Serine

insulin receptor substrate 1 ; Rattus norvegicus







141 Article(s)
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1 34855213 Antidiabetic effects of quercetin and liraglutide combination through modulation of TXNIP/IRS-1/PI3K pathway. 2022 Jan 2
2 33824679 Mechanism of Electroacupuncture Regulating IRS-1 Phosphorylation in Skeletal Muscle to Improve Insulin Sensitivity. 2021 2
3 34119519 Linagliptin, a DPP-4 inhibitor, ameliorates Aβ (1-42) peptides induced neurodegeneration and brain insulin resistance (BIR) via insulin receptor substrate-1 (IRS-1) in rat model of Alzheimer's disease. 2021 Sep 1 2
4 34684891 d-Allulose Ameliorates Skeletal Muscle Insulin Resistance in High-Fat Diet-Fed Rats. 2021 Oct 19 1
5 32196625 Effects of aging and life-long moderate calorie restriction on IL-15 signaling in the rat white adipose tissue. 2020 Mar 1
6 32444657 Enhanced skeletal muscle insulin sensitivity after acute resistance-type exercise is upregulated by rapamycin-sensitive mTOR complex 1 inhibition. 2020 May 22 2
7 32898530 Asymmetrical dimethylarginine induces dysfunction of insulin signal transduction via endoplasmic reticulum stress in the liver of diabetic rats. 2020 Nov 1 1
8 33159675 miR-155-5p alleviates ethanol-induced myocardial insulin resistance in H9C2 cells via regulating the mTOR signalling pathway. 2020 Dec 2
9 30463045 Neuroprotective role of astaxanthin in hippocampal insulin resistance induced by Aβ peptides in animal model of Alzheimer's disease. 2019 Feb 2
10 30620715 Metformin improves ovarian insulin signaling alterations caused by fetal programming. 2019 Jan 1 1
11 31005715 Rare ginsenosides ameliorate lipid overload-induced myocardial insulin resistance via modulating metabolic flexibility. 2019 May 1
12 31137621 Chenodeoxycholic Acid Ameliorates AlCl3-Induced Alzheimer's Disease Neurotoxicity and Cognitive Deterioration via Enhanced Insulin Signaling in Rats. 2019 May 24 2
13 31152848 Study on the metabolism toxicity, susceptibility and mechanism of di-(2-ethylhexyl) phthalate on rat liver BRL cells with insulin resistance in vitro. 2019 Jun 15 1
14 29154269 Early and Persistent O-GlcNAc Protein Modification in the Streptozotocin Model of Alzheimer's Disease. 2018 1
15 29248832 Polyphenol-rich ethyl acetate fraction isolated from Molineria latifolia ameliorates insulin resistance in experimental diabetic rats via IRS1/AKT activation. 2018 Feb 1
16 29490092 Blueberry Supplementation Influences the Gut Microbiota, Inflammation, and Insulin Resistance in High-Fat-Diet-Fed Rats. 2018 Feb 1 2
17 29551354 The antipsychotics sulpiride induces fatty liver in rats via phosphorylation of insulin receptor substrate-1 at Serine 307-mediated adipose tissue insulin resistance. 2018 Apr 15 1
18 30115876 Hepatoprotective Effects of MHY3200 on High-Fat, Diet-Induced, Non-Alcoholic Fatty Liver Disease in Rats. 2018 Aug 16 1
19 27180072 Glutamate Inhibits the Pro-Survival Effects of Insulin-Like Growth Factor-1 on Retinal Ganglion Cells in Hypoxic Neonatal Rat Retina. 2017 Jul 1
20 28059465 Rosmarinic Acid Mediates Mitochondrial Biogenesis in Insulin Resistant Skeletal Muscle Through Activation of AMPK. 2017 Jul 1
21 28505381 Insulin Resistance Disrupts the Interaction Between AKT and the NMDA Receptor and the Inactivation of the CaMKIV/CREB Pathway in Minimal Hepatic Encephalopathy. 2017 Oct 1 1
22 29043342 Antihypertensive effects of Tartary buckwheat flavonoids by improvement of vascular insulin sensitivity in spontaneously hypertensive rats. 2017 Nov 15 2
23 26205216 Duodenal-Jejunal Bypass Surgery Ameliorates Glucose Homeostasis and Reduces Endoplasmic Reticulum Stress in the Liver Tissue in a Diabetic Rat Model. 2016 May 2
24 26713546 Curcumin prevents inflammatory response, oxidative stress and insulin resistance in high fructose fed male Wistar rats: Potential role of serine kinases. 2016 Jan 25 1
