Title : Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides.

Pub. Date : 2011 Jul

PMID : 20027669






2 Functional Relationships(s)
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1 Commercial AChE reactivators (e.g. pralidoxime, HI-6, obidoxime, trimedoxime, methoxime) were originally developed for other members of the organophosphate family, such as nerve agents (e.g. sarin, soman, tabun, VX). pralidoxime acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Pralidoxime, HI-6, and methoxime were found to be weak reactivators of OPP-inhibited AChE. pralidoxime acetylcholinesterase (Cartwright blood group) Homo sapiens