| 1 |
35054318 | Recognized and Emerging Features of Erythropoietic and X-Linked Protoporphyria. | 2022 Jan 8 |
1 |
| 2 |
35309058 | Microcytosis in Erythropoietic Protoporphyria. | 2022 |
2 |
| 3 |
33475175 | Erythropoietic protoporphyria- associated hepatopathy: expanding the spectra of brown pigments encountered in hepatic specimens. | 2021 Jul |
1 |
| 4 |
34582890 | Ironing out the distribution of [2Fe-2S] motifs in ferrochelatases. | 2021 Nov |
1 |
| 5 |
34940556 | Iron, Heme Synthesis and Erythropoietic Porphyrias: A Complex Interplay. | 2021 Nov 23 |
7 |
| 6 |
30517741 | The Isoniazid Metabolites Hydrazine and Pyridoxal Isonicotinoyl Hydrazone Modulate Heme Biosynthesis. | 2019 Mar 1 |
1 |
| 7 |
30767226 | Ferrochelatase Deficiency Abrogated the Enhancement of Aminolevulinic Acid-mediated Protoporphyrin IX by Iron Chelator Deferoxamine. | 2019 Jul |
4 |
| 8 |
31076252 | Delta-aminolevulinic acid synthase 2 expression in combination with iron as modifiers of disease severity in erythropoietic protoporphyria. | 2019 Nov |
1 |
| 9 |
28185024 | Disturbed iron metabolism in erythropoietic protoporphyria and association of GDF15 and gender with disease severity. | 2017 May |
1 |
| 10 |
29247132 | The heme synthesis defect of mutants impaired in mitochondrial iron-sulfur protein biogenesis is caused by reversible inhibition of ferrochelatase. | 2017 Dec 15 |
1 |
| 11 |
26100117 | Functional Analysis of GLRX5 Mutants Reveals Distinct Functionalities of GLRX5 Protein. | 2016 Jan |
1 |
| 12 |
27627839 | Erythroid cell mitochondria receive endosomal iron by a "kiss-and-run" mechanism. | 2016 Dec |
3 |
| 13 |
27801584 | Human Ferrochelatase: Insights for the Mechanism of Ferrous Iron Approaching Protoporphyrin IX by QM/MM and QTCP Free Energy Studies. | 2016 Dec 27 |
2 |
| 14 |
25179834 | In ferrochelatase-deficient protoporphyria patients, ALAS2 expression is enhanced and erythrocytic protoporphyrin concentration correlates with iron availability. | 2015 Jan |
2 |
| 15 |
25826316 | Molecular insights into frataxin-mediated iron supply for heme biosynthesis in Bacillus subtilis. | 2015 |
2 |
| 16 |
24864106 | [Heme metabolism as an integral part of iron homeostasis]. | 2014 Jan 2 |
1 |
| 17 |
22862424 | The p53-dependent expression of frataxin controls 5-aminolevulinic acid-induced accumulation of protoporphyrin IX and photo-damage in cancerous cells. | 2013 Jan-Feb |
1 |
| 18 |
23787363 | Iron availability modulates aberrant splicing of ferrochelatase through the iron- and 2-oxoglutarate dependent dioxygenase Jmjd6 and U2AF(65.). | 2013 Oct |
3 |
| 19 |
22712763 | Identification and characterization of solvent-filled channels in human ferrochelatase. | 2012 Jul 10 |
1 |
| 20 |
22897320 | Dissection of porphyrin-induced conformational dynamics in the heme biosynthesis enzyme ferrochelatase. | 2012 Sep 11 |
4 |
| 21 |
21627978 | Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria. | 2011 Jul |
2 |
| 22 |
21776189 | Resonance Raman Spectroscopic Examination of Ferrochelatase-induced Porphyrin Distortion. | 2011 May |
1 |
| 23 |
21852895 | FERROCHELATASE: THE CONVERGENCE OF THE PORPHYRIN BIOSYNTHESIS AND IRON TRANSPORT PATHWAYS. | 2011 |
4 |
| 24 |
22020364 | Modulating ALA-PDT efficacy of mutlidrug resistant MCF-7 breast cancer cells using ALA prodrug. | 2011 Dec |
1 |
| 25 |
19965627 | Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery. | 2010 Jan 28 |
8 |
| 26 |
20427704 | Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis. | 2010 Jul 29 |
2 |
| 27 |
20622448 | Porcine ferrochelatase: the relationship between iron-removal reaction and the conversion of heme to Zn-protoporphyrin. | 2010 |
2 |
| 28 |
19703464 | Product release rather than chelation determines metal specificity for ferrochelatase. | 2009 Oct 23 |
1 |
| 29 |
19767646 | Metal ion selectivity and substrate inhibition in the metal ion chelation catalyzed by human ferrochelatase. | 2009 Dec 4 |
2 |
| 30 |
19955842 | Regulation of 5-aminolevulinic acid-mediated protoporphyrin IX accumulation in human urothelial carcinomas. | 2009 |
1 |
| 31 |
16870250 | Candidate gene mutation analysis in idiopathic acquired sideroblastic anemia (refractory anemia with ringed sideroblasts). | 2007 May |
1 |
| 32 |
17261801 | Substrate interactions with human ferrochelatase. | 2007 Feb 6 |
1 |
| 33 |
17499976 | Hemin rescues adrenodoxin, heme a and cytochrome oxidase activity in frataxin-deficient oligodendroglioma cells. | 2007 Jul |
1 |
| 34 |
17566985 | Direct measurement of metal ion chelation in the active site of human ferrochelatase. | 2007 Jul 10 |
2 |
| 35 |
17567154 | Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis. | 2007 Jul 10 |
1 |
| 36 |
17711525 | Late presentation of erythropoietic protoporphyria: case report and genetic analysis of family members. | 2007 Nov |
2 |
| 37 |
17884090 | A pi-helix switch selective for porphyrin deprotonation and product release in human ferrochelatase. | 2007 Nov 2 |
1 |
| 38 |
18044970 | Heme synthase (ferrochelatase) catalyzes the removal of iron from heme and demetalation of metalloporphyrins. | 2007 Dec 25 |
4 |
| 39 |
16469498 | Chelatases: distort to select? | 2006 Mar |
4 |
| 40 |
16614385 | The influence of sex steroid hormones on ferrochelatase gene expression in Harderian gland of hamster (Mesocricetus auratus). | 2006 Apr |
1 |
| 41 |
16839620 | Biosynthesis of heme in mammals. | 2006 Jul |
2 |
| 42 |
17017521 | Iron and Friedreich ataxia. | 2006 |
1 |
| 43 |
15123683 | Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis. | 2004 Jun 18 |
8 |
| 44 |
15312748 | Regulation of ferrochelatase gene expression by hypoxia. | 2004 Sep 10 |
2 |
| 45 |
15532727 | Cloning and characterization of chironomidae ferrochelatase: copper activation of the purified ferrochelatase. | 2004 Jul |
2 |
| 46 |
12782026 | A continuous anaerobic fluorimetric assay for ferrochelatase by monitoring porphyrin disappearance. | 2003 Jul 1 |
1 |
| 47 |
12196181 | Iron targeting to mitochondria in erythroid cells. | 2002 Aug |
3 |
| 48 |
12417755 | Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging. | 2002 Nov 12 |
2 |
| 49 |
11451377 | Purification and properties of ferrochelatase from Chironomidae larvae. | 2001 Apr |
1 |
| 50 |
11502175 | Human ferrochelatase: characterization of substrate-iron binding and proton-abstracting residues. | 2001 Aug 21 |
3 |