Pub. Date : 2012 Dec
PMID : 23141431
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Metformin with insulin significantly increased mRNA expressions of INSR, IGF-1R, and IRS-1, while metformin alone had no significant effect. | Metformin | insulin receptor | Homo sapiens |
2 | And metformin with insulin had the significant effect on the protein activity (activation and phosphorylation) of downstream targets of INSR signaling pathway. | Metformin | insulin receptor | Homo sapiens |