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31866476 | Natural products targeting the PI3K-Akt-mTOR signaling pathway in cancer: A novel therapeutic strategy. | 2022 May |
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34811774 | Structure and pro-inflammatory activities of bran polysaccharides from a novel wheat kernel. | 2022 Jan |
2 |
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35338148 | Comprehensive characterization of PTEN mutational profile in a series of 34,129 colorectal cancers. | 2022 Mar 25 |
1 |
| 4 |
35525984 | AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatology. | 2022 May 7 |
1 |
| 5 |
33485488 | Investigating mutations at the hotspot position of the ERBB2 and screening for the novel lead compound to treat breast cancer - a computational approach. | 2021 |
1 |
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33788710 | Autophagy Induction by α-Santalol in Human Prostate Cancer Cells. | 2021 Mar |
1 |
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34065746 | Endosomal mTORC2 Is Required for Phosphoinositide-Dependent AKT Activation in Platelet-Derived Growth Factor-Stimulated Glioma Cells. | 2021 May 16 |
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34073143 | Resveratrol Attenuates the Proliferation of Prostatic Stromal Cells in Benign Prostatic Hyperplasia by Regulating Cell Cycle Progression, Apoptosis, Signaling Pathways, BPH Markers, and NF- κB Activity. | 2021 May 31 |
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34240493 | Persistent activation of the mammalian target of rapamycin signalling pathway in cutaneous squamous cell carcinomas in cats. | 2021 Dec |
2 |
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34421588 | Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation. | 2021 |
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34440716 | Human Vascular Smooth Muscle Function and Oxidative Stress Induced by NADPH Oxidase with the Clinical Implications. | 2021 Jul 31 |
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34515904 | Management of hormone receptor-positive, human epidermal growth factor 2-negative metastatic breast cancer. | 2021 Nov |
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34739932 | Investigation on the mechanisms of biochanin A alleviate PM10-induced acute pulmonary cell injury. | 2021 Nov 2 |
2 |
| 14 |
34977875 | Altering phosphoinositides in high-fat diet-associated prostate tumor xenograft growth. | 2021 Dec |
2 |
| 15 |
31605740 | Targeting L-type amino acid transporter 1 in innate and adaptive T cells efficiently controls skin inflammation. | 2020 Jan |
1 |
| 16 |
31648572 | Radiosensitizing Potential of Curcumin in Different Cancer Models. | 2020 |
1 |
| 17 |
31666206 | Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2. | 2020 Jan 1 |
1 |
| 18 |
31694485 | Tryptophanyl-tRNA synthetase (WARS) expression in uveal melanoma - possible contributor during uveal melanoma progression. | 2020 Mar |
2 |
| 19 |
31734375 | Low-level laser therapy induces human umbilical vascular endothelial cell proliferation, migration and tube formation through activating the PI3K/Akt signaling pathway. | 2020 May |
1 |
| 20 |
31742349 | Protective effects of human umbilical cord mesenchymal stem cell-derived conditioned medium on ovarian damage. | 2020 Jun 11 |
1 |
| 21 |
31742778 | Ganoderic Acid A exerts the cytoprotection against hypoxia-triggered impairment in PC12 cells via elevating microRNA-153. | 2020 Mar |
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| 22 |
31743544 | Anti-inflammatory effects of doxepin hydrochloride against LPS-induced C6-glioma cell inflammatory reaction by PI3K-mediated Akt signaling. | 2020 Feb |
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31794514 | Transcription-independent Induction of ERBB1 through Hypoxia-inducible Factor 2A Provides Cardioprotection during Ischemia and Reperfusion. | 2020 Apr |
1 |
| 24 |
31837357 | MUC13 promotes intrahepatic cholangiocarcinoma progression via EGFR/PI3K/AKT pathways. | 2020 Apr |
1 |
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31840737 | Isoliquiritigenin inhibits the proliferation, migration and metastasis of Hep3B cells via suppressing cyclin D1 and PI3K/AKT pathway. | 2020 Jan 31 |
1 |
| 26 |
31884041 | Phosphoproteomic analysis reveals Akt isoform-specific regulation of cytoskeleton proteins in human temporal lobe epilepsy with hippocampal sclerosis. | 2020 Mar |
1 |
| 27 |
31889352 | Involvement of intracellular caveolin-1 distribution in the suppression of antigen-induced mast cell activation by cationic liposomes. | 2020 Apr |
