Poly I-C

tumor necrosis factor ; Mus musculus







57 Article(s)
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1 34454033 Maoto, a traditional Japanese medicine, controls acute systemic inflammation induced by polyI:C administration through noradrenergic function. 2022 Jan 5 2
2 33383149 IL-33 ameliorates liver injury and inflammation in Poly I:C and Concanavalin-A induced acute hepatitis. 2021 Jan 1
3 33442686 Double stranded RNA drives innate immune responses, sickness behavior and cognitive impairment dependent on dsRNA length, IFNAR1 expression and age. 2021 Jan 9 1
4 33892139 Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age. 2021 Jul 1
5 34028652 Dose-dependent therapeutic effects of topical 1,25 OH-vitamin D3 on corneal wound healing. 2021 May 1
6 34453520 Differential Effects of Viral Nucleic Acid Sensor Signaling Pathways on Testicular Sertoli and Leydig Cells. 2021 Dec 1 2
7 34665110 Viperin is anti-viral in vitro but is dispensable for restricting dengue virus replication or induction of innate and inflammatory responses in vivo. 2021 Oct 1
8 34903784 Distinct trans-placental effects of maternal immune activation by TLR3 and TLR7 agonists: implications for schizophrenia risk. 2021 Dec 13 2
9 32322251 Efficient Selection of New Immunobiotic Strains With Antiviral Effects in Local and Distal Mucosal Sites by Using Porcine Intestinal Epitheliocytes. 2020 1
10 32328062 Lipoteichoic Acid Is Involved in the Ability of the Immunobiotic Strain Lactobacillus plantarum CRL1506 to Modulate the Intestinal Antiviral Innate Immunity Triggered by TLR3 Activation. 2020 1
11 32328942 Combined Administration of TLR4 (LPS) and TLR3 (Poly I:C) Ligands to CBA Mice Elevates the Content of Osteogenic MSC by 1.6 Times and Increases Content of Bone Marrow MSC to Intermediate Level between Values Attained by Their Individual Administration. 2020 Apr 1
12 32390869 Protein Kinase C δ (PKCδ) Attenuates Bleomycin Induced Pulmonary Fibrosis via Inhibiting NF-κB Signaling Pathway. 2020 1
13 31057355 Intermittent Fasting Exacerbates the Acute Immune and Behavioral Sickness Response to the Viral Mimic Poly(I:C) in Mice. 2019 1
14 31500303 Production of IFNβ by Conventional Dendritic Cells after Stimulation with Viral Compounds and IFNβ-Independent IFNAR1-Signaling Pathways are Associated with Aggravation of Polymicrobial Sepsis. 2019 Sep 7 1
15 30613299 Anti-tumor macrophages activated by ferumoxytol combined or surface-functionalized with the TLR3 agonist poly (I : C) promote melanoma regression. 2018 1
16 28246473 Effect of toll-like receptor 3 agonist poly I:C on intestinal mucosa and epithelial barrier function in mouse models of acute colitis. 2017 Feb 14 1
17 28747347 TRIM8 Negatively Regulates TLR3/4-Mediated Innate Immune Response by Blocking TRIF-TBK1 Interaction. 2017 Sep 1 1
18 28958936 Suppression of neuroinflammation by matrix metalloproteinase-8 inhibitor in aged normal and LRRK2 G2019S Parkinson's disease model mice challenged with lipopolysaccharide. 2017 Nov 18 1
19 26772774 MECHANICAL VENTILATION AUGMENTS POLY(I:C)INDUCED LUNG INJURY VIA A WISP1-INTEGRIN β3 DEPENDENT PATHWAY IN MICE. 2016 2
20 26869429 Application of Magnesium Pyrophosphate-Based Sponge-Like Microparticles to Enhance the Delivery Efficiency and Adjuvant Effects of Polyriboinosinic-Polyribocytidylic Acid in Immune Cells. 2016 Feb 1
21 27311810 Polyinosinic-polycytidylic acid inhibits the differentiation of mouse preadipocytes through pattern recognition receptor-mediated secretion of tumor necrosis factor-α. 2016 Oct 3
22 27614570 Aripiprazole inhibits polyI:C-induced microglial activation possibly via TRPM7. 2016 Dec 1
23 25840915 Pattern recognition receptor-initiated innate antiviral responses in mouse epididymal epithelial cells. 2015 May 15 1
