Oxygen

NAD(P)H quinone dehydrogenase 1 ; Homo sapiens







38 Article(s)
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1 33652166 DT-diaphorase triggered theranostic nanoparticles induce the self-burst of reactive oxygen species for tumor diagnosis and treatment. 2021 Apr 15 1
2 34691356 Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells. 2021 2
3 31968140 Modulation of Nqo1 activity intercepts anoikis resistance and reduces metastatic potential of hepatocellular carcinoma. 2020 Apr 2
4 32007910 Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone. 2020 Feb 1
5 32483451 Advanced biomimetic nanoreactor for specifically killing tumor cells through multi-enzyme cascade. 2020 2
6 33214574 DNA damage induced by KP372-1 hyperactivates PARP1 and enhances lethality of pancreatic cancer cells with PARP inhibition. 2020 Nov 19 1
7 31251022 Azoreductase-Responsive Metal-Organic Framework-Based Nanodrug for Enhanced Cancer Therapy via Breaking Hypoxia-induced Chemoresistance. 2019 Jul 24 2
8 26698668 Bach1 differentially regulates distinct Nrf2-dependent genes in human venous and coronary artery endothelial cells adapted to physiological oxygen levels. 2016 Mar 1
9 27966538 NQO1 inhibits proteasome-mediated degradation of HIF-1α. 2016 Dec 14 3
10 25590809 NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone. 2015 Jan 15 2
11 25517035 The study of NADPH-dependent flavoenzyme-catalyzed reduction of benzo[1,2-c]1,2,5-oxadiazole N-oxides (benzofuroxans). 2014 Dec 15 1
12 23874855 Mitochondrial function in human neuroblastoma cells is up-regulated and protected by NQO1, a plasma membrane redox enzyme. 2013 1
13 22532167 An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis. 2012 Jun 15 1
14 23109831 NAD(P)H:quinone oxidoreductase 1 (NQO1) P187S polymorphism and prostate cancer risk in Caucasians. 2012 2
15 18253865 Association of NAD(P)H:quinone oxidoreductase 1 polymorphism and Alzheimer's disease in Chinese. 2008 Mar 2
16 16517059 Ascorbic acid differentially modulates the induction of heme oxygenase-1, NAD(P)H:quinone oxidoreductase 1 and glutathione S-transferase Ya by As(3+), Cd(2+) and Cr(6+). 2007 Feb 8 2
17 17396564 [Energotropic, antihypoxic, and antioxidative effects of flavonoids]. 2007 1
18 16790533 A potential role for cyclized quinones derived from dopamine, DOPA, and 3,4-dihydroxyphenylacetic acid in proteasomal inhibition. 2006 Sep 1
19 15047111 Role of nicotinamide quinone oxidoreductase 1 (NQO1) in protection against toxicity of electrophiles and reactive oxygen intermediates. 2004 2
20 15102952 NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger. 2004 May 2
21 15476858 Contribution of NAD(P)H:quinone oxidoreductase 1 to protection against carcinogenesis, and regulation of its gene by the Nrf2 basic-region leucine zipper and the arylhydrocarbon receptor basic helix-loop-helix transcription factors. 2004 Nov 2 2
22 15590400 NQO1 C609T polymorphism in distinct entities of pediatric hematologic neoplasms. 2004 Dec 2
23 12588957 NAD(P)H: quinone oxidoreductase 1 expression in kidney podocytes. 2003 Mar 1
24 11809856 Differential gene expression of NAD(P)H:quinone oxidoreductase and NRH:quinone oxidoreductase in human hepatocellular and biliary tissue. 2002 Feb 1
25 9762350 Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase. 1998 1
26 9163701 Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity. 1997 May 1
27 7551811 Superoxide dismutase and catalase enhance autoxidation during one-electron reduction of aminochrome by NADPH-cytochrome P-450 reductase. 1995 Feb 2
28 7620830 Active oxygen generated in the process of carcinogen metabolism can induce oxidative damage in nuclei. 1995 Mar 1
29 8593536 Effects of superoxide dismutase and catalase during reduction of adrenochrome by DT-diaphorase and NADPH-cytochrome P450 reductase. 1995 Oct 1
30 8031841 The protective effect of superoxide dismutase and catalase against formation of reactive oxygen species during reduction of cyclized norepinephrine ortho-quinone by DT-diaphorase. 1994 Jul 6 3
31 8082230 Superoxide dismutase and catalase prevent the formation of reactive oxygen species during reduction of cyclized dopa ortho-quinone by DT-diaphorase. 1994 Nov 2
32 8195022 Relative importance of DT-diaphorase and hypoxia in the bioactivation of EO9 by human lung tumor cell lines. 1994 May 15 1
33 8375015 NAD(P)H:quinone oxidoreductase1 (DT-diaphorase) expression in normal and tumor tissues. 1993 Jun 3
34 8375018 Cellular approaches to bioreductive drug mechanisms. 1993 Jun 1
35 1651729 High levels of expression of the NAD(P)H:quinone oxidoreductase (NQO1) gene in tumor cells compared to normal cells of the same origin. 1991 Aug 8 1
36 2557982 On the mechanism of the Mn3(+)-induced neurotoxicity of dopamine:prevention of quinone-derived oxygen toxicity by DT diaphorase and superoxide dismutase. 1989 1
37 2855420 Effect of superoxide dismutase on the autoxidation of various hydroquinones--a possible role of superoxide dismutase as a superoxide:semiquinone oxidoreductase. 1988 1
38 28474 Inhibition of azoreductase by oxygen. The role of the azo anion free radical metabolite in the reduction of oxygen to superoxide. 1978 Jul 1