Guanosine Diphosphate

ras homolog family member A ; Homo sapiens







82 Article(s)
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1 35215978 Vav Proteins in Development of the Brain: A Potential Relationship to the Pathogenesis of Congenital Zika Syndrome? 2022 Feb 14 1
2 35583642 Targeting Cancer by Using Nanoparticles to Modulate RHO GTPase Signaling. 2022 1
3 32808262 Identification of Rho GEF and RhoA Activation by Pull-Down Assays. 2021 3
4 33497604 Structure of an inactive conformation of GTP-bound RhoA GTPase. 2021 Jun 3 3
5 34304710 Regulation of Leukaemia Associated Rho GEF (LARG/ARHGEF12). 2021 Jul 25 1
6 34551282 KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis. 2021 Nov 18 1
7 34709522 Assembly of the Non-Canonical Myo9a-RhoGAP and RhoA·GDP Transition State Complex in the Presence of MgF3. 2021 Dec 1
8 32483387 Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma. 2020 Jul 1
9 31490066 Interconnecting Flexibility, Structural Communication, and Function in RhoGEF Oncoproteins. 2019 Oct 28 2
10 29196061 Direct regulation of p190RhoGEF by activated Rho and Rac GTPases. 2018 Apr 3
11 29373579 An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. 2018 1
12 29410088 Mapping Interactions between p27 and RhoA that Stimulate Cell Migration. 2018 Mar 16 1
13 29940100 SmgGDS-607 Regulation of RhoA GTPase Prenylation Is Nucleotide-Dependent. 2018 Jul 24 4
14 28150077 The structure of a small GTPaseRhoA in complex with PDZRhoGEF and the inhibitor HL47. 2017 May 3
15 29061365 Rho-specific Guanine nucleotide exchange factors (Rho-GEFs) inhibition affects macrophage phenotype and disrupts Golgi complex. 2017 Dec 2
16 26574607 Variegated RHOA mutations in adult T-cell leukemia/lymphoma. 2016 Feb 4 2
17 26695096 RhoGDIα Acetylation at K127 and K141 Affects Binding toward Nonprenylated RhoA. 2016 Jan 19 1
18 26822702 (19)F NMR and DFT Analysis Reveal Structural and Electronic Transition State Features for RhoA-Catalyzed GTP Hydrolysis. 2016 Mar 1 1
19 27363609 Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism. 2016 Jul 31 1
20 27628050 Rho GTPases: Regulation and roles in cancer cell biology. 2016 Oct 2
21 27756879 C5a receptor (CD88) promotes motility and invasiveness of gastric cancer by activating RhoA. 2016 Dec 20 8
22 27992599 RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress. 2016 1
23 26067270 Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure. 2015 Aug 7 3
24 24505392 Automated NMR fragment based screening identified a novel interface blocker to the LARG/RhoA complex. 2014 3
25 25186459 The crystal structure of the RhoA-AKAP-Lbc DH-PH domain complex. 2014 Dec 1 1
26 23322732 Balanced Tiam1-rac1 and RhoA drives proliferation and invasion of pancreatic cancer cells. 2013 Mar 2
27 23405219 CYLD regulates RhoA activity by modulating LARG ubiquitination. 2013 1
28 23493395 Activated RhoA is a positive feedback regulator of the Lbc family of Rho guanine nucleotide exchange factor proteins. 2013 Apr 19 2
29 24067935 ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding. 2013 Nov 1
30 21993423 Effect of curcumin on irradiated and estrogen-transformed human breast cell lines. 2012 Feb 2
31 22628549 Quantitative analysis of prenylated RhoA interaction with its chaperone, RhoGDI. 2012 Aug 3 3
32 21064165 Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF. 2011 Jan 1
33 21816819 Insights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF. 2011 Oct 7 2
34 21886810 APC(cdh1) mediates degradation of the oncogenic Rho-GEF Ect2 after mitosis. 2011 2
35 20018869 Real-time NMR study of guanine nucleotide exchange and activation of RhoA by PDZ-RhoGEF. 2010 Feb 19 1
36 20709748 Splice variants of SmgGDS control small GTPase prenylation and membrane localization. 2010 Nov 12 1
37 20739463 Expression of the Salmonella spp. virulence factor SifA in yeast alters Rho1 activity on peroxisomes. 2010 Oct 15 1
38 20844236 HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway. 2010 Dec 9 3
39 19515453 Constitutively active RhoA inhibits proliferation by retarding G(1) to S phase cell cycle progression and impairing cytokinesis. 2009 Sep 1
40 19654316 A novel protein associated with membrane-type 1 matrix metalloproteinase binds p27(kip1) and regulates RhoA activation, actin remodeling, and matrigel invasion. 2009 Oct 2 1
41 19789809 Photochemically induced increase in endothelial permeability regulated by RhoA activation. 2009 Oct 2
42 18524772 RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha. 2008 Aug 1 2
43 18660502 ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells. 2008 Oct 3 1
44 17272280 p200 RhoGAP promotes cell proliferation by mediating cross-talk between Ras and Rho signaling pathways. 2007 Mar 23 2
45 16354763 Angiotensin II up-regulates the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF), a regulator of G protein signaling domain-containing RhoGEF, in vascular smooth muscle cells. 2006 Mar 1
46 16411892 RhoA/Rho-kinase in erectile tissue: mechanisms of disease and therapeutic insights. 2006 Feb 1
47 16472676 Degradation of RhoA by Smurf1 ubiquitin ligase. 2006 1
48 17019437 Novel peptide recognized by RhoA GTPase. 2006 2
49 16112081 GrinchGEF--a novel Rho-specific guanine nucleotide exchange factor. 2005 Oct 7 1
50 16182110 Reduced mRNA and protein content of rho guanine nucleotide exchange factor (RhoGEF) in Bartter's and Gitelman's syndromes: relevance for the pathophysiology of hypertension. 2005 Sep 3