| 1 |
35303882 | Cholesterol promotes EGFR-TKIs resistance in NSCLC by inducing EGFR/Src/Erk/SP1 signaling-mediated ERRĪ± re-expression. | 2022 Mar 18 |
6 |
| 2 |
32140747 | Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity. | 2021 Jan |
2 |
| 3 |
33161461 | Bariatric Surgery Is Protective Against Renal Function Decline in Severely Obese Patients in the Long-Term. | 2021 Mar |
1 |
| 4 |
33420027 | EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma. | 2021 Jan 8 |
2 |
| 5 |
33569299 | Cholesterol synthesis disruption combined with a molecule-targeted drug is a promising metabolic therapy for EGFR mutant non-small cell lung cancer. | 2021 Jan |
1 |
| 6 |
33999716 | Non-Small-Cell Lung Cancer Regression by siRNA Delivered Through Exosomes That Display EGFR RNA Aptamer. | 2021 Oct |
1 |
| 7 |
34242725 | Regulation of EGFR activation and signaling by lipids on the plasma membrane. | 2021 Jul |
2 |
| 8 |
34504181 | Regulation of low-density lipoprotein receptor expression in triple negative breast cancer by EGFR-MAPK signaling. | 2021 Sep 9 |
3 |
| 9 |
34961887 | In silico studies of interactions of peptide-conjugated cholesterol metabolites and betulinic acid with EGFR, LDR, and N-terminal fragment of CCKA receptors. | 2021 Dec 28 |
1 |
| 10 |
31751859 | Liver X Receptor Agonism Sensitizes a Subset of Hepatocellular Carcinoma to Sorafenib by Dual-Inhibiting MET and EGFR. | 2020 Jan |
2 |
| 11 |
32123859 | Lung cancer cells survive epidermal growth factor receptor tyrosine kinase inhibitor exposure through upregulation of cholesterol synthesis. | 2020 Feb |
1 |
| 12 |
32929357 | Statins ameliorate cholesterol-induced inflammation and improve AQP2 expression by inhibiting NLRP3 activation in the kidney. | 2020 |
1 |
| 13 |
30590459 | Lapatinib-induced annexin A6 upregulation as an adaptive response of triple-negative breast cancer cells to EGFR tyrosine kinase inhibitors. | 2019 Aug 22 |
1 |
| 14 |
30987997 | Cholesterol Induces Epithelial-to-Mesenchymal Transition of Prostate Cancer Cells by Suppressing Degradation of EGFR through APMAP. | 2019 Jun 15 |
6 |
| 15 |
31400433 | EGFR-targeted immunoliposomes as a selective delivery system of simvastatin, with potential use in treatment of triple-negative breast cancers. | 2019 Oct 5 |
2 |
| 16 |
31642000 | Metabolic syndrome is a predictor of decreased renal function among community-dwelling middle-aged and elderly Japanese. | 2019 Dec |
1 |
| 17 |
29215723 | High cholesterol in lipid rafts reduces the sensitivity to EGFR-TKI therapy in non-small cell lung cancer. | 2018 Sep |
4 |
| 18 |
29556289 | Pro-metastatic signaling of the trans fatty acid elaidic acid is associated with lipid rafts. | 2018 Apr |
2 |
| 19 |
28006834 | Pretreatment direct bilirubin and total cholesterol are significant predictors of overall survival in advanced non-small-cell lung cancer patients with EGFR mutations. | 2017 Apr 1 |
1 |
| 20 |
26589000 | Association of chitotriosidase enzyme activity and genotype with the risk of nephropathy in type 2 diabetes. | 2016 Apr |
1 |
| 21 |
26918609 | c-Src/Cav1-dependent activation of the EGFR by Dsg2. | 2016 Jun 21 |
1 |
| 22 |
27515591 | High Density Lipoprotein Cholesterol and the Risk of All-Cause Mortality among U.S. Veterans. | 2016 Oct 7 |
5 |
| 23 |
24798787 | Enhancement of tumor uptake and therapeutic efficacy of EGFR-targeted antibody cetuximab and antibody-drug conjugates by cholesterol sequestration. | 2015 Jan 1 |
5 |
| 24 |
25901093 | Rate of change in renal function and mortality in elderly treated hypertensive patients. | 2015 Jul 7 |
1 |
| 25 |
