Title : Functional Analysis of GLRX5 Mutants Reveals Distinct Functionalities of GLRX5 Protein.

Pub. Date : 2016 Jan

PMID : 26100117






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We observed that the K101Q mutation (due to c. 301 A>C mutation) may prevent the binding of [Fe-S] to GLRX5 protein, while L148S (due to c. 443 T>C mutation) may interfere with [Fe-S] transfer from GLRX5 to iron regulatory protein 1 (IRP1), mitochondrial aconitase (m-aconitase) and ferrochelatase. Iron ferrochelatase Homo sapiens