Pub. Date : 2020 Apr
PMID : 32052470
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Melatonin enhances thrombopoiesis through ERK1/2 and Akt activation orchestrated by dual adaptor for phosphotyrosine and 3-phosphoinositides. | Phosphatidylinositols | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Interestingly, in addition to the direct regulation of Akt signaling by its upstream phosphoinositide 3-kinase (PI3K), ERK1/2 signaling is also regulated by PI3K via its effector, dual adaptor for phosphotyrosine and 3-phosphoinositides (DAPP1), in megakaryocytes after MT treatment. | Phosphatidylinositols | AKT serine/threonine kinase 1 | Homo sapiens |