Gangliosides

synuclein alpha ; Homo sapiens







14 Article(s)
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1 34328594 Innovative treatment targeting gangliosides aimed at blocking the formation of neurotoxic α-synuclein oligomers in Parkinson's disease. 2022 Feb 4
2 34768981 Gene Therapy Strategy for Alzheimer's and Parkinson's Diseases Aimed at Preventing the Formation of Neurotoxic Oligomers in SH-SY5Y Cells. 2021 Oct 26 2
3 30878495 Reprint of "Ganglioside lipids accelerate α-synuclein amyloid formation". 2019 May 1
4 31698188 GM1 Ganglioside role in the interaction of Alpha-synuclein with lipid membranes: Morphology and structure. 2019 Dec 3
5 29632069 Extracellular α-synuclein drives sphingosine 1-phosphate receptor subtype 1 out of lipid rafts, leading to impaired inhibitory G-protein signaling. 2018 May 25 1
6 30077783 Ganglioside lipids accelerate α-synuclein amyloid formation. 2018 Aug 2 1
7 27261254 Gangliosides of the Vertebrate Nervous System. 2016 Aug 14 1
8 27352802 Common molecular mechanism of amyloid pore formation by Alzheimer's β-amyloid peptide and α-synuclein. 2016 Jun 29 1
9 24903509 Pathogenic role of ganglioside metabolism in neurodegenerative diseases. 2014 Oct 1
10 25140899 Deciphering the glycolipid code of Alzheimer's and Parkinson's amyloid proteins allowed the creation of a universal ganglioside-binding peptide. 2014 2
11 23775688 The driving force of alpha-synuclein insertion and amyloid channel formation in the plasma membrane of neural cells: key role of ganglioside- and cholesterol-binding domains. 2013 2
12 21396938 Molecular basis for the glycosphingolipid-binding specificity of α-synuclein: key role of tyrosine 39 in membrane insertion. 2011 May 13 1
13 20114052 Altered ion channel formation by the Parkinson's-disease-linked E46K mutant of alpha-synuclein is corrected by GM3 but not by GM1 gangliosides. 2010 Mar 19 2
14 17253773 GM1 specifically interacts with alpha-synuclein and inhibits fibrillation. 2007 Feb 20 3