24 25950701 TNF-α Producing Innate Lymphoid Cells (ILCs) Are Increased in Active Celiac Disease and Contribute to Promote Intestinal Atrophy in Mice. 2015 2
25 26040668 Polyinosinic-Polycytidylic Acid Perturbs Ovarian Functions Through Toll-Like Receptor 3-Mediated Tumor Necrosis Factor A Production in Female Mice. 2015 Jul 2
26 26658504 Innate Immune Signaling Induces IL-7 Production, Early Inflammatory Responses, and Sjögren's-Like Dacryoadenitis in C57BL/6 Mice. 2015 Dec 1
27 23954861 Programmed necrosis, not apoptosis, is a key mediator of cell loss and DAMP-mediated inflammation in dsRNA-induced retinal degeneration. 2014 Feb 2
28 24179040 Diminazene aceturate (Berenil) modulates LPS induced pro-inflammatory cytokine production by inhibiting phosphorylation of MAPKs and STAT proteins. 2014 Oct 1
29 24729619 Polyinosinic-polycytidylic acid has therapeutic effects against cerebral ischemia/reperfusion injury through the downregulation of TLR4 signaling via TLR3. 2014 May 15 1
30 25158758 Astrocyte galectin-9 potentiates microglial TNF secretion. 2014 Aug 27 1
31 23023014 Activation of toll-like receptor 3 attenuates alcoholic liver injury by stimulating Kupffer cells and stellate cells to produce interleukin-10 in mice. 2013 Feb 1
32 23028093 Identification and characterization of poly(I:C)-induced molecular responses attenuated by nicotine in mouse macrophages. 2013 Jan 3
33 23640484 KRP-203, sphingosine 1-phosphate receptor type 1 agonist, ameliorates atherosclerosis in LDL-R-/- mice. 2013 Jul 1
34 22308357 Toll-like receptor 3 signaling converts tumor-supporting myeloid cells to tumoricidal effectors. 2012 Feb 7 2
35 22361747 Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice. 2012 May 1 1
36 22581266 Toll-like receptor-induced inflammatory cytokines are suppressed by gain of function or overexpression of Gα(i2) protein. 2012 Oct 1
37 22765163 TNF-alpha is a key mediator in the development of Th2 cell response to inhaled allergens induced by a viral PAMP double-stranded RNA. 2012 Sep 3
38 22809727 Fibronectin inhibits cytokine production induced by CpG DNA in macrophages without direct binding to DNA. 2012 Oct 1
39 22983393 Toll-like receptor 3 agonist Poly I:C protects against simulated cerebral ischemia in vitro and in vivo. 2012 Oct 1
40 21111765 Immunity by formulation design: induction of high CD8+ T-cell responses by poly(I:C) incorporated into the CAF01 adjuvant via a double emulsion method. 2011 Mar 30 2
41 21206981 Optimization of activation requirements of immature mouse dendritic JAWSII cells for in vivo application. 2011 Mar 1
42 20218969 Apolipoprotein E inhibits toll-like receptor (TLR)-3- and TLR-4-mediated macrophage activation through distinct mechanisms. 2010 Apr 28 1
43 20448144 Activation of natural killer cells inhibits liver regeneration in toxin-induced liver injury model in mice via a tumor necrosis factor-alpha-dependent mechanism. 2010 Jul 3
44 19036857 Astrocytes recognize intracellular polyinosinic-polycytidylic acid via MDA-5. 2009 Apr 8
45 19111017 Effect of polyI:C cotreatment on halothane-induced liver injury in mice. 2009 Jan 2
46 18331798 Tumor necrosis factor alpha mediates the lethal hepatotoxic effects of poly(I:C) in D-galactosamine-sensitized mice. 2008 Apr 4
47 18809435 Essential roles of SHPS-1 in induction of contact hypersensitivity of skin. 2008 Nov 16 1
48 17072335 Diminished lifespan and acute stress-induced death in DNA-PKcs-deficient mice with limiting telomeres. 2007 May 3 1
49 17196665 Toll-like receptor 3 agonist induces impairment of uterine vascular remodeling and fetal losses in CBA x DBA/2 mice. 2007 Jun 1
50 17267173 Influence of poly I:C on sickness behaviors, plasma cytokines, corticosterone and central monoamine activity: moderation by social stressors. 2007 May 1