Fluorouracil

epidermal growth factor receptor ; Homo sapiens







83 Article(s)
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1 34951582 5-Fluorouracil-Impregnated PLGA Coated Gold Nanoparticles for Augmented Delivery to Lung Cancer: In Vitro Investigations. 2022 1
2 35241559 Retrospective Study of Cisplatin/Carboplatin, 5-Fluorouracil Plus Cetuximab (EXTREME) for Advanced-stage Salivary Gland Cancer. 2022 Mar-Apr 2
3 35326562 Impact of Delaying the Addition of Anti-EGFR in First Line of RAS Wild-Type Metastatic Colorectal Cancer: A Propensity-Weighted Pooled Data Analysis. 2022 Mar 10 1
4 33349222 Anti-EGFR-mAb and 5-Fluorouracil Conjugated Polymeric Nanoparticles for Colorectal Cancer. 2021 2
5 33538278 Cetuximab functionalization strategy for combining active targeting and antimigration capacities of a hybrid composite nanoplatform applied to deliver 5-fluorouracil: toward colorectal cancer treatment. 2021 Mar 21 1
6 33951601 DNA damage response- and JAK-dependent regulation of PD-L1 expression in head and neck squamous cell carcinoma (HNSCC) cells exposed to 5-fluorouracil (5-FU). 2021 Aug 2
7 34026617 Molecular Mechanisms of Chemotherapy Resistance in Head and Neck Cancers. 2021 1
8 34097885 Tumor-Specific Delivery of 5-Fluorouracil-Incorporated Epidermal Growth Factor Receptor-Targeted Aptamers as an Efficient Treatment in Pancreatic Ductal Adenocarcinoma Models. 2021 Sep 4
9 34589581 Targeting EGFR sensitizes 5-Fu-resistant colon cancer cells through modification of the lncRNA-FGD5-AS1-miR-330-3p-Hexokinase 2 axis. 2021 Dec 17 7
10 31837576 Management of recurrent and metastatic oral cavity cancer: Raising the bar a step higher. 2020 Feb 1
11 31840981 Enzymes Photo-Cross-Linked to Live Cell Receptors Retain Activity and EGFR Inhibition after Both Internalization and Recycling. 2020 Jan 15 1
12 31896739 Over-expression of EGFR regulated by RARA contributes to 5-FU resistance in colon cancer. 2020 Jan 2 4
13 31947551 Anti-EGFR-Coated Gold Nanoparticles In Vitro Carry 5-Fluorouracil to Colorectal Cancer Cells. 2020 Jan 14 4
14 31959339 Cisplatin and 5-fluorouracil with or without epidermal growth factor receptor inhibition panitumumab for patients with non-resectable, advanced or metastatic oesophageal squamous cell cancer: a prospective, open-label, randomised phase III AIO/EORTC trial (POWER). 2020 Feb 1
15 32043796 Withholding the Introduction of Anti-Epidermal Growth Factor Receptor: Impact on Outcomes in RAS Wild-Type Metastatic Colorectal Tumors: A Multicenter AGEO Study (the WAIT or ACT Study). 2020 Feb 1
16 32742490 Combinational inhibition of EGFR and YAP reverses 5-Fu resistance in colorectal cancer. 2020 1
17 33033330 Targeted delivery of 5-fluorouracil-1-acetic acid (5-FA) to cancer cells overexpressing epithelial growth factor receptor (EGFR) using virus-like nanoparticles. 2020 Oct 8 1
18 33408498 The Prognostic Significance of 5-Fluorouracil Induced Inflammation and Immuno-Modulation in Colorectal Cancer Patients. 2020 2
19 30662270 Complete response with fluorouracil and irinotecan with a BRAFV600E and EGFR inhibitor in BRAF-mutated metastatic colorectal cancer: a case report. 2019 2
20 30825616 Induction of autophagy enhances apoptotic cell death via epidermal growth factor receptor inhibition by canertinib in cervical cancer cells. 2019 May 4
21 31189612 Vorinostat Potentiates 5-Fluorouracil/Cisplatin Combination by Inhibiting Chemotherapy-Induced EGFR Nuclear Translocation and Increasing Cisplatin Uptake. 2019 Aug 2
22 31346466 A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab. 2019 2
23 31488078 Combined targeting of HER-2 and HER-3 represents a promising therapeutic strategy in colorectal cancer. 2019 Sep 5 1
24 31696188 Bypassing pro-survival and resistance mechanisms of autophagy in EGFR-positive lung cancer cells by targeted delivery of 5FU using theranostic Ag2S quantum dots. 2019 Dec 14 3
25 29086459 Epidermal Growth Factor and Granulocyte Colony Stimulating Factor Signaling Are Synergistic for Hematopoietic Regeneration. 2018 Feb 2
26 29480364 Combination of S-1 and gefitinib increases the sensitivity to radiotherapy in lung cancer cells. 2018 Apr 1
