Title : Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelial‑mesenchymal transition.

Pub. Date : 2018 Jul

PMID : 29845189






2 Functional Relationships(s)
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1 Furthermore, matrine can increase phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN) expression and reduce phosphorylated-protein kinase B (Akt) levels. matrine AKT serine/threonine kinase 1 Homo sapiens
2 In conclusion, these results suggested that matrine is a potential therapeutic agent that can suppress cancer-associated invasion and migration via PTEN/Akt-dependent inhibition of EMT. matrine AKT serine/threonine kinase 1 Homo sapiens