| 1 |
34731371 | mTOR inhibitor PP242 increases antitumor activity of sulforaphane by blocking Akt/mTOR pathway in esophageal squamous cell carcinoma. | 2022 Jan |
3 |
| 2 |
32642408 | RICTOR/mTORC2 affects tumorigenesis and therapeutic efficacy of mTOR inhibitors in esophageal squamous cell carcinoma. | 2020 Jun |
2 |
| 3 |
29692710 | PP242 Counteracts Glioblastoma Cell Proliferation, Migration, Invasiveness and Stemness Properties by Inhibiting mTORC2/AKT. | 2018 |
1 |
| 4 |
29849119 | mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy. | 2018 Sep |
3 |
| 5 |
28612529 | [The Mechanism of Combination using mTORC1/2 Inhibitor and Imatinib to Suppress Cell Proliferation of Ph +ALL Cell Line]. | 2017 Mar |
1 |
| 6 |
26548560 | PP242 suppresses bladder cancer cell proliferation and migration through deactivating the mammalian target of rapamycin complex 2/AKT1 signaling pathway. | 2016 Jan |
3 |
| 7 |
26776341 | Effective targeting of colorectal cancer cells using TORC1/2 kinase inhibitors in vitro and in vivo. | 2016 Feb |
1 |
| 8 |
26956871 | Recurrent neomorphic mutations of MTOR in central nervous system and testicular germ cell tumors may be targeted for therapy. | 2016 Jun |
2 |
| 9 |
27566137 | mTORC1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in IPF fibroblasts. | 2016 Dec |
1 |
| 10 |
25535978 | The antileukemia roles of PP242 alone or in combination with daunorubicin in acute leukemia. | 2015 Apr |
1 |
| 11 |
25035961 | PP242 suppresses cell proliferation, metastasis, and angiogenesis of gastric cancer through inhibition of the PI3K/AKT/mTOR pathway. | 2014 Nov |
3 |
| 12 |
23437362 | Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells. | 2013 |
1 |
| 13 |
23528835 | Sustained overexpression of Redd1 leads to Akt activation involved in cell survival. | 2013 Aug 19 |
2 |
| 14 |
23838676 | A dual mTORC1 and mTORC2 inhibitor shows antitumor activity in esophageal squamous cell carcinoma cells and sensitizes them to cisplatin. | 2013 Oct |
2 |
| 15 |
23991179 | Combination of mTOR and EGFR kinase inhibitors blocks mTORC1 and mTORC2 kinase activity and suppresses the progression of colorectal carcinoma. | 2013 |
4 |
| 16 |
22476852 | Targeting of mTORC2 prevents cell migration and promotes apoptosis in breast cancer. | 2012 Aug |
1 |
| 17 |
20686120 | Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor. | 2010 Nov 25 |
1 |