| 1 |
34376311 | A targeted approach to phosphoinositide-3-kinase/Akt/mammalian target of rapamycin-induced hyperglycemia. | 2022 Feb |
1 |
| 2 |
34739190 | Micro ribonucleic acid-363 regulates the phosphatidylinositol 3-kinase/threonine protein kinase axis by targeting NOTCH1 and forkhead box C2, leading to hepatic glucose and lipids metabolism disorder in type 2 diabetes mellitus. | 2022 Feb |
1 |
| 3 |
34791822 | AKT1/HK2 Axis-mediated Glucose Metabolism: A Novel Therapeutic Target of Sulforaphane in Bladder Cancer. | 2022 Feb |
1 |
| 4 |
34994492 | Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance. | 2022 Feb 3 |
1 |
| 5 |
35069879 | CRNDE silencing promotes apoptosis and enhances cisplatin sensitivity of colorectal carcinoma cells by inhibiting the Akt/mTORC1-mediated Warburg effect. | 2022 Feb |
1 |
| 6 |
35163310 | Enhanced Ca2+ Entry Sustains the Activation of Akt in Glucose Deprived SH-SY5Y Cells. | 2022 Jan 26 |
3 |
| 7 |
35186790 | Interferon Alpha Induces Cellular Autophagy and Modulates Hepatitis B Virus Replication. | 2022 |
1 |
| 8 |
35192961 | Comorbidity of osteoporosis and Alzheimer's disease: Is `AKT `-ing on cellular glucose uptake the missing link? | 2022 Apr |
1 |
| 9 |
35217361 | Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway. | 2022 Apr 16 |
1 |
| 10 |
35232557 | MiR-153-3p reduces extracellular matrix accumulation in high glucose-stimulated human glomerular mesangial cells via targeting PAQR3 in diabetic nephropathy. | 2022 Jan |
1 |
| 11 |
35241480 | Signaling Pathways That Drive 18F-FDG Accumulation in Cancer. | 2022 May |
1 |
| 12 |
35323624 | Glucose Counteracts Isoprenaline Effects on Ion Channel Functions in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. | 2022 Mar 4 |
2 |
| 13 |
35330934 | Akt: A Potential Drug Target for Metabolic Syndrome. | 2022 |
1 |
| 14 |
35383148 | Akt-GSK3β-mPTP pathway regulates the mitochondrial dysfunction contributing to odontoblasts apoptosis induced by glucose oxidative stress. | 2022 Apr 5 |
2 |
| 15 |
35392289 | Activating Effects of the Bioactive Compounds From Coffee By-Products on FGF21 Signaling Modulate Hepatic Mitochondrial Bioenergetics and Energy Metabolism in vitro. | 2022 |
1 |
| 16 |
35401165 | Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis. | 2022 |
1 |
| 17 |
35402865 | Calcineurin/NFATc2 and PI3K/AKT signaling maintains β-cell identity and function during metabolic and inflammatory stress. | 2022 Apr 15 |
1 |
| 18 |
35405148 | Meroterpenoids containing benzopyran or benzofuran motif from Ganoderma cochlear. | 2022 Jul |
2 |
| 19 |
35414507 | GATA2/FGF21 Axis Regulates the Effects of High Glucose on the Apoptosis, Autophagy and Oxidative Stress of Human Umbilical Vein Endothelial Cell via PI3K/AKT/mTOR Pathway. | 2022 Mar |
1 |
| 20 |
35415942 | Effect of Glut-1 and HIF-1α double knockout by CRISPR/CAS9 on radiosensitivity in laryngeal carcinoma via the PI3K/Akt/mTOR pathway. | 2022 May |
1 |
| 21 |
35440095 | Leukemia inhibitory factor drives glucose metabolic reprogramming to promote breast tumorigenesis. | 2022 Apr 19 |
1 |
| 22 |
35462099 | CaMKII and Kalirin, a Rac1-GEF, regulate Akt phosphorylation involved in contraction-induced glucose uptake in skeletal muscle cells. | 2022 Jun 25 |
2 |
| 23 |
35500642 | Astaxanthin ameliorates hyperglycemia induced inflammation via PI3K/Akt-NF-κB signaling in ARPE-19 cells and diabetic rat retina. | 2022 Jul 5 |
1 |
| 24 |
35524821 | Canonical insulin signaling is not significantly impaired in early stages of depression. | 2022 May 7 |
2 |
| 25 |
35584604 | TRPC5OS induces tumorigenesis by increasing ENO1-mediated glucose uptake in breast cancer. | 2022 Aug |
2 |
| 26 |
35605918 | A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling pathways in HepG2 cells. | 2022 Sep 15 |
1 |
| 27 |
