Guanine Nucleotides

ras homolog family member A ; Homo sapiens







86 Article(s)
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Pub. Year
#Total Relationships
1 34663953 Microtubules tune mechanosensitive cell responses. 2022 Mar 1
2 32808262 Identification of Rho GEF and RhoA Activation by Pull-Down Assays. 2021 1
3 33126816 Regulation and functions of the RhoA regulatory guanine nucleotide exchange factor GEF-H1. 2021 Sep-Nov 1
4 33465404 Cdk1 phosphorylation negatively regulates the activity of Net1 towards RhoA during mitosis. 2021 Apr 1
5 33762326 The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway. 2021 Apr 15 1
6 33948992 Tumor necrosis factor-induced ArhGEF10 selectively activates RhoB contributing to human microvascular endothelial cell tight junction disruption. 2021 Jun 1
7 34427245 Whole-exome sequencing identifies multiple pathogenic variants in a large South Indian family with primary open-angle glaucoma. 2021 Sep 1
8 35174167 Role of ARHGEF3 as a GEF and mTORC2 Regulator. 2021 1
9 32619481 A Non-canonical BRCT-Phosphopeptide Recognition Mechanism Underlies RhoA Activation in Cytokinesis. 2020 Aug 17 2
10 31089935 DBS is activated by EPHB2/SRC signaling-mediated tyrosine phosphorylation in HEK293 cells. 2019 Sep 1
11 31197859 Exploring the systematic effect of N-substituted PxxP motifs on peptoid affinity to ARHGEF5/TIM SH3 domain and its relationship with ARHGEF5/TIM activation. 2019 Nov 1
12 31431179 Mechanotransduction: from the cell surface to the nucleus via RhoA. 2019 Aug 19 1
13 31490066 Interconnecting Flexibility, Structural Communication, and Function in RhoGEF Oncoproteins. 2019 Oct 28 1
14 29373579 An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. 2018 1
15 29377108 Regulation of RhoA GTPase and various transcription factors in the RhoA pathway. 2018 Sep 2
16 29410088 Mapping Interactions between p27 and RhoA that Stimulate Cell Migration. 2018 Mar 16 2
17 28884018 PP2A-B' holoenzyme substrate recognition, regulation and role in cytokinesis. 2017 1
18 26719334 Structural and Mechanistic Insights into the Regulation of the Fundamental Rho Regulator RhoGDIα by Lysine Acetylation. 2016 Mar 11 1
19 28036092 Human Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) Regulates Dendritic Morphogenesis. 2016 Dec 29 1
20 25381061 HGAL localization to cell membrane regulates B-cell receptor signaling. 2015 Jan 22 1
21 25494542 ARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias. 2015 1
22 25645980 The auto-inhibitory state of Rho guanine nucleotide exchange factor ARHGEF5/TIM can be relieved by targeting its SH3 domain with rationally designed peptide aptamers. 2015 Apr 1
23 26103434 G17V RHOA: Genetic evidence of GTP-unbound RHOA playing a role in tumorigenesis in T cells. 2015 1
24 24467208 Regulation of RhoA activity by adhesion molecules and mechanotransduction. 2014 Feb 1
25 24607953 The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration. 2014 1
26 24958816 Gα13/PDZ-RhoGEF/RhoA signaling is essential for gastrin-releasing peptide receptor-mediated colon cancer cell migration. 2014 Sep 1
27 25321414 The RhoGEF Net1 is required for normal mammary gland development. 2014 Dec 1
28 23512329 Expression of p114RhoGEF predicts lymph node metastasis and poor survival of squamous-cell lung carcinoma patients. 2013 Jun 1
29 23531275 Determinants at the N- and C-termini of Gα12 required for activation of Rho-mediated signaling. 2013 Mar 25 2
30 23816534 Modification of p115RhoGEF Ser(330) regulates its RhoGEF activity. 2013 Nov 1
31 24345679 PLCε, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart. 2013 Dec 17 1
32 22238672 The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion. 2012 1
33 22911862 Identification of a novel actin-binding domain within the Rho guanine nucleotide exchange factor TEM4. 2012 1
34 22949735 FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility. 2012 Sep 4 1
35 22172673 Targeting of the RhoGEF Ect2 to the equatorial membrane controls cleavage furrow formation during cytokinesis. 2011 Dec 13 1
36 20018863 Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics. 2010 Feb 19 1
37 20348106 Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation. 2010 May 21 1
38 20844236 HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway. 2010 Dec 9 3
39 20878268 RHO GTPase signaling for axon extension: is prenylation important? 2010 Oct 1
40 19196702 High-throughput screening for small-molecule inhibitors of LARG-stimulated RhoA nucleotide binding via a novel fluorescence polarization assay. 2009 Feb 2
41 19586902 Interaction of the RhoA exchange factor Net1 with discs large homolog 1 protects it from proteasome-mediated degradation and potentiates Net1 activity. 2009 Sep 4 1
42 18211802 ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA. 2008 Mar 28 2
43 18320579 Reversible translocation of p115-RhoGEF by G(12/13)-coupled receptors. 2008 Aug 1 1
44 18765661 Dual activation of phospholipase C-epsilon by Rho and Ras GTPases. 2008 Oct 31 1
45 17273773 Diverse activation states of RhoA in human lung cancer cells: contribution of G protein coupled receptors. 2007 Mar 1
46 17279591 Bivalent peptides as models for multimeric targets of PDZ domains. 2007 Mar 5 2
47 17702745 Regulation of ephexin1, a guanine nucleotide exchange factor of Rho family GTPases, by fibroblast growth factor receptor-mediated tyrosine phosphorylation. 2007 Oct 19 1
48 17950529 Sema4D-plexin-B1 implicated in regulation of dendritic spine density through RhoA/ROCK pathway. 2007 Nov 20 1
49 16411892 RhoA/Rho-kinase in erectile tissue: mechanisms of disease and therapeutic insights. 2006 Feb 1
50 16472676 Degradation of RhoA by Smurf1 ubiquitin ligase. 2006 2