Doxorubicin

major vault protein ; Homo sapiens







30 Article(s)
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1 34871862 miR-197-5p increases Doxorubicin-mediated anticancer cytotoxicity of HT1080 fibrosarcoma cells by decreasing drug efflux. 2022 Jan 1
2 30336197 Major vault protein is a direct target of Notch1 signaling and contributes to chemoresistance in triple-negative breast cancer cells. 2019 Jan 1
3 30654824 Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault proteinĀ (MVP). 2019 Jan 17 1
4 29085470 Reversal of doxorubicin-resistance by Salvia miltiorrhiza ligustrazine in the SHG44/doxorubicin glioma drug-resistant cell line. 2017 Oct 2
5 29333049 Marine-derived Fungi Extracts Enhance the Cytotoxic Activity of Doxorubicin in Nonsmall Cell Lung Cancer Cells A459. 2017 Dec 2
6 27817195 Mechanisms underlying lung resistance-related protein (LRP)-mediated doxorubicin resistance of non-small cell lung cancer cells. 2016 Dec 31 7
7 24997994 Proteomic analysis reveals a role for Bcl2-associated athanogene 3 and major vault protein in resistance to apoptosis in senescent cells by regulating ERK1/2 activation. 2015 Jan 2
8 25603048 ABCB1, ABCC1, and LRP gene expressions are altered by LDL, HDL, and serum deprivation in a human doxorubicin-resistant uterine sarcoma cell line. 2015 Feb 20 2
9 24253450 Binding and inhibition of drug transport proteins by heparin: a potential drug transporter modulator capable of reducing multidrug resistance in human cancer cells. 2014 Jan 2
10 22940126 Overcoming drug resistance of MCF-7/ADR cells by altering intracellular distribution of doxorubicin via MVP knockdown with a novel siRNA polyamidoamine-hyaluronic acid complex. 2012 Oct 28 8
11 21344396 p53 Suppresses lung resistance-related protein expression through Y-box binding protein 1 in the MCF-7 breast tumor cell line. 2011 Dec 1
12 17031644 Differential effects of the immunosuppressive agents cyclosporin A, tacrolimus and sirolimus on drug transport by multidrug resistance proteins. 2007 Jul 1
13 17134750 Multidrug resistance protein expression of adult T-cell leukemia/lymphoma. 2007 Apr 2
14 17575109 Depletion of major vault protein increases doxorubicin sensitivity and nuclear accumulation and disrupts its sequestration in lysosomes. 2007 Jun 3
15 16465425 Direct activation of the human major vault protein gene by DNA-damaging agents. 2006 Mar 1
16 16953094 Molecular cloning of feline lung resistance-related protein (LRP) cDNA and its expression in a feline lymphoma cell line and adriamycin-resistant subline. 2006 Aug 2
17 15788683 Cyclosporin A is a broad-spectrum multidrug resistance modulator. 2005 Mar 15 1
18 12488537 Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors. 2003 Jan 1
19 12576456 RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: correlation with chemotherapeutic response. 2003 Feb 1
20 11774257 A very early induction of major vault protein accompanied by increased drug resistance in U-937 cells. 2002 Jan 10 2
21 12110277 Role of the lung resistance-related protein (LRP) in the drug sensitivity of cultured tumor cells. 2002 Aug 1
22 11149411 Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells. 2001 Jan 1 1
23 11290872 Sequential gene expression of P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP) and lung resistance protein: functional activity of P-gp and MRP present in the doxorubicin-resistant human K562 cell lines. 2001 Mar 1
24 11493465 Expression of functional lung resistance--related protein predicts poor outcome in adult T-cell leukemia. 2001 Aug 15 4
25 10764626 Low-level doxorubicin resistance in benzo[a]pyrene-treated KB-3-1 cells is associated with increased LRP expression and altered subcellular drug distribution. 2000 Apr 15 2
26 11004683 Expression of the major vault protein LRP in human non-small-cell lung cancer cells: activation by short-term exposure to antineoplastic drugs. 2000 Oct 15 2
27 10511592 Multidrug resistance and the lung resistance-related protein in human colon carcinoma SW-620 cells. 1999 Oct 6 5
28 9436635 Expression of lung resistance-related protein (LRP) in non-small cell lung carcinomas of smokers and non-smokers and its predictive value for doxorubicin resistance. 1997 Nov 1
29 8605092 Low-level doxorubicin resistance in P-glycoprotein-negative human pancreatic tumour PSN1/ADR cells implicates a brefeldin A-sensitive mechanism of drug extrusion. 1996 Mar 2
30 7671223 The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification. 1995 Oct 1 2