Phosphatidylinositols

insulin receptor substrate 1 ; Rattus norvegicus







25 Article(s)
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Pub. Year
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1 17229938 Defective insulin and acetylcholine induction of endothelial cell-nitric oxide synthase through insulin receptor substrate/Akt signaling pathway in aorta of obese rats. 2007 Apr 1
2 17579208 RhoA/Rho kinase blocks muscle differentiation via serine phosphorylation of insulin receptor substrate-1 and -2. 2007 Sep 1
3 16899578 Up-regulation of the phosphatidylinositol 3-kinase/protein kinase B pathway in the ovary of rats by chronic treatment with hCG and insulin. 2006 Aug 1
4 15127200 Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase. 2004 May 1
5 15134463 In vitro phosphorylation of insulin receptor substrate 1 by protein kinase C-zeta: functional analysis and identification of novel phosphorylation sites. 2004 May 18 1
6 12453826 Reversal of denervation-induced insulin resistance by SHIP2 protein synthesis blockade. 2003 Apr 1
7 12031952 Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes. 2002 Jun 2
8 12112939 Elevated fasting insulin concentrations associate with impaired insulin signaling in skeletal muscle of healthy subjects independent of obesity. 2002 May-Jun 2
9 11121098 Involvement of insulin receptor substrates in epidermal growth factor induced activation of phosphatidylinositol 3-kinase in rat hepatocyte primary culture. 2001 Jan 1
10 11287365 Inhibitory effect of hyperglycemia on insulin-induced Akt/protein kinase B activation in skeletal muscle. 2001 May 1
11 11574414 Thiazolidinedione treatment prevents free fatty acid-induced insulin resistance in male wistar rats. 2001 Oct 1
12 10749857 Thiazolidinedione treatment enhances insulin effects on protein kinase C-zeta /lambda activation and glucose transport in adipocytes of nondiabetic and Goto-Kakizaki type II diabetic rats. 2000 Jun 2 1
13 10924365 Insulin activation of mitogen-activated protein (MAP) kinase and Akt is phosphatidylinositol 3-kinase-dependent in rat adipocytes. 2000 Aug 11 1
14 9892238 Enhanced insulin-stimulated activation of phosphatidylinositol 3-kinase in the liver of high-fat-fed rats. 1999 Jan 1
15 10078575 Muscle fiber type-specific defects in insulin signal transduction to glucose transport in diabetic GK rats. 1999 Mar 1
16 10581198 Hyperglycemia impairs the insulin signaling step between PI 3-kinase and Akt/PKB activations in ZDF rat liver. 1999 Dec 9 1
17 9421369 Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats. 1998 Jan 2
18 9605931 Insulin receptor substrate (IRS) proteins IRS-1 and IRS-2 differential signaling in the insulin/insulin-like growth factor-I pathways in fetal brown adipocytes. 1998 May 2
19 9792680 Different subcellular distribution and regulation of expression of insulin receptor substrate (IRS)-3 from those of IRS-1 and IRS-2. 1998 Nov 6 1
20 9794462 The new antidiabetic drug MCC-555 acutely sensitizes insulin signaling in isolated cardiomyocytes. 1998 Nov 1
21 9139749 Insulin receptor substrate (IRS)-2 is dephosphorylated more rapidly than IRS-1 via its association with phosphatidylinositol 3-kinase in skeletal muscle cells. 1997 May 9 1
22 9392479 Effect of captopril, losartan, and bradykinin on early steps of insulin action. 1997 Dec 2
23 7791763 Molecular cloning of an amphibian insulin receptor substrate 1-like cDNA and involvement of phosphatidylinositol 3-kinase in insulin-induced Xenopus oocyte maturation. 1995 Jul 1
24 7513124 Activation of PI 3-kinase in 3T3-L1 adipocytes by association with insulin receptor substrate-1. 1994 Mar 1
25 8144649 Mutation of the two carboxyl-terminal tyrosines in the insulin receptor results in enhanced activation of mitogen-activated protein kinase. 1994 Apr 8 1