Doxorubicin

phosphoglycolate phosphatase ; Mus musculus







76 Article(s)
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1 34748960 All-in-one nanosponge with pluronic shell for synergistic anticancer therapy through effectively overcoming multidrug resistance in cancer. 2022 Feb 3
2 35477542 Chemosensitizing effect and mechanism of imperatorin on the anti-tumor activity of doxorubicin in tumor cells and transplantation tumor model. 2022 May 1 1
3 35584053 Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance. 2022 Jun 13 4
4 33341670 Overcoming multidrug resistance by intracellular drug release and inhibiting p-glycoprotein efflux in breast cancer. 2021 Feb 1
5 34554637 Activatable Biomineralized Nanoplatform Remodels the Intracellular Environment of Multidrug-Resistant Tumors for Enhanced Ferroptosis/Apoptosis Therapy. 2021 Nov 1
6 31954717 The effects of anthracycline drugs on the conformational distribution of mouse P-glycoprotein explains their transport rate differences. 2020 Apr 6
7 32061772 Canagliflozin inhibits p-gp function and early autophagy and improves the sensitivity to the antitumor effect of doxorubicin. 2020 May 1
8 32313056 Improving Treatment Efficacy of In Situ Forming Implants via Concurrent Delivery of Chemotherapeutic and Chemosensitizer. 2020 Apr 20 3
9 32395707 Aptamer-functionalized Hybrid Nanoparticles to Enhance the Delivery of Doxorubicin into Breast Cancer Cells by Silencing P-glycoprotein. 2020 12
10 32572883 The tissue transglutaminase: a potential target regulating MDR in breast cancer. 2020 Jun 1
11 32747282 Dextran methacrylate hydrogel microneedles loaded with doxorubicin and trametinib for continuous transdermal administration of melanoma. 2020 Oct 15 2
12 29985077 Dioscorea bulbifera L. delays the excretion of doxorubicin and aggravates doxorubicin-induced cardiotoxicity and nephrotoxicity by inhibiting the expression of P-glycoprotein in mice liver and kidney. 2019 Sep 2
13 30677228 Programmable Codelivery of Doxorubicin and Apatinib Using an Implantable Hierarchical-Structured Fiber Device for Overcoming Cancer Multidrug Resistance. 2019 Feb 1
14 31441308 Induction of Mitochondrial Cell Death and Reversal of Anticancer Drug Resistance via Nanocarriers Composed of a Triphenylphosphonium Derivative of Tocopheryl Polyethylene Glycol Succinate. 2019 Sep 3 2
15 28681913 Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca2+ -mediated apoptosis pathways in MCF-7/ADR and K562/ADR. 2018 Apr 2
16 29191785 Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors. 2018 Jan 28 1
17 29414892 Effects of Phytochemical P-Glycoprotein Modulators on the Pharmacokinetics and Tissue Distribution of Doxorubicin in Mice. 2018 Feb 7 4
18 30288040 Doxorubicin-loaded dextran-based nano-carriers for highly efficient inhibition of lymphoma cell growth and synchronous reduction of cardiac toxicity. 2018 1
19 30482226 Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer. 2018 Nov 27 2
20 27760838 Identification and Validation of Compounds Selectively Killing Resistant Cancer: Delineating Cell Line-Specific Effects from P-Glycoprotein-Induced Toxicity. 2017 Jan 2
21 27777271 Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance. 2017 Jan 2
22 27459414 Disulphide cross linked pullulan based cationic polymer for improved gene delivery and efflux pump inhibition. 2016 Oct 1 1
23 25661387 Soluplus(®) micelles as a potential drug delivery system for reversal of resistant tumor. 2015 Feb 3
24 25770771 Doxorubicin and curcumin co-delivery by lipid nanoparticles for enhanced treatment of diethylnitrosamine-induced hepatocellular carcinoma in mice. 2015 Jun 1
25 26598918 Medicarpin and millepurpan, two flavonoids isolated from Medicago sativa, induce apoptosis and overcome multidrug resistance in leukemia P388 cells. 2015 Dec 1 2