25 27185631 Endoplasmic reticulum stress mediates JNK-dependent IRS-1 serine phosphorylation and results in Tau hyperphosphorylation in amyloid β oligomer-treated PC12 cells and primary neurons. 2016 Aug 10 5
26 27250532 Withaferin A protects against palmitic acid-induced endothelial insulin resistance and dysfunction through suppression of oxidative stress and inflammation. 2016 Jun 2 1
27 27519467 LncRNA NONRATT021972 siRNA rescued decreased heart rate variability in diabetic rats in superior cervical ganglia. 2016 Dec 1
28 25268311 JNK and IKKβ phosphorylation is reduced by glucocorticoids in adipose tissue from insulin-resistant rats. 2015 Jan 1
29 25883115 Wnt Signaling Regulates Blood Pressure by Downregulating a GSK-3β-Mediated Pathway to Enhance Insulin Signaling in the Central Nervous System. 2015 Oct 1
30 25978724 Endoplasmic reticulum stress impairs insulin receptor signaling in the brains of obese rats. 2015 2
31 26027876 Periapical Lesions Decrease Insulin Signaling in Rat Skeletal Muscle. 2015 Aug 1
32 26084330 L-Citrulline increases hepatic sensitivity to insulin by reducing the phosphorylation of serine 1101 in insulin receptor substrate-1. 2015 Jun 18 2
33 26455923 Resveratrol prevents insulin resistance caused by short-term elevation of free fatty acids in vivo. 2015 Nov 3
34 24314869 Effects of a Lactobacillus paracasei B21060 based synbiotic on steatosis, insulin signaling and toll-like receptor expression in rats fed a high-fat diet. 2014 Jan 1
35 24389792 Hepatic inflammation induced by high-fructose diet is associated with altered 11βHSD1 expression in the liver of Wistar rats. 2014 Sep 2
36 24704288 Oleanolic acid supplement attenuates liquid fructose-induced adipose tissue insulin resistance through the insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt signaling pathway in rats. 2014 Jun 1 3
37 24728905 Duodenal-Jejunal bypass improves glucose homeostasis in association with decreased proinflammatory response and activation of JNK in the liver and adipose tissue in a T2DM rat model. 2014 Sep 2
38 24788483 Gender differences in the expression and cellular localization of lipin 1 in the hearts of fructose-fed rats. 2014 Jul 1
39 24896641 Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells. 2014 1
40 24961241 Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation. 2014 Aug 15 1
41 24997070 Amino acid-induced impairment of insulin sensitivity in healthy and obese rats is reversible. 2014 Jul 1 1
42 25352752 Serine 307 on insulin receptor substrate 1 is required for SOCS3 and TNF-α signaling in the rMC-1 cell line. 2014 1
43 22901685 Positive and negative regulation of insulin action by genistein in the endothelium. 2013 Jan 1
44 23279876 Hyperglycemia is associated with enhanced gluconeogenesis in a rat model of permanent cerebral ischemia. 2013 Mar 10 1
45 23328071 Duration of rise in free fatty acids determines salicylate's effect on hepatic insulin sensitivity. 2013 Apr 1
46 23840461 Tectorigenin Attenuates Palmitate-Induced Endothelial Insulin Resistance via Targeting ROS-Associated Inflammation and IRS-1 Pathway. 2013 1
47 23840732 Huang-lian-jie-du-tang protects rats from cardiac damages induced by metabolic disorder by improving inflammation-mediated insulin resistance. 2013 3
48 23968580 Developmental programming in skeletal muscle in response to overnourishment in the immediate postnatal life in rats. 2013 Nov 1
49 23975131 Jiaotai Pill enhances insulin signaling through phosphatidylinositol 3-kinase pathway in skeletal muscle of diabetic rats. 2013 Sep 1
50 24036112 Insulin activates RSK (p90 ribosomal S6 kinase) to trigger a new negative feedback loop that regulates insulin signaling for glucose metabolism. 2013 Oct 25 8