Nitrogen

N-acetyltransferase 2 ; Homo sapiens







28 Article(s)
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1 29180287 Role of N-acetyltransferase 2 acetylation polymorphism in 4, 4'-methylene bis (2-chloroaniline) biotransformation. 2018 Feb 1
2 30149019 Expression and genotype-dependent catalytic activity of N-acetyltransferase 2 (NAT2) in human peripheral blood mononuclear cells and its modulation by Sirtuin 1. 2018 Oct 1
3 28516247 Genetic heterogeneity among slow acetylator N-acetyltransferase 2 phenotypes in cryopreserved human hepatocytes. 2017 Jul 4
4 28752039 Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved human hepatocytes. 2017 Jul 1
5 29018032 N-Acetyltransferase 2 Genotype-Dependent N-Acetylation of Hydralazine in Human Hepatocytes. 2017 Dec 1
6 27223070 Differential association for N-acetyltransferase 2 genotype and phenotype with bladder cancer risk in Chinese population. 2016 Jun 28 3
7 26715854 Risks on N-acetyltransferase 2 and bladder cancer: a meta-analysis. 2015 1
8 24309420 Dimethocaine, a synthetic cocaine derivative: studies on its in vitro metabolism catalyzed by P450s and NAT2. 2014 Feb 10 1
9 25241292 Gender and functional CYP2C and NAT2 polymorphisms determine the metabolic profile of metamizole. 2014 Dec 1 1
10 19666988 Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline. 2009 Nov 2
11 17479278 Re-assessment of the influence of polymorphisms of phase-II metabolic enzymes on renal cell cancer risk of trichloroethylene-exposed workers. 2007 Nov 1
12 17672512 Arylamine N-acetyltransferases: characterization of the substrate specificities and molecular interactions of environmental arylamines with human NAT1 and NAT2. 2007 Sep 1
13 12016157 Excretion of the N(2)-glucuronide conjugate of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in urine and its relationship to CYP1A2 and NAT2 activity levels in humans. 2002 May 1
14 12222688 Functional genomics of C190T single nucleotide polymorphism in human N-acetyltransferase 2. 2002 Jun 3
15 12351146 Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis. 2002 Sep 30 2
16 11337936 Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms. 2001 Apr 1
17 11604271 Kinetic phenotypic diagnosis of N-acetylation polymorphism in patients based on ratio of urinary metabolites of salicylazosulfapyridine. 2001 Oct 23 1
18 10537291 N-oxidative metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in humans: excretion of the N2-glucuronide conjugate of 2-hydroxyamino-MeIQx in urine. 1999 Oct 15 1
19 9459121 Epidermal N-acetylation of p-aminobenzoyl glutamic acid: difference in response to ultraviolet B irradiation. 1998 Jan 1
20 9572394 Characterization of a hormone response element in the mouse N-acetyltransferase 2 (Nat2*) promoter. 1998 1
21 9202744 Rodent models of the human acetylation polymorphism: comparisons of recombinant acetyltransferases. 1997 May 12 1
22 8643532 The impact of interindividual variation in NAT2 activity on benzidine urinary metabolites and urothelial DNA adducts in exposed workers. 1996 May 14 1
23 7627960 Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of 7 specific NAT2 nucleic acid substitutions. 1995 Aug 15 1
24 8844812 Metabolic activation and DNA adduct detection of PhIP in dogs, rats, and humans in relation to urinary bladder and colon carcinogenesis. 1995 1
25 8081359 Molecular genetics of human polymorphic N-acetyltransferase: enzymatic analysis of 15 recombinant wild-type, mutant, and chimeric NAT2 allozymes. 1994 May 1
26 8225481 32P-postlabelling studies on the DNA adducts of the food mutagens/carcinogens IQ and PhIP--adduct formation in a chemical system, and by rat and human metabolism. 1993 1
27 8353847 Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. 1993 Aug 1
28 1423830 The role of the human acetylation polymorphism in the metabolic activation of the food carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ). 1992 Oct 1