26 24396453 Enhanced activity of doxorubicin in drug resistant A549 tumor cells by encapsulation of P-glycoprotein inhibitor in PLGA-based nanovectors. 2014 Feb 3
27 24780744 In vivo anticancer synergy mechanism of doxorubicin and verapamil combination treatment is impaired in BALB/c mice with metastatic breast cancer. 2014 Aug 5
28 25238617 The strong in vivo anti-tumor effect of the UIC2 monoclonal antibody is the combined result of Pgp inhibition and antibody dependent cell-mediated cytotoxicity. 2014 2
29 25587220 Induction of multiple drug resistance in HMEC-1 endothelial cells after long-term exposure to sunitinib. 2014 6
30 23793993 Bioactive lipids-based pH sensitive micelles for co-delivery of doxorubicin and ceramide to overcome multidrug resistance in leukemia. 2013 Nov 1
31 23837843 Induction of acquired drug resistance in endothelial cells and its involvement in anticancer therapy. 2013 Jul 9 3
32 21983837 A comparative small-animal PET evaluation of [11C]tariquidar, [11C]elacridar and (R)-[11C]verapamil for detection of P-glycoprotein-expressing murine breast cancer. 2012 Jan 1
33 22615365 Heat shock factor-1 knockout induces multidrug resistance gene, MDR1b, and enhances P-glycoprotein (ABCB1)-based drug extrusion in the heart. 2012 Jun 5 4
34 21590773 Acute exposure to doxorubicin results in increased cardiac P-glycoprotein expression. 2011 Sep 6
35 21638135 siRNA-mediated down-regulation of P-glycoprotein in a Xenograft tumor model in NOD-SCID mice. 2011 Oct 1
36 20137116 [Effects of compound Zhe-Bei granule (CZBG) combined with doxorubicin on expression of membrane transport proteins in K562/A02 cell xenografts]. 2010 Feb 2
37 20514403 Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer. 2010 Jul 6
38 20600887 Sequential treatment of drug-resistant tumors with RGD-modified liposomes containing siRNA or doxorubicin. 2010 Oct 2
39 19093112 Noninvasive functional imaging of P-glycoprotein-mediated doxorubicin resistance in a mouse model of hereditary breast cancer to predict response, and assign P-gp inhibitor sensitivity. 2009 Mar 1
40 19654309 Moderate increase in Mdr1a/1b expression causes in vivo resistance to doxorubicin in a mouse model for hereditary breast cancer. 2009 Aug 15 3
41 19807929 The influence of P-glycoprotein expression and its inhibitors on the distribution of doxorubicin in breast tumors. 2009 Oct 6 8
42 20055093 Development of idarubicin and doxorubicin solid lipid nanoparticles to overcome Pgp-mediated multiple drug resistance in leukemia. 2009 Apr 2
43 17477907 Induction of autoantibodies to murine P-glycoprotein: consequences on drug sensitivity in MDR cancer cells and on the expression of mdr genes in organs. 2007 Jun 22 1
44 17517470 Immunization with liposome-anchored pegylated peptides modulates doxorubicin sensitivity in P-glycoprotein-expressing P388 cells. 2007 Nov 18 3
45 16465381 Selection of non-P-glycoprotein mediated high-level etoposide resistant cell lines by adriamycin with P-gp inhibitors. 2006 Mar 1
46 16707254 Suppression of P-glycoprotein expression by antipsychotics trifluoperazine in adriamycin-resistant L1210 mouse leukemia cells. 2006 Jul 1
47 16962737 L1210 cells cultivated under the selection pressure of doxorubicin or vincristine express common mechanisms of multidrug resistance based on the overexpression of P-glycoprotein. 2006 Dec 2
48 15763623 Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor. 2005 Mar 21 1
49 15778272 Impact of endotoxin-induced changes in P-glycoprotein expression on disposition of doxorubicin in mice. 2005 Jun 4
50 15835751 Isolated rafts from adriamycin-resistant P388 cells contain functional ATPases and provide an easy test system for P-glycoprotein-related activities. 2005 Mar 1