Pub. Date : 2009
PMID : 19685112
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The half-maximal activation concentrations (EC(50)) of caffeine and 4CmC for HEK-293 cells transfected with the p.R2508C mutation were 1.86 +/- 0.23 mM and 73.14 +/- 19.44 microM, while those for wild-type RYR1 were 2.62 +/- 0.23 mM and 179.31 +/- 35.23 microM, respectively. | Caffeine | ryanodine receptor 1 | Homo sapiens |
2 | CONCLUSION: We demonstrated that the transfected RYR1 mutant was more sensitive to caffeine and 4CmC than wildtype RYR1. | Caffeine | ryanodine receptor 1 | Homo sapiens |