gemcitabine

epidermal growth factor receptor ; Homo sapiens







81 Article(s)
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1 32924987 Identification of a novel CpG methylation signature to predict prognosis in lung squamous cell carcinoma. 2021 1
2 33288882 Selective inhibition of stemness through EGFR/FOXA2/SOX9 axis reduces pancreatic cancer metastasis. 2021 Jan 1
3 33432347 Epidermal growth factor receptor promotes tumor progression and contributes to gemcitabine resistance in osteosarcoma. 2021 Mar 2 5
4 33878513 CUDC-101 enhances the chemosensitivity of gemcitabine-treated lymphoma cells. 2021 Jul 1
5 34061460 Lung squamous cell carcinoma with severe hypomagnesemia due to cisplatin plus gemcitabine in combination with necitumumab therapy: A case report. 2021 Jul 2
6 34123574 Priming of pancreatic cancer cells with bispecific antibody armed activated T cells sensitizes tumors for enhanced chemoresponsiveness. 2021 Jun 1 1
7 34238922 Exosomal annexin A6 induces gemcitabine resistance by inhibiting ubiquitination and degradation of EGFR in triple-negative breast cancer. 2021 Jul 8 3
8 34805140 Effect of Photodynamic Therapy on Gemcitabine-Resistant Cholangiocarcinoma in vitro and in vivo Through KLF10 and EGFR. 2021 3
9 32111094 Local Delivery of Gemcitabine Inhibits Pancreatic and Cholangiocarcinoma Tumor Growth by Promoting Epidermal Growth Factor Receptor Degradation. 2020 Feb 26 2
10 32111744 Anti-EGFR Monoclonal Antibodies in Advanced Biliary Tract Cancer: A Systematic Review and Meta-analysis. 2020 Mar-Apr 1
11 32235891 Hexosamine pathway inhibition overcomes pancreatic cancer resistance to gemcitabine through unfolded protein response and EGFR-Akt pathway modulation. 2020 May 1
12 32622356 Gallbladder cancer with EGFR mutation and its response to GemOx with erlotinib: a case report and review of literature. 2020 Jul 4 1
13 30679315 A Phase II Randomized Trial of Panitumumab, Erlotinib, and Gemcitabine Versus Erlotinib and Gemcitabine in Patients with Untreated, Metastatic Pancreatic Adenocarcinoma: North Central Cancer Treatment Group Trial N064B (Alliance). 2019 May 3
14 31289485 Positive PD-L1 expression is predictive for patients with advanced EGFR wild-type non-small cell lung cancer treated with gemcitabine and cisplatin. 2019 Jul 1
15 31387179 Enhancement of chemosensitivity by WEE1 inhibition in EGFR-TKIs resistant non-small cell lung cancer. 2019 Sep 2
16 31550632 Electrochemical molecularly bioimprinted siloxane biosensor on the basis of core/shell silver nanoparticles/EGFR exon 21 L858R point mutant gene/siloxane film for ultra-sensing of Gemcitabine as a lung cancer chemotherapy medication. 2019 Dec 1 3
17 29141539 Selectively Targeted Anti-Neoplastic Cytotoxicity of Three Immunopharmaceuticals with Covalently Bound Fludarabine, Gemcitabine and Dexamethasone Moieties Synthesized Utilizing Organic Chemistry Reactions in a Multi-Stage Regimen. 2018 1
18 29352306 Prognostic and predictive role of EGFR pathway alterations in biliary cancer patients treated with chemotherapy and anti-EGFR. 2018 1
19 29851753 Downregulation of GEP100 Improved the Growth Inhibition Effect of Erlotinib Through Modulating Mesenchymal Epithelial Transition Process in Pancreatic Cancer. 2018 Jul 1
20 30407790 Epidermal Growth Factor Receptor-Targeting Peptide Nanoparticles Simultaneously Deliver Gemcitabine and Olaparib To Treat Pancreatic Cancer with Breast Cancer 2 ( BRCA2) Mutation. 2018 Nov 27 3
21 28719220 EGFR-Targeted Cationic Polymeric Mixed Micelles for Codelivery of Gemcitabine and miR-205 for Treating Advanced Pancreatic Cancer. 2017 Sep 5 1
22 28927112 Non-small cell lung cancer PC-9 cells exhibit increased sensitivity to gemcitabine and vinorelbine upon acquiring resistance to EGFR-tyrosine kinase inhibitors. 2017 Sep 4
23 28938567 Gemcitabine-induced heparanase promotes aggressiveness of pancreatic cancer cells via activating EGFR signaling. 2017 Aug 29 2
24 26626700 EGFR-Targeted Polymeric Mixed Micelles Carrying Gemcitabine for Treating Pancreatic Cancer. 2016 Jan 11 1