27 29864476 Skin cancer treatment effectiveness is improved by iontophoresis of EGFR-targeted liposomes containing 5-FU compared with subcutaneous injection. 2018 Aug 10 3
28 30056083 Manuka honey synergistically enhances the chemopreventive effect of 5-fluorouracil on human colon cancer cells by inducing oxidative stress and apoptosis, altering metabolic phenotypes and suppressing metastasis ability. 2018 Oct 1
29 27878272 miR-20b reduces 5-FU resistance by suppressing the ADAM9/EGFR signaling pathway in colon cancer. 2017 Jan 2
30 26505786 Combinatorial Effects of Curcumin with an Anti-Neoplastic Agent on Head and Neck Squamous Cell Carcinoma Through the Regulation of EGFR-ERK1/2 and Apoptotic Signaling Pathways. 2016 Jan 11 1
31 27091477 Epidermal growth factor receptor inhibitor with fluorouracil, leucovorin, and irinotecan as an alternative treatment for advanced upper tract urothelial carcinoma: a case report. 2016 Apr 18 1
32 27268079 Epidermal growth factor signals regulate dihydropyrimidine dehydrogenase expression in EGFR-mutated non-small-cell lung cancer. 2016 Jun 6 4
33 27340349 Treatment dilemmas of cetuximab combined with chemotherapy for metastatic colorectal cancer. 2016 Jun 21 2
34 27602148 Enhancing chemosensitivity in oral squamous cell carcinoma by lentivirus vector-mediated RNA interference targeting EGFR and MRP2. 2016 Sep 2
35 27610130 Prognostic Impact of mRNA Expression Levels of HER1-4 (ERBB1-4) in Patients with Locally Advanced Rectal Cancer. 2016 1
36 27833077 Anti-EGFR antibody sensitizes colorectal cancer stem-like cells to Fluorouracil-induced apoptosis by affecting autophagy. 2016 Dec 6 2
37 25573239 Favorable effect of the combination of vinorelbine and dihydropyrimidine dehydrogenase‑inhibitory fluoropyrimidine in EGFR‑mutated lung adenocarcinoma: retrospective and in vitro studies. 2015 Mar 2
38 25750344 Associations between driver gene mutations and cytotoxic chemosensitivity in patients with non-small cell lung cancer. 2015 Mar 3
39 26088456 First-line anti-EGFR monoclonal antibodies in panRAS wild-type metastatic colorectal cancer: A systematic review and meta-analysis. 2015 Oct 1
40 26275292 Does the Chemotherapy Backbone Impact on the Efficacy of Targeted Agents in Metastatic Colorectal Cancer? A Systematic Review and Meta-Analysis of the Literature. 2015 1
41 24405586 High expression of dihydropyrimidine dehydrogenase in lung adenocarcinoma is associated with mutations in epidermal growth factor receptor: implications for the treatment of non--small-cell lung cancer using 5-fluorouracil. 2014 Mar 5
42 24591842 Cyclooxygenase-2 inhibitor is a robust enhancer of anticancer agents against hepatocellular carcinoma multicellular spheroids. 2014 1
43 22052826 Advances in the management of recurrent or metastatic squamous cell carcinoma of the head and neck. 2013 Mar 1
44 23708506 Lapatinib inhibits the growth of esophageal squamous cell carcinoma and synergistically interacts with 5-fluorouracil in patient-derived xenograft models. 2013 Aug 1
45 23755922 Epidermal growth factor receptor expression as prognostic marker in patients with anal carcinoma treated with concurrent chemoradiation therapy. 2013 Aug 1 2
46 23800895 Associations between genetic polymorphisms of epidermal growth factor receptor (EGFR) and survival of colorectal cancer (CRC) patients treated with 5-fluorouracil-based chemotherapy. 2013 Dec 5
47 23822592 Which is false: oxaliplatin or fluoropyrimidine? An analysis of patients with KRAS wild-type metastatic colorectal cancer treated with first-line epidermal growth factor receptor monoclonal antibody. 2013 Oct 4
48 24221219 [Therapy of recurrent and metastatic squamous cell carcinoma of the head and neck : highlights of the ASCO Meeting 2013]. 2013 Nov 1
49 24351824 Cbl-b enhances sensitivity to 5-fluorouracil via EGFR- and mitochondria-mediated pathways in gastric cancer cells. 2013 Dec 16 2
50 21947696 Prognosis of esophageal squamous cell carcinoma in patients positive for human epidermal growth factor receptor family can be improved by initial chemotherapy with docetaxel, fluorouracil, and cisplatin. 2012 Mar 1