in type II diabetes. 1983 Mar 12 1
29 6405894 Effect of metformin on insulin receptor binding and diabetic control. 1983 May 14 1