epoxyeicosatrienoic acids

cytochrome P450 family 2 subfamily J member 2 ; Homo sapiens







43 Article(s)
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1 34044117 Atypical kinetics of cytochrome P450 2J2: Epoxidation of arachidonic acid and reversible inhibition by xenobiotic inhibitors. 2021 Sep 1 1
2 34405218 [Endogenous protective effects of arachidonic acid epoxygenase metabolites, epoxyeicosatrienoic acids, in cardiovascular system]. 2021 Aug 25 1
3 34707002 CYP2J2-produced epoxyeicosatrienoic acids contribute to the ferroptosis resistance of pancreatic ductal adenocarcinoma in a PPARγ-dependent manner. 2021 Sept 28 3
4 31902555 Association of CYP2J2 polymorphism with susceptibility to psoriasis in Turkish population: a case-control study. 2020 Jan - Feb 1
5 32210298 CYP2J2 Modulates Diverse Transcriptional Programs in Adult Human Cardiomyocytes. 2020 Mar 24 1
6 32224017 Influence of the CYP2J2 Gene Polymorphisms on Chronic Obstructive Pulmonary Disease Risk in the Chinese Han Population. 2020 Nov 1
7 33239900 The Human Genetic Variants CYP2J2 rs2280275 and EPHX2 rs751141 and Risk of Diabetic Nephropathy in Egyptian Type 2 Diabetic Patients. 2020 1
8 30518987 A comprehensive study revealed SNP-SNP interactions and a sex-dependent relationship between polymorphisms of the CYP2J2 gene and hypertension risk. 2019 Feb 2
9 29433675 Plant natural product plumbagin presents potent inhibitory effect on human cytochrome P450 2J2 enzyme. 2018 Jan 15 1
10 29580941 Increased epoxyeicosatrienoic acids may be part of a protective mechanism in human ulcerative colitis, with increased CYP2J2 and reduced soluble epoxide hydrolase expression. 2018 May 1
11 29695613 Cytochrome P450 2J2: Potential Role in Drug Metabolism and Cardiotoxicity. 2018 Aug 2
12 29715548 Posttranslational regulation of CYP2J2 by nitric oxide. 2018 Jun 1
13 28237650 Inhibition and inactivation of human CYP2J2: Implications in cardiac pathophysiology and opportunities in cancer therapy. 2017 Jul 1 1
14 28374982 Angiotensin II Receptor Blockers Inhibit the Generation of Epoxyeicosatrienoic Acid from Arachidonic Acid in Recombinant CYP2C9, CYP2J2 and Human Liver Microsomes. 2017 Oct 1
15 28958841 Effects of dronedarone, amiodarone and their active metabolites on sequential metabolism of arachidonic acid to epoxyeicosatrienoic and dihydroxyeicosatrienoic acids. 2017 Dec 15 2
16 25560582 Association of CYP2C8, CYP2C9 and CYP2J2 gene polymorphisms with myocardial infarction in South Indian population. 2015 Feb 1
17 25870948 CYP2J2 and EETs protect against lung ischemia/reperfusion injury via anti-inflammatory effects in vivo and in vitro. 2015 2
18 24788058 Potential of decursin to inhibit the human cytochrome P450 2J2 isoform. 2014 Aug 2
19 24882266 Human cytochrome P450 epoxygenases: variability in expression and role in inflammation-related disorders. 2014 Nov 1
20 25277139 Endocannabinoids anandamide and 2-arachidonoylglycerol are substrates for human CYP2J2 epoxygenase. 2014 Dec 1
21 23474289 Roles of the epoxygenase CYP2J2 in the endothelium. 2013 Dec 1
22 23647230 Structural basis for the mutation-induced dysfunction of human CYP2J2: a computational study. 2013 Jun 24 1
23 23684773 A novel polymorphism of the CYP2J2 gene is associated with coronary artery disease in Uygur population in China. 2013 Aug 1
24 23688134 Extra-hepatic isozymes from the CYP1 and CYP2 families as potential chemotherapeutic targets. 2013 1
25 21030485 Cytochrome P450 2J2 is highly expressed in hematologic malignant diseases and promotes tumor cell growth. 2011 Feb 2
26 21642892 Association between polymorphisms of CYP2J2 and EPHX2 genes and risk of coronary artery disease. 2011 Aug 2
27 20093140 Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases. 2010 Mar 1
28 19289568 Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo. 2009 Jun 1
29 19944311 Eicosapentaenoic acid increases cytochrome P-450 2J2 gene expression and epoxyeicosatrienoic acid production via peroxisome proliferator-activated receptor γ in endothelial cells. 2009 Dec 1
30 18216721 Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population. 2008 Jan 2
31 18496133 Common variation in cytochrome P450 epoxygenase genes and the risk of incident nonfatal myocardial infarction and ischemic stroke. 2008 Jun 1
32 18769365 Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease. 2008 Nov 1
33 17126841 Synergistic effect of cytochrome P450 epoxygenase CYP2J2*7 polymorphism with smoking on the onset of premature myocardial infarction. 2007 Nov 1
34 17220242 Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues. 2007 Apr 1
35 17429317 CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk: the Atherosclerosis Risk in Communities (ARIC) study. 2007 May 1
36 17652182 Electrophysiological properties of cardiomyocytes isolated from CYP2J2 transgenic mice. 2007 Oct 1
37 16868033 Variability of CYP2J2 expression in human fetal tissues. 2006 Nov 1
38 16008525 Characterization of a c-Jun-responsive module in the 5'-flank of the human CYP2J2 gene that regulates transactivation. 2005 Nov 1 2
39 15466638 Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2. 2004 Oct 12 1
40 11455018 Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. 2001 Aug 1
41 8631948 Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart. 1996 Feb 16 2
42 2563927 Effect of epoxyeicosatrienoic acids on growth hormone release from somatotrophs. 1989 Feb 1
43 3580381 Arachidonic acid epoxygenase: detection of epoxyeicosatrienoic acids in human urine. 1987 Jun 2 1