Doxorubicin

H3 histone pseudogene 16 ; Homo sapiens







88 Article(s)
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1 34783124 Ginsenoside RG1 augments doxorubicin-induced apoptotic cell death in MDA-MB-231 breast cancer cell lines. 2022 Jan 1
2 34986369 Mechanisms of RPE senescence and potential role of αB crystallin peptide as a senolytic agent in experimental AMD. 2022 Feb 1
3 35053211 Cancer-Related Intracellular Signalling Pathways Activated by DOXorubicin/Cyclodextrin-Graphene-Based Nanomaterials. 2022 Jan 1 1
4 35551917 Resolvin E1 attenuates doxorubicin-induced endothelial senescence by modulating NLRP3 inflammasome activation. 2022 Jul 1
5 34504568 Role of C5a and C5aR in doxorubicin-induced cardiomyocyte senescence. 2021 Oct 1
6 34912912 Evaluation of cytotoxicity and anticancer activity of kombucha and doxorubicin combination therapy on colorectal cancer cell line HCT-116. 2021 1
7 31746354 Honokiol antagonizes doxorubicin‑induced cardiomyocyte senescence by inhibiting TXNIP‑mediated NLRP3 inflammasome activation. 2020 Jan 1
8 32340377 Arctigenin Enhances the Cytotoxic Effect of Doxorubicin in MDA-MB-231 Breast Cancer Cells. 2020 Apr 23 1
9 32478947 Cell cycle arrest and apoptosis are not dependent on p53 prior to p53-dependent embryonic stem cell differentiation. 2020 Sep 2
10 33425912 EGCG Enhanced the Anti-tumor Effect of Doxorubicine in Bladder Cancer via NF-κB/MDM2/p53 Pathway. 2020 1
11 31250942 Different sensitivities of senescent breast cancer cells to immune cell-mediated cytotoxicity. 2019 Sep 2
12 31284735 HMGB1 modulates the balance between senescence and apoptosis in response to genotoxic stress. 2019 Oct 2
13 31366086 Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation. 2019 Jul 30 1
14 31470548 Environmentally Relevant Concentrations of Bisphenol A Interact with Doxorubicin Transcriptional Effects in Human Cell Lines. 2019 Aug 29 1
15 31482012 Transcription-independent and -dependent p53-mediated apoptosis in response to genotoxic and non-genotoxic stress. 2019 1
16 32123852 Aspirin ameliorates the long-term adverse effects of doxorubicin through suppression of cellular senescence. 2019 Sep 1
17 28797827 Interaction between mTOR pathway inhibition and autophagy induction attenuates adriamycin-induced vascular smooth muscle cell senescence through decreased expressions of p53/p21/p16. 2018 Aug 2
18 29207090 Long intergenic non‑coding RNA‑p21 mediates cardiac senescence via the Wnt/β‑catenin signaling pathway in doxorubicin-induced cardiotoxicity. 2018 Feb 1
19 29416744 Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer. 2018 Jan 5 1
20 30266241 Efficacy of metformin in mediating cellular uptake and inducing apoptosis activity of doxorubicin. 2018 Nov 1
21 30274043 In vitro evaluation of a biomaterial-based anticancer drug delivery system as an alternative to conventional post-surgery bone cancer treatment. 2018 Dec 1 1
22 30405800 Low dose dinaciclib enhances doxorubicin-induced senescence in myeloma RPMI8226 cells by transformation of the p21 and p16 pathways. 2018 Nov 3
23 28011195 Protective role of klotho protein on epithelial cells upon co-culture with activated or senescent monocytes. 2017 Jan 15 1
24 28837147 Doxorubicin upregulates CXCR4 via miR-200c/ZEB1-dependent mechanism in human cardiac mesenchymal progenitor cells. 2017 Aug 24 1
25 28901484 Molecular iodine impairs chemoresistance mechanisms, enhances doxorubicin retention and induces downregulation of the CD44+/CD24+ and E-cadherin+/vimentin+ subpopulations in MCF-7 cells resistant to low doses of doxorubicin. 2017 Nov 1
26 29113274 Simvastatin potentiates doxorubicin activity against MCF-7 breast cancer cells. 2017 Nov 1
27 26590797 Modulation of DNA damage response and induction of apoptosis mediates synergism between doxorubicin and a new imidazopyridine derivative in breast and lung cancer cells. 2016 Jan 1
28 27403577 The Effect of Caffeine and chk2 Inhibitor on Doxorubicin-Induced Cellular Senescence in MCF-7 Cells. 2016 Sep 3
29 27491234 [Inhibition of Combination of Icaritin and Doxorubicin on Human Osteosarcoma MG-63 Cells in vitro]. 2016 Jun 2
30 27736799 A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence. 2016 Nov 8 1
31 27760664 [Interferon α sensitizes human osteosarcoma cells to doxorubicin-induced apoptosis through p53-dependent pathway]. 2016 Oct 11 1
32 27904675 Expression of long non-coding RNA-HOTAIR in oral squamous cell carcinoma Tca8113 cells and its associated biological behavior. 2016 2
33 24993871 Inhibitory effects of (-)-loliolide on cellular senescence in human dermal fibroblasts. 2015 1
34 25445786 Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response. 2015 Feb 1 1
35 25683911 Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells. 2015 May 2
36 26217035 c-Abl-mediated tyrosine phosphorylation of JunB is required for Adriamycin-induced expression of p21. 2015 Oct 1 7
37 26320837 Bisphenol A at the reference level counteracts doxorubicin transcriptional effects on cancer related genes in HT29 cells. 2015 Dec 1
38 26352101 Cytoprotective effects of ferritin on doxorubicin-induced breast cancer cell death. 2015 Nov 1
39 24342076 Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1.). 2014 Feb 1
40 24840054 Involvement of HIF-1α activation in the doxorubicin resistance of human osteosarcoma cells. 2014 Jul 1
41 25135721 Anti-cancer effects of novel doxorubicin prodrug PDOX in MCF-7 breast cancer cells. 2014 Aug 1
42 22674530 Inorganic phosphate enhances sensitivity of human osteosarcoma U2OS cells to doxorubicin via a p53-dependent pathway. 2013 Jan 1
43 23585524 ATM mutations uniformly lead to ATM dysfunction in chronic lymphocytic leukemia: application of functional test using doxorubicin. 2013 Jul 1
44 23607751 Mesenchymal stem cells (MSCs) from scleroderma patients (SSc) preserve their immunomodulatory properties although senescent and normally induce T regulatory cells (Tregs) with a functional phenotype: implications for cellular-based therapy. 2013 Aug 1
45 21573958 Salinomycin, a p-glycoprotein inhibitor, sensitizes radiation-treated cancer cells by increasing DNA damage and inducing G2 arrest. 2012 Aug 2
46 22134899 The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells. 2012 Apr 1
47 22305266 Cytoplasmic p21 induced by p65 prevents doxorubicin-induced cell death in pancreatic carcinoma cell line. 2012 Feb 4 5
48 22412944 Chemotherapeutic sensitization of leptomycin B resistant lung cancer cells by pretreatment with doxorubicin. 2012 1
49 23146670 Decrease of p400 ATPase complex and loss of H2A.Z within the p21 promoter occur in senescent IMR-90 human fibroblasts. 2012 Nov-Dec 1
50 23256041 Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. 2012 Dec 18 1