Methotrexate

replication factor C (activator 1) 1 ; Mus musculus







9 Article(s)
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1 23904512 Folate transport in mouse cumulus-oocyte complexes and preimplantation embryos. 2013 Sep 2
2 11997266 Reduced folate carrier transports thiamine monophosphate: an alternative route for thiamine delivery into mammalian cells. 2002 Jun 2
3 10955817 Sensitivity to 5,10-dideazatetrahydrofolate is fully conserved in a murine leukemia cell line highly resistant to methotrexate due to impaired transport mediated by the reduced folate carrier. 2000 Aug 1
4 10385685 Pattern of mutations that results in loss of reduced folate carrier function under antifolate selective pressure augmented by chemical mutagenesis. 1999 Jul 1
5 10535753 Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier. 1999 Nov 15 4
6 9446553 A single amino acid difference within the folate transporter encoded by the murine RFC-1 gene selectively alters its interaction with folate analogues. Implications for intrinsic antifolate resistance and directional orientation of the transporter within the plasma membrane of tumor cells. 1998 Jan 30 2
7 9525881 A reduced folate carrier mutation produces substrate-dependent alterations in carrier mobility in murine leukemia cells and methotrexate resistance with conservation of growth in 5-formyltetrahydrofolate. 1998 Apr 3 2
8 9634005 Concentrating capacity of the human reduced folate carrier (hRFC1) in human ZR-75 breast cancer cell lines. 1998 May 15 1
9 9261128 Impact of overexpression of the reduced folate carrier (RFC1), an anion exchanger, on concentrative transport in murine L1210 leukemia cells. 1997 Aug 22 3