26344763 | Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR. | 2015 Sep 22 |
3 |
| 26 |
26535009 | Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptake. | 2015 Nov 3 |
4 |
| 27 |
26536269 | Plasma Membrane Organization of Epidermal Growth Factor Receptor in Resting and Ligand-Bound States. | 2015 Nov 3 |
4 |
| 28 |
24120917 | Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis. | 2014 Jan |
1 |
| 29 |
25171892 | Simvastatin Enhances the Effects of Radiotherapy and Cetuximab on a Cell Line (FaDu) Derived from a Squamous Cell Carcinoma of Head and Neck. | 2014 Aug |
1 |
| 30 |
23470845 | Association between a MYH9 polymorphism (rs3752462) and renal function in the Spanish RENASTUR cohort. | 2013 May 10 |
2 |
| 31 |
23758574 | Antiretroviral therapy-induced changes in plasma lipids and the risk of kidney dysfunction in HIV-infected men. | 2013 Oct |
1 |
| 32 |
24215069 | Cholesterol depletion inhibits epidermal growth factor receptor transactivation by angiotensin II in vascular smooth muscle cells. Role of cholesterol-rich microdomains and focal adhesions in angiotensin II signaling. | 2013 Nov 8 |
1 |
| 33 |
22432118 | Insulin resistance, cystatin C, and mortality among older adults. | 2012 Jun |
1 |
| 34 |
22776036 | Prevalence, determinants and co-morbidities of chronic kidney disease among First Nations adults with diabetes: results from the CIRCLE study. | 2012 Jul 9 |
1 |
| 35 |
21245384 | Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate ras signaling via phospholipase D2. | 2011 Mar |
3 |
| 36 |
21660955 | Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib. | 2011 Sep |
3 |
| 37 |
21853092 | EGF receptor exposed to oxidative stress acquires abnormal phosphorylation and aberrant activated conformation that impairs canonical dimerization. | 2011 |
1 |
| 38 |
22586629 | Nuclear receptor LXR as a novel therapeutic antitumoral target in glioblastoma. | 2011 Oct |
1 |
| 39 |
19945766 | Lipid raft modulation inhibits NSCLC cell migration through delocalization of the focal adhesion complex. | 2010 Aug |
1 |
| 40 |
19951711 | Amlodipine, a Ca2+ channel blocker, suppresses phosphorylation of epidermal growth factor receptor in human epidermoid carcinoma A431 cells. | 2010 Jan 16 |
1 |
| 41 |
20138837 | Lipid raft cholesterol and genistein inhibit the cell viability of prostate cancer cells via the partial contribution of EGFR-Akt/p70S6k pathway and down-regulation of androgen receptor. | 2010 Mar 5 |
1 |
| 42 |
20143338 | Compartmentalization of EGFR in cellular membranes: role of membrane rafts. | 2010 Apr 15 |
1 |
| 43 |
20211660 | Colocalization of mineralocorticoid and EGF receptor at the plasma membrane. | 2010 May |
2 |
| 44 |
20301084 | Do statins delay the incidence of ESRD in diabetic patients with moderate CKD? | 2010 May-Jun |
1 |
| 45 |
20516214 | Epidermal growth factor receptor activation remodels the plasma membrane lipid environment to induce nanocluster formation. | 2010 Aug |
1 |
| 46 |
19041887 | Epidemiology of chronic kidney disease: results from a population of older adults in Germany. | 2009 Feb |
1 |
| 47 |
18166162 | Dissecting lipid raft facilitated cell signaling pathways in cancer. | 2008 Apr |
1 |
| 48 |
18358509 | Prostate cancer: a model of integration of genomic and non-genomic effects of the androgen receptor in cell lines model. | 2008 Oct |
1 |
| 49 |
18727093 | Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation. | 2008 Dec |
1 |
| 50 |
19763245 | Multi-Target Approaches in Colon Cancer Chemoprevention Based on Systems Biology of Tumor Cell-Signaling. | 2008 May 2 |
1 |