Dexamethasone

tumor protein p53 ; Homo sapiens







42 Article(s)
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1 35478958 Hesperidin Ameliorates Dexamethasone-Induced Osteoporosis by Inhibiting p53. 2022 2
2 32272509 Dexamethasone Interferes with Autophagy and Affects Cell Survival in Irradiated Malignant Glioma Cells. 2020 Sep 1
3 33425404 Efficacy of Venetoclax and Dexamethasone in Refractory IgM Primary Plasma Cell Leukemia with t(11;14) and TP53 Mutation: A Case Report and Literature Review. 2020 1
4 30375484 Chronic p27Kip1 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor. 2018 Oct 30 1
5 28755014 Significance of glucocorticoid receptor expression in patients with non-small cell lung cancer treated with pemetrexed-based chemotherapy. 2017 Oct 1
6 28918747 Omega-3 Polyunsaturated Fatty Acids Eicosapentaenoic Acid and Docosahexaenoic Acid Enhance Dexamethasone Sensitivity in Multiple Myeloma Cells by the p53/miR-34a/Bcl-2 Axis. 2017 Jul 4
7 23727633 Glucocorticoids induce senescence in primary human tenocytes by inhibition of sirtuin 1 and activation of the p53/p21 pathway: in vivo and in vitro evidence. 2014 Jul 4
8 24736075 Glucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexed. 2014 Apr 2
9 23759586 Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression. 2013 Jul 1 3
10 22773829 Glucocorticoid receptor activation inhibits p53-induced apoptosis of MCF10Amyc cells via induction of protein kinase Cε. 2012 Aug 24 1
11 23272171 Dexamethasone reduces sensitivity to cisplatin by blunting p53-dependent cellular senescence in non-small cell lung cancer. 2012 3
12 20878126 Thalidomide enhances cyclophosphamide and dexamethasone-mediated cytotoxicity towards cultured chronic lymphocytic leukaemia cells. 2010 Nov 1
13 12519780 Identification of a functional link for the p53 tumor suppressor protein in dexamethasone-induced growth suppression. 2003 Mar 14 3
14 14555213 Pleiotropic anti-apoptotic activity of glucocorticoids in ovarian follicular cells. 2003 Oct 15 2
15 11139340 p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma. 2001 Jan 15 1
16 11159853 Glucocorticoids protect against apoptosis induced by serum deprivation, cyclic adenosine 3',5'-monophosphate and p53 activation in immortalized human granulosa cells: involvement of Bcl-2. 2001 Feb 4
17 11295047 Synergistic effects of dexamethasone and genistein on the expression of Cdk inhibitor p21WAF1/CIP1 in human hepatocellular and colorectal carcinoma cells. 2001 May 1
18 11350911 Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents. 2001 May 3
19 11498783 Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo. 2001 Aug 2 2
20 11562347 Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2. 2001 Sep 15 5
21 11677114 Steroid-mediated inhibition of radiation-induced apoptosis in C4-1 cervical carcinoma cells is p53-dependent. 2001 Nov 1
22 10654447 Polyamine-depletion induces p27Kip1 and enhances dexamethasone-induced G1 arrest and apoptosis in human T lymphoblastic leukemia cells. 2000 Feb 1
23 10817508 Inhibition of radiation-induced apoptosis by dexamethasone in cervical carcinoma cell lines depends upon increased HPV E6/E7. 2000 May 2
24 11080152 Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells. 2000 Nov 15 1
25 10413457 Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest. 1999 Jul 13 1
26 10597242 Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest. 1999 Nov 11 1
27 9516963 Selective sensitization to DNA-damaging agents in a human rhabdomyosarcoma cell line with inducible wild-type p53 overexpression. 1998 Jan 1
28 9664139 Bcl-2 overexpression is associated with resistance to dexamethasone, but not melphalan, in multiple myeloma cells. 1998 Aug 1
29 9685342 Stabilization of p53 by adenovirus E1A occurs through its amino-terminal region by modification of the ubiquitin-proteasome pathway. 1998 Aug 7 2
30 9794234 Dexamethasone-mediated protection from drug cytotoxicity: association with p21WAF1/CIP1 protein accumulation? 1998 Sep 24 10
31 9058378 Repression of glucocorticoid receptor transactivation and DNA binding of a glucocorticoid response element within the serum/glucocorticoid-inducible protein kinase (sgk) gene promoter by the p53 tumor suppressor protein. 1997 Mar 3
32 9191791 Chemotherapy of human malignant glioma: prevention of efficacy by dexamethasone? 1997 Jun 1
33 8806692 p53-independent growth regulation of cervical cancer cells by the papillomavirus E6 oncogene. 1996 Sep 5 1
34 8931502 Cytologic changes in two cervical carcinoma cell lines after transfection of the wild-type p53 gene. 1996 Oct 3
35 8986612 Intranuclear redistribution of SV40T, p53, and PML in a conditionally SV40T-immortalized cell line. 1996 Dec 15 1
36 21541525 bcl-2 plays a major role in resistance to dexamethasone induced apoptosis in multiple myeloma cell lines. 1996 Aug 5
37 21544419 The role of p53, bcl-2 and bax network in dexamethasone induced apoptosis in multiple myeloma cell lines. 1996 Apr 8
38 7730147 Inhibition by differentiation-inducing agents of wild-type p53-dependent apoptosis in HL-60 cells. 1995 Feb 4
39 7936649 The carboxy-terminal serine 392 phosphorylation site of human p53 is not required for wild-type activities. 1994 Nov 1
40 8151752 Reversible repression of papillomavirus oncogene expression in cervical carcinoma cells: consequences for the phenotype and E6-p53 and E7-pRB interactions. 1994 May 1
41 8117626 Wild-type p53 tumor suppressor gene restores differentiation of human squamous carcinoma cells but not the response to transforming growth factor beta. 1993 Dec 3
42 1459195 Effects of exogenous wild-type p53 on a human lung carcinoma cell line with endogenous wild-type p53. 1992 Dec 3