pralidoxime

acetylcholinesterase (Cartwright blood group) ; Homo sapiens







69 Article(s)
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Pub. Year
#Total Relationships
1 33960866 Acute phenthoate self-poisoning: a prospective case series. 2022 Feb 2
2 34989015 CON: Oximes should not be used routinely in organophosphorus insecticide poisoning. 2022 Jan 5 1
3 35023196 Pro: Oximes should be used routinely in organophosphate poisoning. 2022 Jan 12 2
4 31879781 Characterization of Cholinesterases From Multiple Large Animal Species for Medical Countermeasure Development Against Chemical Warfare Nerve Agents. 2020 Mar 1 1
5 32267631 A novel high-performance liquid chromatography with diode array detector method for the simultaneous quantification of the enzyme-reactivating oximes obidoxime, pralidoxime, and HI-6 in human plasma. 2020 Jul 2
6 32645360 Glycosylated-imidazole aldoximes as reactivators of pesticides inhibited AChE: Synthesis and in-vitro reactivation study. 2020 Nov 1
7 32898602 Surface modification of pralidoxime chloride-loaded solid lipid nanoparticles for enhanced brain reactivation of organophosphorus-inhibited AChE: Pharmacokinetics in rat. 2020 Nov 1
8 31100277 Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure. 2019 Aug 1 2
9 28328690 The First Use of Pralidoxime in a Child With Rivastigmine Poisoning. 2018 Oct 1
10 29482737 Kinetic analysis of oxime-assisted reactivation of human, Guinea pig, and rat acetylcholinesterase inhibited by the organophosphorus pesticide metabolite phorate oxon (PHO). 2018 Feb 1
11 29577198 Study of the Oxime-induced Reactivation of Acetyl- and Butyrylcholinesterase of Human with Inhibition of Organophosphorus Insecticide In Vitro. 2018 Mar 1
12 28106328 On the Influence of the Protonation States of Active Site Residues on AChE Reactivation: A QM/MM Approach. 2017 Apr 4 2
13 26210933 Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase. 2016 Feb 26 1
14 26558640 Design, synthesis, and evaluation of guanylhydrazones as potential inhibitors or reactivators of acetylcholinesterase. 2016 Dec 2
15 27062893 Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents. 2016 Nov 25 2
16 27102179 Efficacy of Recommended Prehospital Human Equivalent Doses of Atropine and Pralidoxime Against the Toxic Effects of Carbamate Poisoning in the Hartley Guinea Pig. 2016 May 1
17 27179675 A liquid chromatography tandem mass spectrometric method on in vitro nerve agents poisoning characterization and reactivator efficacy evaluation by determination of specific peptide adducts in acetylcholinesterase. 2016 Jun 10 1
18 25712411 Variable response of cholinesterase activities following human exposure to different types of organophosphates. 2015 Jul 2
19 26165232 A fluorescence assay for measuring acetylcholinesterase activity in rat blood and a human neuroblastoma cell line (SH-SY5Y). 2015 Nov-Dec 1
20 23527625 Reactivation steps by 2-PAM of tabun-inhibited human acetylcholinesterase: reducing the computational cost in hybrid QM/MM methods. 2014 2
21 25672327 Regional preparedness for mass acetylcholinesterase inhibitor poisoning through plans for stockpiling and interhospital sharing of pralidoxime. 2014 Fall 2
22 23461011 [Studying kinetics of oxime-induced reactivation of malathion-inhibited cholinesterase]. 2013 1
23 23735753 Kinin-B2 receptor exerted neuroprotection after diisopropylfluorophosphate-induced neuronal damage. 2013 Sep 5 1
24 23789829 In silico pharmacophore modeling on known pyridinium oxime reactivators of cyclosarin (GF) inhibited AChE to Aid discovery of potential, more efficacious novel non-oxime reactivators. 2013 Sep 1
25 23962483 Investigation of kinetic interactions between approved oximes and human acetylcholinesterase inhibited by pesticide carbamates. 2013 Dec 5 1
26 24157926 Affinities of bispyridinium non-oxime compounds to [(3)H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length. 2013 Dec 5 1
27 22360473 Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents. 2012 May 15 1
28 20027669 Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides. 2011 Jul 2
29 21569834 A cembranoid protects acute hippocampal slices against paraoxon neurotoxicity. 2011 Oct 1
30 21673941 In vitro ability of currently available oximes to reactivate organophosphate pesticide-inhibited human acetylcholinesterase and butyrylcholinesterase. 2011 1
31 21983245 Potential of two new oximes in reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by organophosphate compounds: an in vitro study. 2011 Dec 1
32 20227398 Novel oximes as blood-brain barrier penetrating cholinesterase reactivators. 2010 Sep 6 1
33 20370537 Reactivation of immobilized acetylcholinesterase-tabun complex by pralidoxime, its isomers, and homologs. 2010 Jun 1
34 20406208 In vitro reactivating effects of standard and newly developed oximes on malaoxon-inhibited mouse brain acetylcholinesterase. 2010 Sep 1
35 20655881 Y124 at the peripheral anionic site is important for the reactivation of nerve agent-inhibited acetylcholinesterase by H oximes. 2010 Nov 1 1
36 19433070 Extreme variability in the formation of chlorpyrifos oxon (CPO) in patients poisoned by chlorpyrifos (CPF). 2009 Sep 1 1
37 19564902 Pralidoxime in acute organophosphorus insecticide poisoning--a randomised controlled trial. 2009 Jun 30 3
38 19651196 Medical treatment of acute poisoning with organophosphorus and carbamate pesticides. 2009 Oct 28 1
39 18617161 Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro. 2008 Sep 25 1
40 18675298 The influence of the support nature on the kinetics parameters, inhibition constants and reactivation of immobilized acetylcholinesterase. 2008 Nov 1 1
41 18676153 Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase. 2008 Sep 1 1
42 16904807 Simulation of cholinesterase status at different scenarios of nerve agent exposure. 2007 Apr 20 2
43 17096373 An unusual cause of atrial fibrillation: exposure to insecticides. 2007 Jan 1
44 17503257 Potency of five structurally different acetylcholinesterase reactivators to reactivate human brain cholinesterases inhibited by cyclosarin. 2007 Jun-Aug 1
45 17590326 Comparison of pesticide sensitivity by electrochemical test based on acetylcholinesterase biosensor. 2007 Sep 30 1
46 18254274 Evaluation of potency of known oximes (pralidoxime, trimedoxime, HI-6, methoxime, obidoxime) to in vitro reactivate acetylcholinesterase inhibited by pesticides (chlorpyrifos and methylchlorpyrifos) and nerve agent (Russian VX). 2007 2
47 16971069 Hydrolysis of an acetylthiocholine by pralidoxime iodide (2-PAM). 2006 Oct 25 2
48 15904945 Evaluation of oxime efficacy in nerve agent poisoning: development of a kinetic-based dynamic model. 2005 Dec 15 2
49 16119192 In vitro reactivation of sarin-inhibited brain acetylcholinesterase from different species by various oximes. 2005 Jun 1
50 16119193 A new group of monoquaternary reactivators of acetylcholinesterase inhibited by nerve agents. 2005 Jun 1