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| 28 |
31947601 | Crosstalk between PTEN/PI3K/Akt Signalling and DNA Damage in the Oocyte: Implications for Primordial Follicle Activation, Oocyte Quality and Ageing. | 2020 Jan 14 |
2 |
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31955800 | Dysregulated Expression of Phosphorylated Epidermal Growth Factor Receptor and Phosphatase and Tensin Homologue in Canine Cutaneous Papillomas and Squamous Cell Carcinomas. | 2020 Jan |
2 |
| 30 |
31957818 | MicroRNA-149 suppresses the malignant phenotypes of ovarian cancer via downregulation of MSI2 and inhibition of PI3K/AKT pathway. | 2020 Jan |
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| 31 |
31989480 | Mangiferin ameliorates placental oxidative stress and activates PI3K/Akt/mTOR pathway in mouse model of preeclampsia. | 2020 Feb |
2 |
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32031889 | MK-2206 and Standard Neoadjuvant Chemotherapy Improves Response in Patients With Human Epidermal Growth Factor Receptor 2-Positive and/or Hormone Receptor-Negative Breast Cancers in the I-SPY 2 Trial. | 2020 Apr 1 |
1 |
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32036474 | Exploitation of a novel phenothiazine derivative for its anti-cancer activities in malignant glioblastoma. | 2020 Apr |
1 |
| 34 |
32052470 | Melatonin enhances thrombopoiesis through ERK1/2 and Akt activation orchestrated by dual adaptor for phosphotyrosine and 3-phosphoinositides. | 2020 Apr |
2 |
| 35 |
32096172 | MiR-19 enhances pancreatic cancer progression by targeting PTEN through PI3K/AKT signaling pathway. | 2020 Feb |
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| 36 |
32109492 | MiR-139-5p/SLC7A11 inhibits the proliferation, invasion and metastasis of pancreatic carcinoma via PI3K/Akt signaling pathway. | 2020 Jun 1 |
1 |
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32372865 | Ginsenoside Rb1 and Rb2 upregulate Akt/mTOR signaling-mediated muscular hypertrophy and myoblast differentiation. | 2020 May |
1 |
| 38 |
32404282 | Heregulin controls ERα and HER2 signaling in mammospheres of ERα-positive breast cancer cells and interferes with the efficacy of molecular targeted therapy. | 2020 Jul |
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32427739 | Geraniin inhibits proliferation and induces apoptosis through inhibition of phosphatidylinositol 3-kinase/Akt pathway in human colorectal cancer in vitro and in vivo. | 2020 Jul |
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| 40 |
32743074 | Increased PIP3 activity blocks nanoparticle mRNA delivery. | 2020 Jul |
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| 41 |
30574817 | Investigational PI3K/AKT/mTOR inhibitors in development for endometrial cancer. | 2019 Feb |
2 |
| 42 |
30696066 | Mettl3 Regulates Osteogenic Differentiation and Alternative Splicing of Vegfa in Bone Marrow Mesenchymal Stem Cells. | 2019 Jan 28 |
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30735452 | lncRNA GAS5 restrains CCl4-induced hepatic fibrosis by targeting miR-23a through the PTEN/PI3K/Akt signaling pathway. | 2019 Apr 1 |
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| 44 |
30987931 | Phosphoinositide spatially free AKT/PKB activation to all membrane compartments. | 2019 May |
2 |
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30993090 | Induction of Apoptosis Scutellaria baicalensis Georgi Root Extract by Inactivation of the Phosphatidyl Inositol 3-kinase/Akt Signaling Pathway in Human Leukemia U937 Cells. | 2019 Mar |
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| 46 |
31158782 | Insulin-like growth factor-1 directly mediates expression of mitochondrial uncoupling protein 3 via forkhead box O4. | 2019 Jun - Aug |
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| 47 |
31178679 | Therapeutic Potential of Oxytocin in Atherosclerotic Cardiovascular Disease: Mechanisms and Signaling Pathways. | 2019 |
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| 48 |
31268205 | Tanshinone IIA combined with cisplatin synergistically inhibits non-small-cell lung cancer in vitro and in vivo via down-regulating the phosphatidylinositol 3-kinase/Akt signalling pathway. | 2019 Sep |
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| 49 |
31541079 | DPEP1 is a direct target of miR-193a-5p and promotes hepatoblastoma progression by PI3K/Akt/mTOR pathway. | 2019 Sep 20 |
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| 50 |
31546901 | Prognostic and Predictive Implications of PTEN in Breast Cancer: Unfulfilled Promises but Intriguing Perspectives. | 2019 Sep 19 |
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