Tyrosine

epidermal growth factor receptor ; Homo sapiens







1076 Article(s)
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1001 7679104 Amphiregulin induces tyrosine phosphorylation of the epidermal growth factor receptor and p185erbB2. Evidence that amphiregulin acts exclusively through the epidermal growth factor receptor at the surface of human epithelial cells. 1993 Feb 5 1
1002 7679612 Exogenous phosphotyrosine modulates epidermal growth factor receptor tyrosine phosphorylation. 1993 Feb 6
1003 7682060 Role of intracellular Ca2+ in the epidermal growth factor induced inhibition of protein tyrosine phosphatase activity in a breast cancer cell line. 1993 Mar 31 1
1004 7686167 Pretreatment with vitamin A inhibits transforming growth factor alpha stimulation of human mammary carcinoma cells. 1993 Jul 1
1005 7689859 Thrombin activation of human platelets causes tyrosine phosphorylation of PLC-gamma 2. 1993 Sep 13 1
1006 7690546 Differential induction of phosphatidylcholine hydrolysis, diacylglycerol formation and protein kinase C activation by epidermal growth factor and transforming growth factor-alpha in normal human skin fibroblasts and keratinocytes. 1993 Sep 1 1
1007 7694547 Dephosphorylation on tyrosine of epidermal growth factor receptor is inhibited by Ca2+ pretreatment in isolated liver membrane. 1993 Nov 15 1
1008 8018955 Finite proliferative lifespan in vitro of a human breast cancer cell strain isolated from a metastatic lymph node. 1993 Dec 3
1009 8101647 Shc products are substrates of erbB-2 kinase. 1993 Aug 1
1010 8162346 UVB radiation induces phosphorylation of the epidermal growth factor receptor, decreases EGF binding and blocks EGF induction of ornithine decarboxylase gene expression in SV40-transformed human keratinocytes. 1993 Dec 1
1011 8225779 Inhibition of binding of phospholipase C gamma 1 SH2 domains to phosphorylated epidermal growth factor receptor by phosphorylated peptides. 1993 Sep 5
1012 8253771 Expression of human tyrosine kinase-negative epidermal growth factor receptor amplifies signaling through endogenous murine epidermal growth factor receptor. 1993 Dec 15 2
1013 8317888 Interferon-enhancement of tyrosine phosphorylation of epidermal growth factor receptors in human breast carcinoma cells. 1993 May-Jun 2
1014 8382707 Anti-epidermal growth factor receptor monoclonal antibodies affecting signal transduction. 1993 Feb 4
1015 8396132 Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. 1993 Sep 15 1
1016 1321046 Large-scale purification and characterisation of a recombinant epidermal growth-factor receptor protein-tyrosine kinase. Modulation of activity by multiple factors. 1992 Jul 1 1
1017 1321807 Tyrosine phosphorylation of mitogen-activated protein kinase in cells with tyrosine kinase-negative epidermal growth factor receptors. 1992 Jul 25 3
1018 1323290 A highly conserved tyrosine residue at codon 845 within the kinase domain is not required for the transforming activity of human epidermal growth factor receptor. 1992 Jul 31 3
1019 1331123 Atypical receptor-mediated signal transduction events in the EGF-dependent growth-inhibited cell line, MDA-468. 1992 Nov 1
1020 1347529 Identification and biochemical characterization of novel putative substrates for the epidermal growth factor receptor kinase. 1992 Mar 15 2
1021 1349015 Heterodimerization of c-erbB2 with different epidermal growth factor receptor mutants elicits stimulatory or inhibitory responses. 1992 Apr 25 2
1022 1352397 erbB-2 autophosphorylation is required for mitogenic action and high-affinity substrate coupling. 1992 Jul 2
1023 1356764 A single amino acid substitution is sufficient to modify the mitogenic properties of the epidermal growth factor receptor to resemble that of gp185erbB-2. 1992 Nov 1
1024 1370492 Association of the tyrosine phosphorylated epidermal growth factor receptor with a 55-kD tyrosine phosphorylated protein at the cell surface and in endosomes. 1992 Jan 5
