Title : The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review).

Pub. Date : 2017 Apr

PMID : 28259896






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In the folate cycle, glycine and serine fuel the mitochondrial enzymes SHMT2, MTHFD2 and ALDH1L2, which play critical roles in the cancer survival and proliferation presumably through purine production. Glycine serine hydroxymethyltransferase 2 Homo sapiens