25 26650486 The relationship between RRM1 gene polymorphisms and effectiveness of gemcitabine-based first-line chemotherapy in advanced NSCLC patient. 2016 Sep 1
26 26656632 EGFR-targeted gelatin nanoparticles for systemic administration of gemcitabine in an orthotopic pancreatic cancer model. 2016 Apr 6
27 27070783 Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1, 2 and 3 in Periampullary Adenocarcinoma. 2016 1
28 27101576 miR-216b Targets FGFR1 and Confers Sensitivity to Radiotherapy in Pancreatic Ductal Adenocarcinoma Patients Without EGFR or KRAS Mutation. 2016 Oct 1
29 27556697 Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling. 2016 Sep 20 4
30 32263194 Development of gelatin nanoparticles conjugated with phytohemagglutinin erythroagglutinating loaded with gemcitabine for inducing apoptosis in non-small cell lung cancer cells. 2016 Apr 14 1
31 25550550 KML001 enhances anticancer activity of gemcitabine against pancreatic cancer cells. 2015 Jan 1
32 25776490 Molecularly targeted gemcitabine-loaded nanoparticulate system towards the treatment of EGFR overexpressing lung cancer. 2015 Mar 3
33 25821636 Simultaneous Dual Selective Targeted Delivery of Two Covalent Gemcitabine Immunochemotherapeutics and Complementary Anti-Neoplastic Potency of [Se]-Methylselenocysteine. 2015 Jan 6
34 26046796 Erlotinib is effective in pancreatic cancer with epidermal growth factor receptor mutations: a randomized, open-label, prospective trial. 2015 Jul 20 1
35 26056353 Phase I Clinical Trial to Determine the Feasibility and Maximum Tolerated Dose of Panitumumab to Standard Gemcitabine-Based Chemoradiation in Locally Advanced Pancreatic Cancer. 2015 Oct 15 2
36 24142531 Efficacy of nimotuzumab plus gemcitabine usage as first-line treatment in patients with advanced pancreatic cancer. 2014 Mar 1
37 24838526 Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma. 2014 Jun 15 1
38 25041791 Dual blockade of epidermal growth factor receptor and insulin-like growth factor receptor-1 signaling in metastatic pancreatic cancer: phase Ib and randomized phase II trial of gemcitabine, erlotinib, and cixutumumab versus gemcitabine plus erlotinib (SWOG S0727). 2014 Oct 1 2
39 25844392 Anti-Neoplastic Cytotoxicity of Gemcitabine-(C4-amide)-[anti-EGFR] in Dual-combination with Epirubicin-(C3-amide)-[anti-HER2/neu] against Chemotherapeutic-Resistant Mammary Adenocarcinoma (SKBr-3) and the Complementary Effect of Mebendazole. 2014 Apr 9 4
40 23255896 Sorafenib combined with gemcitabine in EGFR-TKI-resistant human lung cancer cells. 2013 Jan 2
41 23420122 Synergistic interaction between sorafenib and gemcitabine in EGFR-TKI-sensitive and EGFR-TKI-resistant human lung cancer cell lines. 2013 Feb 4
42 23456778 Quality of life (QoL) analyses from OPTIMAL (CTONG-0802), a phase III, randomised, open-label study of first-line erlotinib versus chemotherapy in patients with advanced EGFR mutation-positive non-small-cell lung cancer (NSCLC). 2013 Jun 1
43 23890141 Efficacy and safety profile of combining agents against epidermal growth factor receptor or vascular endothelium growth factor receptor with gemcitabine-based chemotherapy in patients with advanced pancreatic cancer: a meta-analysis. 2013 Jul-Aug 3
44 23910066 Response to first-line chemotherapy in patients with non-small-cell lung cancer according to epidermal growth factor receptor and K-RAS mutation status. 2013 Nov 3
45 24025152 Inhibiting signal transducer and activator of transcription-3 increases response to gemcitabine and delays progression of pancreatic cancer. 2013 Sep 11 1
46 22186617 Genomics and pharmacogenomics of pancreatic adenocarcinoma. 2012 Feb 1
47 22521649 EGFR mutations as a predictive marker of cytotoxic chemotherapy. 2012 Aug 2
48 23030589 Aptamer-mediated delivery of chemotherapy to pancreatic cancer cells. 2012 Oct 2
49 20705357 First-line therapy and methylation status of CHFR in serum influence outcome to chemotherapy versus EGFR tyrosine kinase inhibitors as second-line therapy in stage IV non-small-cell lung cancer patients. 2011 Apr 1
50 21080748 Erlotinib resistance is altered after gemcitabine chemotherapy for recurrent non-small-cell lung cancer. 2011 2