| 1 |
35418949 | Can Digenic, Tri-Allelic Inheritance of Variants in STAR and CYP11A1 Give Rise to Primary Adrenal Insufficiency? A Case Report. | 2022 |
1 |
| 2 |
34015388 | Neurosteroidogenic enzymes: CYP11A1 in the central nervous system. | 2021 Jul |
1 |
| 3 |
34231171 | Association Analysis of CYP11A1 Variants with Polycystic Ovary Syndrome: a Case-Control Study from North India. | 2021 Oct |
4 |
| 4 |
34563259 | The role of polymorphism in various potential genes on polycystic ovary syndrome susceptibility and pathogenesis. | 2021 Sep 26 |
1 |
| 5 |
31936362 | Establishment of A Reversibly Inducible Porcine Granulosa Cell Line. | 2020 Jan 8 |
1 |
| 6 |
32645328 | The interactions of a number of steroid-metabolizing cytochromes P450 with abiraterone D4A metabolite: spectral analysis and molecular docking. | 2020 Oct |
1 |
| 7 |
32867102 | Characterization of Two Novel Variants of the Steroidogenic Acute Regulatory Protein Identified in a Girl with Classic Lipoid Congenital Adrenal Hyperplasia. | 2020 Aug 27 |
1 |
| 8 |
33290750 | Expression of ARID1A in polycystic ovary syndrome and its effect on the proliferation and apoptosis of ovarian granulosa cells. | 2020 Dec |
1 |
| 9 |
33659272 | CYP11A1 Upregulation Leads to Trophoblast Oxidative Stress and Fetal Neurodevelopmental Toxicity That can be Rescued by Vitamin D. | 2020 |
3 |
| 10 |
30272820 | Polycistronic expression of the mitochondrial steroidogenic P450scc system in the HEK293T cell line. | 2019 Mar |
1 |
| 11 |
30611420 | Classic congenital adrenal hyperplasia and its impact on reproduction. | 2019 Jan |
1 |
| 12 |
31671693 | Novel Mutations Segregating with Complete Androgen Insensitivity Syndrome and their Molecular Characteristics. | 2019 Oct 30 |
1 |
| 13 |
31741382 | Quantum-Mechanical/Molecular-Mechanical Studies of CYP11A1-Catalyzed Biosynthesis of Pregnenolone from Cholesterol Reveal a C-C Bond Cleavage Reaction That Occurs by a Compound I-Mediated Electron Transfer. | 2019 Dec 26 |
2 |
| 14 |
29228121 | Low-dose bisphenol A activates the ERK signaling pathway and attenuates steroidogenic gene expression in human placental cells. | 2018 Feb 1 |
2 |
| 15 |
28991453 | Active Site Structures of CYP11A1 in the Presence of Its Physiological Substrates and Alterations upon Binding of Adrenodoxin. | 2017 Oct 31 |
1 |
| 16 |
29143658 | A key enzyme of animal steroidogenesis can function in plants enhancing their immunity and accelerating the processes of growth and development. | 2017 Nov 14 |
4 |
| 17 |
29178636 | A novel splice site variant in CYP11A1 in trans with the p.E314K variant in a male patient with congenital adrenal insufficiency. | 2017 Nov |
1 |
| 18 |
26432395 | Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution. | 2016 Jan |
1 |
| 19 |
26658226 | Metabolism of Oral Turinabol by Human Steroid Hormone-Synthesizing Cytochrome P450 Enzymes. | 2016 Feb |
1 |
| 20 |
26704533 | Preliminary evidence of altered steroidogenesis in women with Alzheimer's disease: Have the patients "OLDER" adrenal zona reticularis? | 2016 Apr |
1 |
| 21 |
26839092 | Products of gut-microbial tryptophan metabolism inhibit the steroid hormone-synthesizing cytochrome P450 11A1. | 2016 Aug |
1 |
| 22 |
27512005 | Effect of adiponectin on the steroidogenic acute regulatory protein, P450 side chain cleavage enzyme and 3β-hydroxysteroid dehydrogenase gene expression, progesterone and androstenedione production by the porcine uterus during early pregnancy. | 2016 Jun |
1 |
| 23 |
27571509 | Isotope-Labeling Studies Support the Electrophilic Compound I Iron Active Species, FeO(3+), for the Carbon-Carbon Bond Cleavage Reaction of the Cholesterol Side-Chain Cleavage Enzyme, Cytochrome P450 11A1. | 2016 Sep 21 |
1 |
| 24 |
