Pub. Date : 2010 Jun
PMID : 19636701
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Co-amplification of CCND1 and EMSY is associated with an adverse outcome in ER-positive tamoxifen-treated breast cancers. | Tamoxifen | cyclin D1 | Homo sapiens |
| 2 | Both CCND1 and EMSY amplifications were associated with a significantly worse outcome in ER-positive patients treated with tamoxifen only, in contrast to nonamplified tumors (P = 8.55 x 10(-4) and P = 8.35 x 10(-5), respectively). | Tamoxifen | cyclin D1 | Homo sapiens |
| 3 | In summary, co-amplification of CCND1 and EMSY identified a poor prognostic subset of ER-positive tamoxifen-treated patients. | Tamoxifen | cyclin D1 | Homo sapiens |