Fadrozole

cytochrome P450 family 11 subfamily B member 2 ; Homo sapiens







8 Article(s)
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Pub. Year
#Total Relationships
1 33271294 Aldosterone synthase inhibitors for cardiovascular diseases: A comprehensive review of preclinical, clinical and in silico data. 2021 Jan 3
2 30425102 Structure of human cortisol-producing cytochrome P450 11B1 bound to the breast cancer drug fadrozole provides insights for drug design. 2019 Jan 11 2
3 28759940 Impact of Aldosterone Synthase Inhibitor FAD286 on Steroid Hormone Profile in Human Adrenocortical Cells. 2017 Sep 4
4 23322723 Structural insights into aldosterone synthase substrate specificity and targeted inhibition. 2013 Feb 2
5 23856493 Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension. 2013 Sep 1
6 19622340 Coexpression of CYP11B2 or CYP11B1 with adrenodoxin and adrenodoxin reductase for assessing the potency and selectivity of aldosterone synthase inhibitors. 2009 Nov 1 2
7 16685193 Can the dextroenantiomer of the aromatase inhibitor fadrozole be useful for clinical investigation of aldosterone-synthase inhibition? 2006 Jun 2
8 15985365 The adrenocortical tumor cell line NCI-H295R as an in vitro screening system for the evaluation of CYP11B2 (aldosterone synthase) and CYP11B1 (steroid-11beta-hydroxylase) inhibitors. 2005 Aug 1