32745838 | Polyphenol-rich extract of Zhenjiang aromatic vinegar ameliorates high glucose-induced insulin resistance by regulating JNK-IRS-1 and PI3K/Akt signaling pathways. | 2021 Jan 15 |
3 |
| 28 |
32900356 | Quercetin Inhibits AQP1 Translocation in High-Glucose-Cultured SRA01/04 Cells Through PI3K/Akt/mTOR Pathway. | 2021 Oct 25 |
2 |
| 29 |
33138992 | Decabromodiphenyl ether disturbs hepatic glycolipid metabolism by regulating the PI3K/AKT/GLUT4 and mTOR/PPARγ/RXRα pathway in mice and L02 cells. | 2021 Apr 1 |
1 |
| 30 |
33161133 | Inorganic nitrite alters mitochondrial dynamics without overt changes in cell death and mitochondrial respiration in cardiomyoblasts under hyperglycemia. | 2021 Feb |
1 |
| 31 |
33270355 | Activation of Akt-dependent Nrf2/ARE pathway by restoration of Brg-1 remits high glucose-induced oxidative stress and ECM accumulation in podocytes. | 2021 Mar |
1 |
| 32 |
33400924 | Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53. | 2021 Feb 4 |
1 |
| 33 |
33435282 | Plant Extracts for Type 2 Diabetes: From Traditional Medicine to Modern Drug Discovery. | 2021 Jan 9 |
1 |
| 34 |
33441223 | [Down-regulation of PHLPP1 expression ameliorates high glucose-induced autophagy inhibition and apoptosis promotion of podocytes by activating PI3K/AKT/mTOR pathway]. | 2021 Jan |
1 |
| 35 |
33534194 | Purification of Gekko Small Peptide Fraction and Its Effect of Inducing Apoptosis of EC 9706 Esophageal Cancer Cells by Inhibiting PI3K/Akt/GLUT1 Signaling Pathway. | 2021 Mar |
1 |
| 36 |
33608702 | Identification of Circulating hsa_circ_0063425 and hsa_circ_0056891 as Novel Biomarkers for Detection of Type 2 Diabetes. | 2021 Jun 16 |
1 |
| 37 |
33659881 | Signaling Heterogeneity is Defined by Pathway Architecture and Intercellular Variability in Protein Expression. | 2021 Feb 19 |
1 |
| 38 |
33660027 | Lithium enhances exercise-induced glycogen breakdown and insulin-induced AKT activation to facilitate glucose uptake in rodent skeletal muscle. | 2021 Apr |
2 |
| 39 |
33716662 | Integration of Nutrient Sensing in Fish Hypothalamus. | 2021 |
1 |
| 40 |
33723221 | PER1 suppresses glycolysis and cell proliferation in oral squamous cell carcinoma via the PER1/RACK1/PI3K signaling complex. | 2021 Mar 15 |
1 |
| 41 |
33760124 | HK2 is associated with the Warburg effect and proliferation in liver cancer: Targets for effective therapy with glycyrrhizin. | 2021 May |
2 |
| 42 |
33843989 | Paracrine interleukin-8 affects mesenchymal stem cells through the Akt pathway and enhances human umbilical vein endothelial cell proliferation and migration. | 2021 May 28 |
1 |
| 43 |
33855046 | Butyrate Suppresses Glucose Metabolism of Colorectal Cancer Cells via GPR109a-AKT Signaling Pathway and Enhances Chemotherapy. | 2021 |
1 |
| 44 |
33872751 | Glucose starvation greatly enhances antiproliferative and antiestrogenic potency of oligomycin A in MCF-7 breast cancer cells. | 2021 Jul |
1 |
| 45 |
33967958 | Pathological Hyperinsulinemia and Hyperglycemia in the Impaired Glucose Tolerance Stage Mediate Endothelial Dysfunction Through miR-21, PTEN/AKT/eNOS, and MARK/ET-1 Pathways. | 2021 |
1 |
| 46 |
34007449 | Effect of oxymatrine on liver gluconeogenesis is associated with the regulation of PEPCK and G6Pase expression and AKT phosphorylation. | 2021 Jul |
1 |
| 47 |
34029286 | Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway. | 2021 Jul 7 |
1 |
| 48 |
34073781 | β-Sitosterol-D-Glucopyranoside Mimics Estrogenic Properties and Stimulates Glucose Utilization in Skeletal Muscle Cells. | 2021 May 24 |
1 |
| 49 |
34119651 | Review: Schistosoma mansoni phosphatidylinositol 3 kinase (PI3K)/Akt/mechanistic target of rapamycin (mTOR) signaling pathway. | 2021 Oct-Dec |
1 |
| 50 |
34137729 | A breakthrough-like effect of metformin reduces peripheral resistance to triiodothyronine in euthyroid, non-insulin-resistant, type 2 diabetic patients. | 2021 Jul 21 |
1 |