Pub. Date : 2017 Oct
PMID : 29085470
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The SHG44/DOX cells grew continually in 0.1 microg/ml DOX and expressed increased levels of mRNA of multidrug resistance genes [multidrug resistance 1 (MDR1), multidrug resistance-associated protein 1 (MRP1) and lung resistance protein (LRP)] compared with the parental SHG44 cells. | Doxorubicin | major vault protein | Homo sapiens |
2 | In addition, the levels of MDR1, MRP1 and LRP were downregulated by this traditional Chinese medicine, coupled with increased intracellular DOX concentrations. | Doxorubicin | major vault protein | Homo sapiens |