Vincristine

cytochrome P450 family 3 subfamily A member 5 ; Homo sapiens







19 Article(s)
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Pub. Year
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1 34561358 Pharmacogenomics insights into precision pediatric oncology. 2021 Dec 1 1
2 29115708 CYP3A5 genotype and its impact on vincristine pharmacokinetics and development of neuropathy in Kenyan children with cancer. 2018 Mar 1
3 29502215 Identification of a less toxic vinca alkaloid derivative for use as a chemotherapeutic agent, based on in silico structural insights and metabolic interactions with CYP3A4 and CYP3A5. 2018 Mar 4 5
4 30429697 Severe Neuropathic Pain With Concomitant Administration of Vincristine and Posaconazole. 2018 Sep-Oct 1
5 28697165 Association of CYP3A5 Expression and Vincristine Neurotoxicity in Pediatric Malignancies in Turkish Population. 2017 Aug 2
6 25305360 The effect of race on the CYP3A-mediated metabolism of vincristine in pediatric patients with acute lymphoblastic leukemia. 2016 Feb 3
7 26565076 Severe Vincristine-induced Neuropathic Pain in a CYP3A5 Nonexpressor With Reduced CYP3A4/5 Activity: Case Study. 2016 Jan 1 6
8 25634447 Differential Interactions of Cytochrome P450 3A5 and 3A4 with Chemotherapeutic Agent-Vincristine: A Comparative Molecular Dynamics Study. 2015 11
9 24484539 Comparison of catalytic properties of cytochromes P450 3A4 and 3A5 by molecular docking simulation. 2014 2
10 23780963 The relative contributions of CYP3A4 and CYP3A5 to the metabolism of vinorelbine. 2013 Sep 1
11 21225912 Increased risk of vincristine neurotoxicity associated with low CYP3A5 expression genotype in children with acute lymphoblastic leukemia. 2011 Mar 6
12 21968951 Impact of plasma and intracellular exposure and CYP3A4, CYP3A5, and ABCB1 genetic polymorphisms on vincristine-induced neurotoxicity. 2011 Dec 2
13 19757141 Paralytic ileus possibly associated with interaction between ritonavir/lopinavir and vincristine. 2009 Dec 1
14 18085684 Effect of race on vincristine-associated neurotoxicity in pediatric acute lymphoblastic leukemia patients. 2008 Apr 5
15 18650247 Apparent high CYP3A5 expression is required for significant metabolism of vincristine by human cryopreserved hepatocytes. 2008 Oct 4
16 17272675 Effect of CYP3A5 expression on vincristine metabolism with human liver microsomes. 2007 May 12
17 16679390 Selective metabolism of vincristine in vitro by CYP3A5. 2006 Aug 3
18 16188140 [Transfection of HL-60 cells with CYP3A5 gene induces drug-resistant phenotype]. 2005 Aug 1
19 12859862 [Study of CYP3A5 in drug resistance mechanisms in acute leukemia]. 2003 Jun 1