| 51 |
25527123 | SC-III3, a novel scopoletin derivative, induces cytotoxicity in hepatocellular cancer cells through oxidative DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation. | 2014 Dec 19 |
2 |
| 52 |
23117293 | Curcumin enhances the response of non-Hodgkin's lymphoma cells to ionizing radiation through further induction of cell cycle arrest at the G2/M phase and inhibition of mTOR phosphorylation. | 2013 Jan |
2 |
| 53 |
23178571 | ATM-deficient human fibroblast cells are resistant to low levels of DNA double-strand break induced apoptosis and subsequently undergo drug-induced premature senescence. | 2013 Jan 4 |
1 |
| 54 |
23460736 | The ataxia telangiectasia mutated kinase pathway regulates IL-23 expression by human dendritic cells. | 2013 Apr 1 |
3 |
| 55 |
23839822 | Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells. | 2013 Oct |
1 |
| 56 |
23897750 | Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased DNA damage and senescence. | 2013 Dec |
1 |
| 57 |
23934411 | Inhibition of ATR kinase with the selective inhibitor VE-821 results in radiosensitization of cells of promyelocytic leukaemia (HL-60). | 2013 Nov |
1 |
| 58 |
22226932 | Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1. | 2012 Mar 15 |
1 |
| 59 |
22265862 | Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling. | 2012 Jun 1 |
1 |
| 60 |
22290195 | Testosterone promotes DNA damage response under oxidative stress in prostate cancer cell lines. | 2012 Sep 15 |
3 |
| 61 |
22390926 | Targeting Werner syndrome protein sensitizes U-2 OS osteosarcoma cells to selenium-induced DNA damage response and necrotic death. | 2012 Mar 30 |
2 |
| 62 |
22525466 | Ataxia-telangiectasia mutated and the Mre11-Rad50-NBS1 complex: promising targets for radiosensitization. | 2012 |
1 |
| 63 |
22627294 | Clioquinol induces DNA double-strand breaks, activation of ATM, and subsequent activation of p53 signaling. | 2012 Sep 4 |
2 |
| 64 |
22728709 | Pharmacological inhibition of ATM by KU55933 stimulates ATM transcription. | 2012 Jun |
2 |
| 65 |
22763242 | Autophagy and reactive oxygen species modulate cytotoxicity induced by suppression of ATM kinase activity in head and neck cancer cells. | 2012 Nov |
1 |
| 66 |
22909323 | Quantitative proteomics reveal ATM kinase-dependent exchange in DNA damage response complexes. | 2012 Oct 5 |
1 |
| 67 |
22923485 | Threonine 2609 phosphorylation of the DNA-dependent protein kinase is a critical prerequisite for epidermal growth factor receptor-mediated radiation resistance. | 2012 Oct |
1 |
| 68 |
23015717 | The cellular ataxia telangiectasia-mutated kinase promotes epstein-barr virus lytic reactivation in response to multiple different types of lytic reactivation-inducing stimuli. | 2012 Dec |
2 |
| 69 |
23054561 | ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells. | 2012 Dec |
1 |
| 70 |
23058634 | Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells. | 2012 Nov 1 |
2 |
| 71 |
23185347 | Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin. | 2012 |
3 |
| 72 |
21195095 | Cadmium induced radioadaptive response via an ATM-independent H(2)S/cystathionine γ-lyase modulation. | 2011 Feb 10 |
1 |
| 73 |
21325885 | Three independent mechanisms for arrest in G2 after ionizing radiation. | 2011 Mar 1 |
2 |
| 74 |
21424556 | Antiapoptotic effects of roscovitine on camptothecin-induced DNA damage in neuroblastoma cells. | 2011 May |
1 |
| 75 |
21532626 | Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional. | 2011 Oct 13 |
2 |
| 76 |
21616090 | 5-Methoxyflavanone induces cell cycle arrest at the G2/M phase, apoptosis and autophagy in HCT116 human colon cancer cells. | 2011 Aug 1 |
1 |
| 77 |
21889946 | AT cells are not radiosensitive for simple chromosomal exchanges at low dose. | 2011 Nov 1 |
1 |
| 78 |
21937706 | An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5. | 2011 Nov |
3 |
| 79 |
21945951 | The activation of the p53 pathway by the AMP mimetic AICAR is reduced by inhibitors of the ATM or mTOR kinases. | 2011 Nov-Dec |
1 |
| 80 |
21973212 | Role for p53 in selenium-induced senescence. | 2011 Nov 9 |
1 |
| 81 |
20053781 | The ATM inhibitor KU-55933 suppresses cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt. | 2010 Jan |
2 |
| 82 |
20502937 | Activation of ataxia telangiectasia muted under experimental models and human Parkinson's disease. | 2010 Nov |
2 |
| 83 |
20615625 | Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells. | 2010 Sep 1 |
1 |
| 84 |
20978197 | Targeted radiosensitization of cells expressing truncated DNA polymerase {beta}. | 2010 Nov 1 |
1 |
| 85 |
19351839 | Inhibition of ataxia telangiectasia mutated kinase activity enhances TRAIL-mediated apoptosis in human melanoma cells. | 2009 Apr 15 |
1 |
| 86 |
19465392 | The role of DNA damage response pathways in chromosome fragility in Fragile X syndrome. | 2009 Jul |
2 |
| 87 |
19502594 | Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner. | 2009 Aug |
1 |
| 88 |
19530246 | Involvement of ATM-mediated Chk1/2 and JNK kinase signaling activation in HKH40A-induced cell growth inhibition. | 2009 Oct |
3 |
| 89 |
19544417 | Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells. | 2009 Aug |
2 |
| 90 |
19583974 | Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation. | 2009 Nov 2 |
1 |
| 91 |
19695441 | ATM-dependent hyper-radiosensitivity in mammalian cells irradiated by heavy ions. | 2009 Sep 1 |
1 |
| 92 |
19808981 | Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion. | 2009 Oct |
1 |
| 93 |
19903334 | The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation. | 2009 Nov 10 |
1 |
| 94 |
19996277 | G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells. | 2009 Dec |
1 |
| 95 |
18248856 | Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling. | 2008 Mar 1 |
2 |
| 96 |
18347191 | Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy. | 2008 Mar 15 |
2 |
| 97 |
18596239 | WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks. | 2008 Sep |
1 |
| 98 |
16983346 | HIV-1 Vpr induces ATM-dependent cellular signal with enhanced homologous recombination. | 2007 Jan 25 |
2 |
| 99 |
17283137 | Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response. | 2007 Feb 1 |
1 |
| 100 |
17371003 | Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase. | 2007 Apr 19 |
3 |