Title : Liver X Receptor Agonism Sensitizes a Subset of Hepatocellular Carcinoma to Sorafenib by Dual-Inhibiting MET and EGFR.

Pub. Date : 2020 Jan

PMID : 31751859






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mechanically, the activation of LXR suppressed sorafenib dependent recruitment of MET and epidermal growth factor receptor (EGFR) in lipid rafts through cholesterol efflux. Cholesterol epidermal growth factor receptor Homo sapiens
2 Mechanically, the activation of LXR suppressed sorafenib dependent recruitment of MET and epidermal growth factor receptor (EGFR) in lipid rafts through cholesterol efflux. Cholesterol epidermal growth factor receptor Homo sapiens