10 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 16129418 | Crystal structure of quinone reductase 2 in complex with cancer prodrug CB1954. | 2005 Oct 14 | 1 |
2 | 14529407 | CB 1954: from the Walker tumor to NQO2 and VDEPT. | 2003 | 1 |
3 | 11361019 | Demonstration of the activation of prodrug CB 1954 using human DT-diaphorase mutant Q104Y-transfected MDA-MB-231 cells and mouse xenograft model. | 2001 Jan 1 | 1 |
4 | 10419545 | Molecular characterization of binding of substrates and inhibitors to DT-diaphorase: combined approach involving site-directed mutagenesis, inhibitor-binding analysis, and computer modeling. | 1999 Aug | 1 |
5 | 10543876 | Crystal structure of human DT-diaphorase: a model for interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954). | 1999 Oct 21 | 2 |
6 | 10656629 | Role of redox cycling and activation by DT-diaphorase in the cytotoxicity of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB-1954) and its analogs. | 1999 Nov 15 | 7 |
7 | 9367528 | Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase. | 1997 Nov 15 | 1 |
8 | 8375021 | The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT). | 1993 Jun | 1 |
9 | 1449531 | Potentiation of CB 1954 cytotoxicity by reduced pyridine nucleotides in human tumour cells by stimulation of DT diaphorase activity. | 1992 Nov 3 | 2 |
10 | 1901207 | The differences in kinetics of rat and human DT diaphorase result in a differential sensitivity of derived cell lines to CB 1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide) | 1991 Mar 15-Apr 1 | 7 |