1025 1378752 Tumor necrosis factor regulates tyrosine phosphorylation on epidermal growth factor receptors in A431 carcinoma cells: evidence for a distinct mechanism. 1992 May 1
1026 1504015 Transforming growth factor beta modulates phosphorylation of the epidermal growth factor receptor and proliferation of A431 cells. 1992 Feb 1
1027 1512257 Activated Src tyrosine kinase phosphorylates Tyr-457 of bovine GTPase-activating protein (GAP) in vitro and the corresponding residue of rat GAP in vivo. 1992 Aug 25 2
1028 1537871 Expression of the human epidermal growth factor receptor in a murine T-cell hybridoma. A transmembrane protein tyrosine kinase can synergize with the T-cell antigen receptor. 1992 Mar 5 1
1029 1729595 A site of tyrosine phosphorylation in the C terminus of the epidermal growth factor receptor is required to activate phospholipase C. 1992 Jan 1
1030 1730638 Epidermal growth factor (EGF)-stimulated tyrosine phosphorylation and EGF receptor degradation in cells expressing EGF receptors truncated at residue 973. 1992 Jan 15 6
1031 1646987 The biological activity of the human epidermal growth factor receptor is positively regulated by its C-terminal tyrosines. 1991 May 5
1032 1647028 Phosphorylation of protein 4.1 on tyrosine-418 modulates its function in vitro. 1991 Jun 15 3
1033 1663789 Temperature-dependent tyrosine phosphorylation of microtubule-associated protein kinase in epidermal growth factor-stimulated human fibroblasts. 1991 Aug 2
1034 1683701 Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas. 1991 Dec 1 1
1035 1722417 Immunodetection of the ligand-activated receptor for epidermal growth factor. 1991 1
1036 1850098 The epidermal growth factor receptor phosphorylates GTPase-activating protein (GAP) at Tyr-460, adjacent to the GAP SH2 domains. 1991 May 3
1037 1903921 Distinct structural specificities for functional coupling of the epidermal growth factor receptor to calcium-signalling versus phospholipase A2 responses. 1991 May 1 1
1038 1988447 Antibody-induced dimerization activates the epidermal growth factor receptor tyrosine kinase. 1991 Jan 25 2
1039 1993654 Reconstitution of the high affinity epidermal growth factor receptor on cell-free membranes after transmodulation by platelet-derived growth factor. 1991 Feb 15 1
1040 2022652 Internalization and down-regulation of the human epidermal growth factor receptor are regulated by the carboxyl-terminal tyrosines. 1991 May 5 5
1041 2058454 Leflunomide (HWA 486), a novel immunomodulating compound for the treatment of autoimmune disorders and reactions leading to transplantation rejection. 1991 Jan 1
1042 2072905 The proliferative and morphologic responses of a colon carcinoma cell line (LIM 1215) require the production of two autocrine factors. 1991 Aug 1
1043 1688559 Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates. 1990 Jan 25 2
1044 1696547 Epidermal growth factor induces tyrosine phosphorylation of epidermal growth factor receptors not occupied with ligand in intact A431 cells. 1990 Jul 30 1
1045 1706616 Identification of autophosphorylation sites of HER2/neu. 1990 Jan 1
1046 1974718 The epidermal growth factor receptor and the product of the neu protooncogene are members of a receptor tyrosine phosphorylation cascade. 1990 Aug 1
1047 2105948 Multisite phosphorylation of the epidermal growth factor receptor. Use of site-directed mutagenesis to examine the role of serine/threonine phosphorylation. 1990 Feb 25 2
1048 2142159 Regulation of epidermal growth factor receptor signal transduction. Role of gangliosides. 1990 Jul 15 1
1049 2153302 Selectivity of phospholipase C phosphorylation by the epidermal growth factor receptor, the insulin receptor, and their cytoplasmic domains. 1990 Jan 1
1050 2155244 Preliminary characterization of phosphotyrosine phosphatase activities in human peripheral blood lymphocytes: identification of CD45 as a phosphotyrosine phosphatase. 1990 Feb 1