Title : Positive interaction between lapatinib and capecitabine in human breast cancer models: study of molecular determinants.

Pub. Date : 2012 Aug

PMID : 21623901






3 Functional Relationships(s)
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1 Lapatinib proved to markedly downregulate TS activity, thus suggesting a subsequent better efficacy of capecitabine. Lapatinib thymidylate synthetase Homo sapiens
2 Besides, modulation of TS expression by lapatinib makes its association with capecitabine a promising way to overcome breast cancers resistant in relation with TS overexpression. Lapatinib thymidylate synthetase Homo sapiens
3 Besides, modulation of TS expression by lapatinib makes its association with capecitabine a promising way to overcome breast cancers resistant in relation with TS overexpression. Lapatinib thymidylate synthetase Homo sapiens