matrine

AKT serine/threonine kinase 1 ; Homo sapiens







23 Article(s)
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1 35242238 Matrine exerts antitumor activity in cervical cancer by protective autophagy via the Akt/mTOR pathway in vitro and in vivo. 2022 Apr 2
2 34366869 Matrine Impairs Platelet Function and Thrombosis and Inhibits ROS Production. 2021 1
3 32862598 Matrine induces apoptosis and autophagy in human lung adenocarcinoma cells via upregulation of Cavin3 and suppression of PI3K/AKT pathway. 2020 May-Jun 2
4 33000249 Matrine exerts anti‑breast cancer activity by mediating apoptosis and protective autophagy via the AKT/mTOR pathway in MCF‑7 cells. 2020 Nov 5
5 33125118 [Corrigendum] The specific killing effect of matrine on castration‑resistant prostate cancer cells by targeting the Akt/FoxO3a signaling pathway. 2020 Dec 1
6 30988763 Matrine inhibits the proliferation of pituitary tumor cells by decreasing Foxo3a phosphorylation and promoting Foxo3a nuclear localization. 2019 May 2
7 31340906 [Matrine inhibits proliferation and promotes autophagy and apoptosis in non-small cell lung cancer cells by deactivating PI3K/AKT/mTOR pathway]. 2019 Jul 30 4
8 31452769 Matrine induces apoptosis in acute myeloid leukemia cells by inhibiting the PI3K/Akt/mTOR signaling pathway. 2019 Sep 1
9 31460901 Role and mechanism of matrine alone and combined with acitretin for HaCaT cells and psoriasis-like murine models. 2019 Sep 5 1
10 31579406 Downregulated miR-21 mediates matrine-induced apoptosis via the PTEN/Akt signaling pathway in FTC-133 human follicular thyroid cancer cells. 2019 Oct 2
11 31615459 Autophagy inhibition enhances Matrine derivative MASM induced apoptosis in cancer cells via a mechanism involving reactive oxygen species-mediated PI3K/Akt/mTOR and Erk/p38 signaling. 2019 Oct 15 1
12 31634459 Matrine pre-treatment suppresses AGEs- induced HCSMCs fibrotic responses by regulating Poldip2/mTOR pathway. 2019 Dec 15 1
13 31801708 [Matrine suppresses stemness of hepatocellular carcinoma cells by regulating β-catenin signaling pathway]. 2019 Oct 30 1
14 29130495 Matrine reversed multidrug resistance of breast cancer MCF-7/ADR cells through PI3K/AKT signaling pathway. 2018 May 1
15 29845189 Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelial‑mesenchymal transition. 2018 Jul 2
16 30079478 Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway. 2018 Sep 2
17 30127885 Matrine inhibits TPC-1 human thyroid cancer cells via the miR-21/PTEN/Akt pathway. 2018 Sep 1
18 27650610 Matrine Suppresses Proliferation and Invasion of SGC7901 Cells through Inactivation of PI3K/Akt/uPA Pathway. 2016 Sep 3
19 25371071 Matrine inhibits the growth and induces apoptosis of osteosarcoma cells in vitro by inactivating the Akt pathway. 2015 Mar 1
20 25572156 Matrine inhibits the invasive properties of human glioma cells by regulating epithelial‑to‑mesenchymal transition. 2015 May 2
21 24452711 Matrine inhibits proliferation and induces apoptosis of human colon cancer LoVo cells by inactivating Akt pathway. 2014 2
22 23912239 Matrine activates PTEN to induce growth inhibition and apoptosis in V600EBRAF harboring melanoma cells. 2013 Jul 31 1
23 24287900 Blocking autophagic flux enhances matrine-induced apoptosis in human hepatoma cells. 2013 Nov 25 1