Title : Synergistic antileukemic effects between ABT-869 and chemotherapy involve downregulation of cell cycle-regulated genes and c-Mos-mediated MAPK pathway.

Pub. Date : 2008 Jan

PMID : 17943175






1 Functional Relationships(s)
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1 ABT-869 induces apoptosis through downregulation of Bcl-xL and upregulation of BAK, BID and BAD. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid BCL2 antagonist/killer 1 Homo sapiens