Title : Sustained overexpression of Redd1 leads to Akt activation involved in cell survival.

Pub. Date : 2013 Aug 19

PMID : 23528835






2 Functional Relationships(s)
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1 Perifosine and PP242, selective inhibitors of Akt and mTORC1/2, respectively, efficiently suppressed the Akt phosphorylation that was induced by the sustained overexpression of Redd1 and increased the sensitivity of the cells to cisplatin. PP242 AKT serine/threonine kinase 1 Homo sapiens
2 Perifosine and PP242, selective inhibitors of Akt and mTORC1/2, respectively, efficiently suppressed the Akt phosphorylation that was induced by the sustained overexpression of Redd1 and increased the sensitivity of the cells to cisplatin. PP242 AKT serine/threonine kinase 1 Homo sapiens