| 1 |
34626114 | Metformin Protects Against Inflammation, Oxidative Stress to Delay Poly I:C-Induced Aging-Like Phenomena in the Gut of an Annual Fish. | 2022 Feb 3 |
2 |
| 2 |
35181615 | Morphoproteomics Identifies SIRT1, EZH2 and CXCR4 Pathways in Diffuse Large B-Cell Lymphoma: Therapeutic Implications. | 2022 Jan |
1 |
| 3 |
34163481 | Metformin, Macrophage Dysfunction and Atherosclerosis. | 2021 |
1 |
| 4 |
34332919 | Pharmacological activation of SIRT1 by metformin prevented trauma-induced heterotopic ossification through inhibiting macrophage mediated inflammation. | 2021 Oct 15 |
5 |
| 5 |
34577590 | Metformin a Potential Pharmacological Strategy in Late Onset Alzheimer's Disease Treatment. | 2021 Sep 1 |
1 |
| 6 |
34630972 | Autophagy stimulation delayed biological aging and decreased cardiac differentiation in rabbit mesenchymal stem cells. | 2021 |
1 |
| 7 |
30572719 | Differential expressions of SIRT1, SIRT3, and SIRT4 in peripheral blood mononuclear cells from patients with type 2 diabetic retinopathy. | 2020 Oct |
1 |
| 8 |
32194991 | Metformin inhibits IL-1β secretion via impairment of NLRP3 inflammasome in keratinocytes: implications for preventing the development of psoriasis. | 2020 |
2 |
| 9 |
32404204 | Autophagy-dependent and -independent modulation of oxidative and organellar stress in the diabetic heart by glucose-lowering drugs. | 2020 May 13 |
1 |
| 10 |
32695253 | Metformin Protects ARPE-19 Cells from Glyoxal-Induced Oxidative Stress. | 2020 |
1 |
| 11 |
30710424 | Metformin and tenovin-6 synergistically induces apoptosis through LKB1-independent SIRT1 down-regulation in non-small cell lung cancer cells. | 2019 Apr |
5 |
| 12 |
31125865 | State of the art - sirtuin 1 in kidney pathology - clinical relevance. | 2019 Sep |
1 |
| 13 |
31273790 | AMPK-SIRT1-independent inhibition of ANGPTL3 gene expression is a potential lipid-lowering mechanism of metformin. | 2019 Sep |
4 |
| 14 |
31920356 | Differential Expression of Human N-Alpha-Acetyltransferase 40 (hNAA40), Nicotinamide Phosphoribosyltransferase (NAMPT) and Sirtuin-1 (SIRT-1) Pathway in Obesity and T2DM: Modulation by Metformin and Macronutrient Intake. | 2019 |
2 |
| 15 |
29110598 | SIRT1 as a Therapeutic Target in Diabetic Complications. | 2018 |
1 |
| 16 |
29457866 | Epigenetic effects of metformin: From molecular mechanisms to clinical implications. | 2018 Jul |
1 |
| 17 |
29739273 | Angiogenic Dysregulation in Pregnancy-Related Hypertension-A Role for Metformin. | 2018 Nov |
1 |
| 18 |
30459716 | Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation. | 2018 |
11 |
| 19 |
30559718 | Distinctive Roles of Sirtuins on Diabetes, Protective or Detrimental? | 2018 |
1 |
| 20 |
28249909 | Morphoproteomics Identifies SIRT1 and EZH2 Pathways as Commonalities in B-cell Acute Lymphoblastic Leukemia: Pathogenetic Implications and Opportunities for Therapeutic Intervention. | 2017 Jan |
1 |
| 21 |
28298952 | Insights for Oxidative Stress and mTOR Signaling in Myocardial Ischemia/Reperfusion Injury under Diabetes. | 2017 |
1 |
| 22 |
28445726 | Sirtuin-1 Activation Controls Tumor Growth by Impeding Th17 Differentiation via STAT3 Deacetylation. | 2017 Apr 25 |
1 |
| 23 |
28964787 | Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts. | 2017 Dec 28 |
4 |
| 24 |
29230104 | Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway. | 2017 |
3 |
| 25 |
26885898 | Metformin regulates oxLDL-facilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX-1-modulated oxidative signaling. | 2016 Mar 8 |
3 |
| 26 |
25131770 | SIRT1 regulates oncogenesis via a mutant p53-dependent pathway in hepatocellular carcinoma. | 2015 Jan |
3 |
| 27 |
25921843 | Metformin improves putative longevity effectors in peripheral mononuclear cells from subjects with prediabetes. A randomized controlled trial. | 2015 Jul |
2 |
| 28 |
26141671 | Metformin ameliorates the proinflammatory state in patients with carotid artery atherosclerosis through sirtuin 1 induction. | 2015 Nov |
5 |
| 29 |
26629991 | Metformin and Resveratrol Inhibited High Glucose-Induced Metabolic Memory of Endothelial Senescence through SIRT1/p300/p53/p21 Pathway. | 2015 |
1 |
| 30 |
24428821 | Metformin induces PGC-1α expression and selectively affects hepatic PGC-1α functions. | 2014 May |
2 |
| 31 |
24970682 | Metformin induces microRNA-34a to downregulate the Sirt1/Pgc-1α/Nrf2 pathway, leading to increased susceptibility of wild-type p53 cancer cells to oxidative stress and therapeutic agents. | 2014 Sep |
7 |
| 32 |
23315983 | Visfatin is expressed in human granulosa cells: regulation by metformin through AMPK/SIRT1 pathways and its role in steroidogenesis. | 2013 May |
1 |
| 33 |
23982736 | Low concentration of metformin induces a p53-dependent senescence in hepatoma cells via activation of the AMPK pathway. | 2013 Nov |
2 |
| 34 |
22378745 | A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells. | 2012 Jul 1 |
3 |
| 35 |
22442140 | Metformin, metabolic stress, and mitochondria. Focus on "A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells". | 2012 Jul 1 |
1 |
| 36 |
20812964 | Negative regulation of stress-induced matrix metalloproteinase-9 by Sirt1 in skin tissue. | 2010 Dec |
1 |