| 1 |
34624079 | SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma. | 2022 Jan 27 |
1 |
| 2 |
35211429 | SHMT2 Drives the Progression of Colorectal Cancer by Regulating UHRF1 Expression. | 2022 |
2 |
| 3 |
35398308 | Downregulation of SHMT2 promotes the prostate cancer proliferation and metastasis by inducing epithelial-mesenchymal transition. | 2022 Jun 15 |
2 |
| 4 |
35422087 | SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells. | 2022 Apr 14 |
2 |
| 5 |
33456583 | Cytoplasmic SHMT2 drives the progression and metastasis of colorectal cancer by inhibiting β-catenin degradation. | 2021 |
2 |
| 6 |
33863325 | Silencing SHMT2 inhibits the progression of tongue squamous cell carcinoma through cell cycle regulation. | 2021 Apr 16 |
2 |
| 7 |
34215932 | Serine hydroxymethyltransferase 2: a novel target for human cancer therapy. | 2021 Dec |
1 |
| 8 |
34476002 | Roles of Mitochondrial Serine Hydroxymethyltransferase 2 (SHMT2) in Human Carcinogenesis. | 2021 |
2 |
| 9 |
31707355 | Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-d]pyrimidine Inhibitor Targeting Mitochondrial and Cytosolic One-Carbon Metabolism. | 2020 Jan |
2 |
| 10 |
32055850 | Glycine by MR spectroscopy is an imaging biomarker of glioma aggressiveness. | 2020 Jul 7 |
2 |
| 11 |
32142918 | Drosha-independent miR-6778-5p strengthens gastric cancer stem cell stemness via regulation of cytosolic one-carbon folate metabolism. | 2020 May 28 |
1 |
| 12 |
32330411 | Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2. | 2020 Jul 8 |
2 |
| 13 |
32903271 | Cancer proteome and metabolite changes linked to SHMT2. | 2020 |
4 |
| 14 |
33569544 | The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. | 2020 |
1 |
| 15 |
30964837 | SHMT2 Promotes Liver Regeneration Through Glycine-activated Akt/mTOR Pathway. | 2019 Jul |
6 |
| 16 |
31289137 | Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. | 2019 Oct |
1 |
| 17 |
31442042 | Study of SHMT2 Inhibitors and Their Binding Mechanism by Computational Alanine Scanning. | 2019 Sep 23 |
2 |
| 18 |
31773687 | High expression of SHMT2 is correlated with tumor progression and predicts poor prognosis in gastrointestinal tumors. | 2019 Nov |
2 |
| 19 |
29791506 | SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy. | 2018 May |
2 |
| 20 |
30228815 | SHMT2 Overexpression Predicts Poor Prognosis in Intrahepatic Cholangiocarcinoma. | 2018 |
2 |
| 21 |
30367038 | Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis. | 2018 Oct 26 |
2 |
| 22 |
28259896 | The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review). | 2017 Apr |
1 |
| 23 |
26824641 | Glycine supplementation in vitro enhances porcine preimplantation embryo cell number and decreases apoptosis but does not lead to live births. | 2016 Mar |
6 |
| 24 |
26975021 | Metabolic phenotype of bladder cancer. | 2016 Apr |
4 |
| 25 |
27391339 | Downregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma. | 2016 Aug 16 |
4 |
| 26 |
27666119 | Prognostic and therapeutic value of mitochondrial serine hydroxyl-methyltransferase 2 as a breast cancer biomarker. | 2016 Nov |
2 |
| 27 |
25855294 | SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. | 2015 Apr 16 |
3 |
| 28 |
25999742 | Positive correlation between expression level of mitochondrial serine hydroxymethyltransferase and breast cancer grade. | 2015 |
2 |
| 29 |
26482881 | NRF2 regulates serine biosynthesis in non-small cell lung cancer. | 2015 Dec |
1 |
| 30 |
24700805 | Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease. | 2014 Apr 3 |
1 |
| 31 |
24755469 | Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes. | 2014 Jun 1 |
1 |
| 32 |
23474074 | Glycine consumption and mitochondrial serine hydroxymethyltransferase in cancer cells: the heme connection. | 2013 May |
5 |
| 33 |
20093739 | A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis. | 2009 Dec |
1 |
| 34 |
19179765 | Branch-point stoichiometry can generate weak links in metabolism: the case of glycine biosynthesis. | 2008 Dec |
1 |
| 35 |
10716626 | Serine hydroxymethyltransferase and threonine aldolase: are they identical? | 2000 Mar |
1 |
| 36 |
10571879 | Glycine and serine catabolism in non-photosynthetic higher plant cells: their role in C1 metabolism. | 1999 Oct |
1 |
| 37 |
236734 | Methylmalonic acidaemia and nonketotic hyperglycinaemia. Clinical and biochemical aspects. | 1975 Feb |
1 |