31968797 | Membrane-Mediated Protein-Protein Interactions of Cholesterol Side-Chain Cleavage Cytochrome P450 with its Associated Electron Transport Proteins. | 2016 Sep |
3 |
| 25 |
25448732 | Novel activities of CYP11A1 and their potential physiological significance. | 2015 Jul |
1 |
| 26 |
25724481 | Transcriptional activation of LON Gene by a new form of mitochondrial stress: A role for the nuclear respiratory factor 2 in StAR overload response (SOR). | 2015 Jun 15 |
4 |
| 27 |
25988614 | On the role of skin in the regulation of local and systemic steroidogenic activities. | 2015 Nov |
1 |
| 28 |
26374826 | Synthesis of an Endogenous Steroidal Na Pump Inhibitor Marinobufagenin, Implicated in Human Cardiovascular Diseases, Is Initiated by CYP27A1 via Bile Acid Pathway. | 2015 Oct |
1 |
| 29 |
26603348 | Evidence That Compound I Is the Active Species in Both the Hydroxylase and Lyase Steps by Which P450scc Converts Cholesterol to Pregnenolone: EPR/ENDOR/Cryoreduction/Annealing Studies. | 2015 Dec 8 |
2 |
| 30 |
23869782 | Cytochromes p450 and skin cancer: role of local endocrine pathways. | 2014 Jan |
1 |
| 31 |
25137424 | Intra-tissue steroid profiling indicates differential progesterone and testosterone metabolism in the endometrium and endometriosis lesions. | 2014 Nov |
1 |
| 32 |
25525990 | Pregnenolone functions in centriole cohesion during mitosis. | 2014 Dec 18 |
1 |
| 33 |
23089212 | Inhibition and stimulation of activity of purified recombinant CYP11A1 by therapeutic agents. | 2013 May 22 |
1 |
| 34 |
23357790 | The spatial and temporal regulation of the hormonal signal. Role of mitochondria in the formation of a protein complex required for the activation of cholesterol transport and steroids synthesis. | 2013 May 22 |
1 |
| 35 |
23555723 | Abnormal apoptosis of trophoblastic cells is related to the up-regulation of CYP11A gene in placenta of preeclampsia patients. | 2013 |
1 |
| 36 |
23769709 | Mitochondria and mammalian reproduction. | 2013 Oct 15 |
1 |
| 37 |
23913445 | Rapid impact of progesterone on the neuronal growth cone. | 2013 Oct |
1 |
| 38 |
22606018 | Risk-association of CYP11A1 polymorphisms and breast cancer among Han Chinese women in Southern China. | 2012 |
1 |
| 39 |
22673022 | Left ventricular structure and function in relation to steroid biosynthesis genes in a white population. | 2012 Sep |
1 |
| 40 |
22951915 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome. | 2012 Dec |
1 |
| 41 |
22986075 | Structure-activity relationship (SAR) analysis of a family of steroids acutely controlling steroidogenesis. | 2012 Nov |
2 |
| 42 |
23039857 | Compound I is the reactive intermediate in the first monooxygenation step during conversion of cholesterol to pregnenolone by cytochrome P450scc: EPR/ENDOR/cryoreduction/annealing studies. | 2012 Oct 17 |
2 |
| 43 |
23155436 | Cholesterol side-chain cleavage gene expression in theca cells: augmented transcriptional regulation and mRNA stability in polycystic ovary syndrome. | 2012 |
1 |
| 44 |
21159775 | Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1. | 2011 Feb 18 |
1 |
| 45 |
21195129 | Regulation of steroid production: analysis of Cyp11a1 promoter. | 2011 Apr 10 |
2 |
| 46 |
21520051 | Differential regulation of the human CYP11A1 promoter in mouse brain and adrenals. | 2011 Aug |
1 |
| 47 |
21526428 | Kinetic and optical biosensor study of adrenodoxin mutant AdxS112W displaying an enhanced interaction towards the cholesterol side chain cleavage enzyme (CYP11A1). | 2011 Dec |
1 |
| 48 |
21868758 | Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors. | 2011 Oct 15 |
1 |
| 49 |
19360465 | BRCA1-associated breast and ovarian cancer risks in Poland: no association with commonly studied polymorphisms. | 2010 Jan |
1 |
| 50 |
20233795 | Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells. | 2010 May |
1 |