| 1 |
29016820 | Selective BCL-XL inhibition promotes apoptosis in combination with MLN8237 in medulloblastoma and pediatric glioblastoma cells. | 2018 Jan 22 |
1 |
| 2 |
29459767 | Mcl-1 and Bcl-xL sequestration of Bak confers differential resistance to BH3-only proteins. | 2018 Mar |
1 |
| 3 |
27935869 | The involvement of Bcl-2 family proteins in AKT-regulated cell survival in cisplatin resistant epithelial ovarian cancer. | 2017 Jan 3 |
2 |
| 4 |
27172402 | BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mimetic activity and has only minimal effects on autophagic flux. | 2016 Jul 2 |
1 |
| 5 |
27460078 | VHL-deficient renal cancer cells gain resistance to mitochondria-activating apoptosis inducers by activating AKT through the IGF1R-PI3K pathway. | 2016 Oct |
5 |
| 6 |
25548100 | Reversal of Mutant KRAS-Mediated Apoptosis Resistance by Concurrent Noxa/Bik Induction and Bcl-2/Bcl-xL Antagonism in Colon Cancer Cells. | 2015 Apr |
1 |
| 7 |
25916945 | Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells. | 2015 Jul |
1 |
| 8 |
24402163 | Both leukaemic and normal peripheral B lymphoid cells are highly sensitive to the selective pharmacological inhibition of prosurvival Bcl-2 with ABT-199. | 2014 Jun |
1 |
| 9 |
24614082 | Rapamycin rescues ABT-737 efficacy in small cell lung cancer. | 2014 May 15 |
2 |
| 10 |
25304383 | Clitocine induces apoptosis and enhances the lethality of ABT-737 in human colon cancer cells by disrupting the interaction of Mcl-1 and Bak. | 2014 Dec 28 |
2 |
| 11 |
23480852 | BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins. | 2013 May 15 |
2 |
| 12 |
23557083 | Pan-BH3 mimetic S1 exhibits broad-spectrum antitumour effects by cooperation between Bax and Bak. | 2013 Sep |
1 |
| 13 |
23680104 | The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak. | 2013 May 16 |
1 |
| 14 |
23832116 | Evaluation and critical assessment of putative MCL-1 inhibitors. | 2013 Nov |
1 |
| 15 |
24058878 | ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells. | 2013 |
3 |
| 16 |
24120870 | BIM-mediated membrane insertion of the BAK pore domain is an essential requirement for apoptosis. | 2013 Oct 31 |
1 |
| 17 |
22052464 | Finding a Panacea among combination cancer therapies. | 2012 Jan 1 |
2 |
| 18 |
22764103 | Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737. | 2012 Jul 5 |
1 |
| 19 |
21949692 | Efficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapy. | 2011 |
3 |
| 20 |
20493813 | Resistance to caspase-independent cell death requires persistence of intact mitochondria. | 2010 May 18 |
1 |
| 21 |
17943175 | Synergistic antileukemic effects between ABT-869 and chemotherapy involve downregulation of cell cycle-regulated genes and c-Mos-mediated MAPK pathway. | 2008 Jan |
1 |
| 22 |
18413764 | BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells. | 2008 Apr 15 |
2 |
| 23 |
19088028 | Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737. | 2008 Dec 15 |
1 |
| 24 |
17234790 | Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation. | 2007 Jan 15 |
6 |
| 25 |
17409392 | Targeting multiple arms of the apoptotic regulatory machinery. | 2007 Apr 1 |
2 |