Title : Determinants at the N- and C-termini of Gα12 required for activation of Rho-mediated signaling.

Pub. Date : 2013 Mar 25

PMID : 23531275






2 Functional Relationships(s)
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1 BACKGROUND: Heterotrimeric guanine nucleotide binding proteins of the G12/13 subfamily, which includes the alpha-subunits Galpha12 and Galpha13, stimulate the monomeric G protein RhoA through interaction with a distinct subset of Rho-specific guanine nucleotide exchange factors (RhoGEFs). Guanine Nucleotides ras homolog family member A Homo sapiens
2 BACKGROUND: Heterotrimeric guanine nucleotide binding proteins of the G12/13 subfamily, which includes the alpha-subunits Galpha12 and Galpha13, stimulate the monomeric G protein RhoA through interaction with a distinct subset of Rho-specific guanine nucleotide exchange factors (RhoGEFs). Guanine Nucleotides ras homolog family member A Homo sapiens