Title : Structural basis for the mutation-induced dysfunction of human CYP2J2: a computational study.

Pub. Date : 2013 Jun 24

PMID : 23647230






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In cardiac tissues, CYP2J2 can adopt arachidonic acid as a major substrate to produce epoxyeicosatrienoic acids (EETs), which can protect endothelial cells from ischemic or hypoxic injuries and have been implicated in the pathogenesis of coronary artery disease and hypertension. epoxyeicosatrienoic acids cytochrome P450 family 2 subfamily J member 2 Homo sapiens