4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline

epidermal growth factor receptor ; Homo sapiens







121 Article(s)
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51 17627611 Assessment of 11C-labeled-4-N-(3-bromoanilino)-6,7-dimethoxyquinazoline as a positron emission tomography agent to monitor epidermal growth factor receptor expression. 2007 Sep 1
52 17934341 Signaling pathway for 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages. 2007 Aug 31 4
53 24557623 Ultravlolet-B induced expression of hypoxia-inducible factor 1α, transferrin receptor through EGFR/PI3K/AKT/DEC1 pathway. 2007 Feb 1
54 16300728 Induction of COX-2 protein expression by vanadate in A549 human lung carcinoma cell line through EGF receptor and p38 MAPK-mediated pathway. 2006 Jan 13 1
55 16331686 Prostaglandin E2 receptor EP1 transactivates EGFR/MET receptor tyrosine kinases and enhances invasiveness in human hepatocellular carcinoma cells. 2006 Apr 1
56 16410015 Inhibition of protein tyrosine phosphatase activity mediates epidermal growth factor receptor signaling in human airway epithelial cells exposed to Zn2+. 2006 Jul 1 2
57 16443372 Transforming growth factor alpha attenuates the functional expression of AMPA receptors in cortical GABAergic neurons. 2006 Apr 1
58 16773209 Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cells. 2006 Jul 3
59 16848764 EGFR-mediated expression of aquaporin-3 is involved in human skin fibroblast migration. 2006 Dec 1 2
60 16964427 UVB radiation induces expression of HIF-1alpha and VEGF through the EGFR/PI3K/DEC1 pathway. 2006 Oct 3
61 16969513 Paclitaxel and ceramide synergistically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells. 2006 Oct 6
62 17154492 Multitarget-directed drug design strategy: a novel molecule designed to block epidermal growth factor receptor (EGFR) and to exert proapoptotic effects. 2006 Nov 16 1
63 17361080 Epidermal growth factor-, transforming growth factor-beta-, retinoic acid- and 1,25-dihydroxyvitamin D3-regulated expression of the novel protein PTPIP51 in keratinocytes. 2006 2
64 15766561 An EGF receptor inhibitor induces RAR-beta expression in breast and ovarian cancer cells. 2005 Apr 22 2
65 15827339 Inhibition of the epidermal growth factor receptor increases expression of genes that stimulate inflammation, apoptosis, and cell attachment. 2005 Apr 1
66 15867774 The selective epidermal growth factor receptor tyrosine kinase inhibitor PD153035 suppresses expression of prometastasis phenotypes in malignant pleural mesothelioma cells in vitro. 2005 May 3
67 15952178 Heparin-binding epidermal growth factor-like growth factor stimulates cell proliferation in cerebral cortical cultures through phosphatidylinositol 3'-kinase and mitogen-activated protein kinase. 2005 Aug 15 3
68 15985706 Gastric mucin secretion in response to beta-adrenergic G protein-coupled receptor activation is mediated by SRC kinase-dependent epidermal growth factor receptor transactivation. 2005 Jun 1
69 16049334 Epidermal growth factor receptor signaling is partially responsible for the increased matrix metalloproteinase-1 expression in ocular epithelial cells after UVB radiation. 2005 Aug 1
70 16077934 Transient activation of EGFR/AKT cell survival pathway and expression of survivin contribute to reduced sensitivity of human melanoma cells to betulinic acid. 2005 Sep 2
71 16211241 Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death. 2005 Nov 2
72 14996711 Inhibition of epidermal growth factor receptor signaling protects human malignant glioma cells from hypoxia-induced cell death. 2004 Mar 1 1
73 15009100 Antipsoriatic drug anthralin induces EGF receptor phosphorylation in keratinocytes: requirement for H(2)O(2) generation. 2004 Feb 2
74 15054105 Role of PPARgamma and EGFR signalling in the urothelial terminal differentiation programme. 2004 Apr 15 1
75 15070968 Insulin-like growth factor binding protein-3 expression is associated with growth stimulation of T47D human breast cancer cells: the role of altered epidermal growth factor signaling. 2004 Apr 2
76 15177934 Involvement of MAP-kinase, PI3-kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells. 2004 Aug 15 1
77 15191553 The neuronal nitric oxide synthase is upregulated in mouse skin repair and in response to epidermal growth factor in human HaCaT keratinocytes. 2004 Jul 1
78 15304097 Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38. 2004 Sep 2
79 15381832 Secretion of gastric mucus phospholipids in response to beta-adrenergic G protein-coupled receptor activation is mediated by SRC kinase-dependent epidermal growth factor receptor transactivation. 2004 Sep 1
80 15562758 [Role of PD153035 in the induction of apoptosis of XG-1 myeloma cell line]. 2004 Oct 3
81 20641571 [O-11C-methyl]4-N-(3-Bromoanilino)-6,7-dimethoxyquinazoline 2004 3
82 12594213 Mutation of threonine 766 in the epidermal growth factor receptor reveals a hotspot for resistance formation against selective tyrosine kinase inhibitors. 2003 Apr 25 4
83 12733059 TPA-induced signal transduction: a link between PKC and EGFR signaling modulates the assembly of intercellular junctions in Caco-2 cells. 2003 Jun 1
84 12794766 Synergistic antiproliferative and apoptotic effects induced by epidermal growth factor receptor and protein kinase a inhibitors in human prostatic cancer cell lines. 2003 Aug 10 2
85 12876202 Profiling receptor tyrosine kinase activation by using Ab microarrays. 2003 Aug 5 1
86 12915106 Mechanisms of Zn(2+)-induced signal initiation through the epidermal growth factor receptor. 2003 Aug 15 2
87 12943688 Expression of ErbB receptors in ES cell-derived cardiomyocytes. 2003 Sep 12 1
88 12966092 Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation. 2003 Nov 21 2
89 14500405 Epidermal growth factor receptor-stimulated activation of phospholipase Cgamma-1 promotes invasion of head and neck squamous cell carcinoma. 2003 Sep 1 1
90 14612544 Resistance to small molecule inhibitors of epidermal growth factor receptor in malignant gliomas. 2003 Nov 1 3
91 11792073 Activation of EGF receptors mediates pulmonary vasoconstriction induced by residual oil fly ash. 2002 Jan-Feb 1
92 11943650 Cyclic stretch activates ERK1/2 via G proteins and EGFR in alveolar epithelial cells. 2002 May 2
93 11943669 Role of Ras in metal-induced EGF receptor signaling and NF-kappaB activation in human airway epithelial cells. 2002 May 1
94 11992543 Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines. 2002 Jun 1 1
95 12171571 4-anilino-3-quinolinecarbonitriles: an emerging class of kinase inhibitors. 2002 Sep 2
96 11178955 BIBX1382BS, but not AG1478 or PD153035, inhibits the ErbB kinases at different concentrations in intact cells. 2001 Feb 16 2
97 11179516 Transmodulation of epidermal growth factor receptor mediates IL-1 beta-induced MMP-1 expression in cultured human keratinocytes. 2001 Mar 2
98 11257459 EGF receptor crosstalks with cytokine receptors leading to the activation of c-Jun kinase in response to UV irradiation in human keratinocytes. 2001 Feb 1
99 11431328 Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor receptor-dependent migration and induces aggregation of nh(2)-terminal FAK in the nuclei of apoptotic glioblastoma cells. 2001 Jul 1 1
100 11562388 Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells. 2001 Sep 19 1